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Nathan Goodyear

Mitochondrial Dysfunction Is a Primary Event in Glutamate Neurotoxicity - 0 views

www.jneurosci.org/...6125.abstract

mitochondrial dysfunction

shared by Nathan Goodyear on 03 Mar 11 - No Cached
  • These results suggest that early mitochondrial damage plays a key role in induction of glutamate neurotoxicity.
  • Nathan Goodyear on 03 Mar 11
     
    mitochondrial dysfunction and neurotoxicity
Nathan Goodyear

Mitochondrial dysfunction in Parkinson's disease: ... [Parkinsons Dis. 2010] - PubMed r... - 0 views

www.ncbi.nlm.nih.gov/...21234411

mitochondrial dysfunction Parkinson's disease neurodegenerative

shared by Nathan Goodyear on 16 May 11 - No Cached
  • Nathan Goodyear on 16 May 11
     
    fantastic read on mitochondrial dysfunction and parkinson's disease
Nathan Goodyear

Chelation Therapy for Patients with Elevated Body Lead Burden and Progressive Renal Ins... - 0 views

www.annals.org/...7.short

lead burden toxicity chelation EDTA

shared by Nathan Goodyear on 05 Jul 11 - No Cached
  • helation therapy seems to slow the progression of renal insufficiency in patients with mildly elevated body lead burden.
  • implies that long-term exposure to low levels of environmental lead may be associated with impaired renal function in patients with chronic renal disease.
  • Nathan Goodyear on 05 Jul 11
     
    long-term lead exposure and body burden may be associated with renal dysfunction. Treatment of long-standing lead exposure with chelation benefits patients with renal dysfunction
Nathan Goodyear

Long-Term Glycemic Control Influences the Long-Lasting Effect of Hyperglycemia on Endot... - 0 views

jcem.endojournals.org/...2751.abstract

Vitamin C Diabetes endothelial dysfunction glycemic control

shared by Nathan Goodyear on 09 Jul 11 - No Cached
  • Combining insulin and vitamin C, however, normalized endothelial dysfunction and nitrotyrosine.
  • Nathan Goodyear on 09 Jul 11
     
    Vitamin C normalized vascular dysfunction found in Diabetes
Nathan Goodyear

Association of Pesticide Exposure with Neurologic Dysfunction and Disease - 0 views

www.ncbi.nlm.nih.gov/...PMC1247187

pesticide neurologic dysfunction organophospahtes organochlorides fungicides fumigants

shared by Nathan Goodyear on 01 Jul 11 - No Cached
  • Nathan Goodyear on 01 Jul 11
     
    pesticide exposure contributes to neurologic dysfunction
Nathan Goodyear

Cytokines in the Progression of Pancreatic β-Cell Dysfunction - 0 views

www.hindawi.com/...515136

inflammation cytokines inflammatory pancreas DM diabetes type II diabetes metabolic endotoxemia

shared by Nathan Goodyear on 15 Jan 13 - No Cached
  • Nathan Goodyear on 15 Jan 13
     
    inflammatory cytokines lead to progressive pancreatic Beta islet cells dysfunction and resultant diabetes.
Nathan Goodyear

Erectile dysfunction and coronary disease: Evaluating the link - 0 views

www.maturitas.org/...abstract

ED erectile dysfunction erectile dysfunction cardiovascular disease CVD heart disease

shared by Nathan Goodyear on 01 Jun 13 - No Cached
  • Nathan Goodyear on 01 Jun 13
     
    ED in men precedes cardiovascular disease by 3-5 years.
Nathan Goodyear

Androgens and sexual function: a placebo-controll... [Aging Male. 2009] - PubMed - NCBI - 0 views

www.ncbi.nlm.nih.gov/...19883295

aging male men DHEA ED low libido impotence sexual dysfunction

shared by Nathan Goodyear on 12 Jun 13 - No Cached
  • Nathan Goodyear on 12 Jun 13
     
    This study found no benefit from DHEA at 50 mg twice daily for those with androgen deficiency and sexual dysfunction.
Nathan Goodyear

Treatment of erectile dysfunction... [J Sex Marital Ther. 2003 May-Jun] - PubMed - NCBI - 0 views

www.ncbi.nlm.nih.gov/...12851125

erectile dysfunction ED erectile dysfunction l-Arginine Pycnogenol

shared by Nathan Goodyear on 30 Apr 13 - No Cached
  • Nathan Goodyear on 30 Apr 13
     
    l-Arginine with pycnogenol significantly improved ED over l-Arginine alone.
Nathan Goodyear

Relationship of visceral adipose tissue and glucose disposal is independent of sex in b... - 0 views

ajpendo.physiology.org/...E425.short

visceral fat adipose tissue adiposity IR insulin resistance glucose metabolic dysfunction

shared by Nathan Goodyear on 30 Mar 12 - No Cached
  • an inverse nonlinear relationship existed between glucose disposal and visceral fat
  • Nathan Goodyear on 30 Mar 12
     
    Increase in visceral fat reduces glucose "disposal".  Translated: as visceral adiposity increases, associated insulin resistance increases glucose levels and all associated metabolic dysfunction.
Nathan Goodyear

