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Intermittent fasting can be used as an adjunct for a healthy lifestyle transition in those with obesity, diabetes, and increased risk of CVD.

Intermittent fasting decreased biomarkers for aging, diabetes, CVD, and cancer.

Intermittant fasting reduces inflammation, improved sugar control and reduces cardiovascular disease.

Rat study finds intermittent fasting aids weight loss, improves insulin resistance, leptin signaling and blunts the effects of a high-fat (trans), high fructose, and high sugar diet.

Dr. Seyfried provides a different perspective on cancer as a metabolic disease and not as a "genetic" disease as is the current dogma. Dr. Seyfried is well published on this topic and presents valid points to show that a ketogenic diet with intermittent fasting is anti-cancer.

Calorie restriction and protein restriction inhibit IGF-1, insulin, AkT, PI3K, and mTOR. In addition, those with protein intake >20%, compared to 10%, was associated with a 4 fold increase in cancer death risk and a 75% increase in overall mortality. Protein restriction inhibits tumor growth, associated with a 30-70% reduction in IGF-1, reduced the accumulation of oxidized proteins. The restriction of tryptophan alone reduced inflammation.