review of the evidence for probiotics in acne.

low vitamin A and vitamin E correlate with acne.

low Zinc associated with worsening acne

Only abstract available here--high Estradiol:Testosterone, thus high aromatase activity, increased abdominal fat and reduced lean muscle mass.  The authors also reported an higher bone mineral density, but that pales in the comparison of the metabolic dysfunction of high fat and low muscle mass causes.

only abstract available, but low Testosterone and elevated hs-CRP are found to predict metabolic syndrome in men.

new study finds that bariatric surgery outperforms lifestyle interventions in improving glucose control in obese individuals.  On the surface this seems interesting, but the lifestyle interventions were based on the Diabetes Prevention program.  The diabetes prevention program doesn't do well in glucose control in any clients (see increasing diabetes rates), so it should be no surprise that bariatric surgery outperforms a program that doesn't work

What legacy do you leave your children?  Study finds that the "lard legacy" is one many leave their children.  Adults with high fatty acid profile, found in SAD, but this leaves alter gut microbiome in their children.

gut microbiome plays a role in metabolic syndrome, IR and it should come as no surprise--NAFLD

Gut effects on metabolism are widespread.

Intermittent fasting can be used as an adjunct for a healthy lifestyle transition in those with obesity, diabetes, and increased risk of CVD.

Intermittent fasting decreased biomarkers for aging, diabetes, CVD, and cancer.

Rat study finds intermittent fasting aids weight loss, improves insulin resistance, leptin signaling and blunts the effects of a high-fat (trans), high fructose, and high sugar diet.

new study finds Echinacea plus elderberry out performs Tamiflu in the treatment of early flu-like symptoms.  This study was fairly large for a head to head randomized study.  I love it when natural therapies out perform prescription meds.

Vitamin D plus calcium found to reduce inflammation and oxidative stress in women with PCOS.  CRP and MDA were decreased.  Notice dosing.

TSH positively associated with increase stroke in those adults less than 65.

Gut-brain connection via gut microbiome starts to move mainstream.

High dietary sugar intake alters gut bacteria (increased Clostridia sp. and decrease Bacteroidetes sp).  This resulted in decreased memory learning and memory in rat study.  

Acute inflammation is a response to an alteration induced by a pathogen or a physical or chemical insult, which functions to eliminate the source of the damage and restore homeostasis to the affected tissue. However, chronic inflammation triggers cellular events that can promote malignant transformation of cells and carcinogenesis. Several inflammatory mediators, such as TNF-α, IL-6, TGF-β, and IL-10, have been shown to participate in both the initiation and progression of cancer. In this review, we explore the role of these cytokines in important events of carcinogenesis, such as their capacity to generate reactive oxygen and nitrogen species, their potential mutagenic effect, and their involvement in mechanisms for epithelial mesenchymal transition, angiogenesis, and metastasis. Finally, we will provide an in-depth analysis of the participation of these cytokines in two types of cancer attributable to chronic inflammatory disease: colitis-associated colorectal cancer and cholangiocarcinoma.

Sex difference of gut flora has different metabolic effects from the same diet.  Could it all begin in the get?  Are gut flora sexist?  Of course not, but this study highlights the sex difference of the gut flora and the gender different effects.

autoimmune disease sexual preference appears to have Gut origins.