CONTRIBUTION OF A MITOCHONDRIAL PATHWAY TO EXCITOTOXIC NEURONAL NECROSIS - 0 views

www.ncbi.nlm.nih.gov/...PMC2713718

mitochondria dysfunction excitotoxicity disease disorders

shared by Nathan Goodyear on 14 Dec 11 - No Cached
  • Nathan Goodyear on 14 Dec 11
     
    mitochondria dysfunction contributes to excitotoxicity disorders.
Nathan Goodyear

Figure 1 : Adipocyte dysfunctions linking obesity to insulin resistance and t... - 0 views

www.nature.com/...nrm2391_F1.html

obesity insulin resistance diabetes adipose tissue inflammation TNF-alpha FFA

shared by Nathan Goodyear on 22 Dec 11 - No Cached
  • Nathan Goodyear on 22 Dec 11
     
    nice diagram of how adipocyte dysfunction leads to inflammation and insulin resistance, and increase FFA.
Nathan Goodyear

Physiologic progesterone reduces mitochondrial dysfunction and hippocampal cell loss af... - 0 views

www.sciencedirect.com/...S0014488605003493

progesterone bio-identical bioidentical hormone hormones TBI brain injury neurology mitochondria

shared by Nathan Goodyear on 29 Jan 12 - No Cached
  • Nathan Goodyear on 29 Jan 12
     
    Bioidentical progesterone shown to reduce post TBI mitochondrial dysfunction. This has significant implications on the ability of the damaged brain to heal and recover, thus limiting post-injury cognitive deficits.
Nathan Goodyear

Prevalence of Neuroendocrine Dysfunction in Patients Recovering from Traumatic Brain In... - 0 views

jcem.endojournals.org/...2752.full

TBI traumatic brain injury HGH pituitary cortisol thyroid hypothyroid hypothyroidism

shared by Nathan Goodyear on 03 Feb 12 - No Cached
  • Nathan Goodyear on 03 Feb 12
     
    TBI results in pituitary dysfunction.  The result in low cortisol, low thyroid, and low HGH.  Other hormones appeared to be unaffected
Nathan Goodyear

Acute Effects of Triiodothyronine (T3) Replacement Therapy in Patients with Chronic Hea... - 0 views

jcem.endojournals.org/...1351.short

T3 low cardiac dysfunction heart replacement

shared by Nathan Goodyear on 31 Jan 12 - No Cached
  • Nathan Goodyear on 31 Jan 12
     
    T3 replacement in people with low T3 and cardiac dysfunction found to improve cardiac performance.
Nathan Goodyear

NCJRS Abstract - National Criminal Justice Reference Service - 0 views

www.ncjrs.gov/...abstract.aspx

PTSD HPA dysfunction cortisol saliva salivary hormone hormones testing evaluation

shared by Nathan Goodyear on 03 Feb 12 - No Cached
  • Nathan Goodyear on 03 Feb 12
     
    PTSD is not just a short term issue.  The HPA dysfunction can persist long-term causing symptoms that extend far beyond the time of injury/healing.  What is interesting, is that the cortisol was evaluated with cortisol.  The new gold standard.
Nathan Goodyear

IOS Press - Journal Article - 0 views

iospress.metapress.com/...kj417684763h0523

Parkinson's disease mitochondrial dysfunction alpha-synuclein

shared by Nathan Goodyear on 18 Nov 11 - No Cached
  • Nathan Goodyear on 18 Nov 11
     
    study links mitochondrial dysfunction to Parkinson's disease. 
Nathan Goodyear

Insulin resistance and endothelial function are improved after folate and vitamin B12 t... - 0 views

eje-online.org/...483.full.pdf+html

metabolic syndrome vitamin B12 vitamins Folic acid IR insulin resistance endothelial dysfunction homocysteine

shared by Nathan Goodyear on 25 Jul 12 - No Cached
  • Nathan Goodyear on 25 Jul 12
     
    Vitamin B12 and Folic acid improves insulin resistance, endothelial dysfunction, and reduces homocysteine levels by 28% in those with metabolic syndrome.
Nathan Goodyear

Access : Impact of the association between elevated oestradiol and low testosterone lev... - 0 views

www.nature.com/...aja201320a.html

low T low Testosterone ED erectile dysfunction Estradiol male hormone hormones erectile dysfunction low testosterone

shared by Nathan Goodyear on 26 Aug 13 - No Cached
  • Nathan Goodyear on 26 Aug 13
     
    low T and elevated E2 result in ED in men.  The authors conclude that E2 provides an additive effect on that of low T.  Yet, they fail to realize the previous research that high aromatase activity (Testosterone to Estradiol production) causes the low T.
Nathan Goodyear

Low mercury concentrations cause oxidative stress and endothelial dysfunction in conduc... - 0 views

ajpheart.physiology.org/...H1033.long

Hg mercury hypertension NO ROS oxidative stress glutathione GHS cardiovascular disease heart

shared by Nathan Goodyear on 16 Sep 14 - No Cached
  • Nathan Goodyear on 16 Sep 14
     
    Hg induces vascular ROS through depletion of glutathione.  This study found that low dose, chronic Hg exposure induced ROS that resulted in vascular dysfunction i.e. hypertension.
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