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Nathan Goodyear

Boswellic acid exerts antitumor effects in co... [Carcinogenesis. 2012] - PubMed - NCBI - 0 views

www.ncbi.nlm.nih.gov/...22983985

Boswellia Frankincense cancer NF-kappaB 5-lipoxygenase

shared by Nathan Goodyear on 01 Dec 13 - No Cached
  • Nathan Goodyear on 01 Dec 13
     
    Boswellia, Frankincense, shown to have anti-tumor effects in colorectal cancer.  The effects were found against 5-lipoxygenase and NF-kappaB.  This article proposes that effects are through a modulation of specific microRNA pathways.
Nathan Goodyear

Pharmacological basis for the role of curcumin in chronic diseases: an age-old spice wi... - 0 views

www.cell.com/...S0165-6147(08)00252-6

inflammation curcumin NF-kappaB TNF-alpha IL-1 IL-6 disease

shared by Nathan Goodyear on 22 Mar 16 - No Cached
  • Nathan Goodyear on 22 Mar 16
     
    Just abstract available here.  Curcumin reduces NF-kappaB, Cox2 and 5 lipoxygenase and the cytokines TNF-alpha and IL-1 and IL-6.  This implicates curcumin as an adjuvant for all chronic diseases of aging that involve inflammation.
Nathan Goodyear

Testosterone suppresses phospholipase D, causing sex differences in leukotriene biosynt... - 0 views

www.fasebj.org/...3377.full

Testosterone monocytes CVD cardiovascular disease inflammation men male hormones hormone women female 5-lipoxygenase DHT

shared by Nathan Goodyear on 14 Aug 14 - No Cached
  • Nathan Goodyear on 14 Aug 14
     
    In this study, the benefits of Testosterone was found to reduce 5-LO activity.  This has implications in CVD in men.  No evidence was found for 5alpha-DHT.
Nathan Goodyear

Modulation of arachidonic acid metabolism by curcumin and related β-diketone ... - 0 views

carcin.oxfordjournals.org/...1671.long

curcumin tumeric inflammation

shared by Nathan Goodyear on 13 Sep 13 - No Cached
  • Nathan Goodyear on 13 Sep 13
     
    Full text of curmin's inhibition of COX and LOX.
Nathan Goodyear

ScienceDirect - Trends in Pharmacological Sciences : Pharmacological basis for the role... - 0 views

www.sciencedirect.com/science

curcumin disease inflammation anti-inflammatory

shared by Nathan Goodyear on 29 Mar 11 - No Cached
  • Extensive research within the past two decades has shown that curcumin mediates its anti-inflammatory effects through the downregulation of inflammatory transcription factors (such as nuclear factor κB), enzymes (such as cyclooxygenase 2 and 5 lipoxygenase) and cytokines (such as tumor necrosis factor, interleukin 1 and interleukin 6)
  • Nathan Goodyear on 29 Mar 11
     
    curcumin as anti-inflammatory in disease
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