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Nathan Goodyear

Levels of estradiol and testosterone are altered in Chinese men with sexual dysfunction... - 0 views

onlinelibrary.wiley.com/...abstract

male hormones' hormones estradiol Testosterone sexual dysfunction ED erectile dysfunction

shared by Nathan Goodyear on 12 Oct 16 - No Cached
  • Nathan Goodyear on 12 Oct 16
     
    Men with sexual dysfunction found to have higher E:T ratio and higher Estradiol overall.  This was a retrospective study.
Nathan Goodyear

Prevalence of Sexual Dysfunction among Postmenopausal Women with and without Metabolic ... - 0 views

onlinelibrary.wiley.com/...abstract

sexual dysfunction metabolic syndrome MetS

shared by Nathan Goodyear on 17 Feb 12 - No Cached
  • Nathan Goodyear on 17 Feb 12
     
    sexual dysfunction found more in women with metabolic syndrome versus healthy women.
Nathan Goodyear

The Association of Exercise with Both Erectile and Sexual Function in Black and White M... - 0 views

onlinelibrary.wiley.com/...abstract

exercise men ED erectile dysfunction

shared by Nathan Goodyear on 24 Mar 15 - No Cached
  • Nathan Goodyear on 24 Mar 15
     
    Highly active men report better sexual function/performance than less active men, though less active men were not found to have ED or sexual dysfunction.
Nathan Goodyear

Androgens and sexual function: a placebo-controll... [Aging Male. 2009] - PubMed - NCBI - 0 views

www.ncbi.nlm.nih.gov/...19883295

aging male men DHEA ED low libido impotence sexual dysfunction

shared by Nathan Goodyear on 12 Jun 13 - No Cached
  • Nathan Goodyear on 12 Jun 13
     
    This study found no benefit from DHEA at 50 mg twice daily for those with androgen deficiency and sexual dysfunction.
Nathan Goodyear

Testosterone Treatment and Sexual Function in Older Men with Low Testosterone Levels: T... - 0 views

press.endocrine.org/...jc.2016-1645

low T low Testosterone Testosterone male hormones libido ED estradiol hormones

shared by Nathan Goodyear on 13 Jul 16 - No Cached
  • Nathan Goodyear on 13 Jul 16
     
    new study finds that men >65 with low libido and Testosterone levels < 275 increase sexual function with Testosterone therapy.  Only libido was improved; no benefit to erectile function was noted--note that is likely due to depleted NO.  Given time that should improve with he increase in NO synthase and thus NO.  I have a fault with on elf the comments on this study: they point out that increased free Testosterone and estradiol levels were associated with improved sexual activity.  This lacks an understanding of the physiology.  In men with low T > 65, the majority are dealing with inflammation and excess weight; all of which increase aromatase activity and thus estradiol activity.  This does not indicate that an increase in estradiol activity is associated with improved libido in men.  How can elevated estrogen levels lead to low T and then increase levels are associated with improved libido?  This is merely a reflection of the body's dysfunctional physiology.  This observation of increased estradiol by no means shows cause and effect.  Scientists need to due a better job in vetting what they write!
Nathan Goodyear

Persistent sexual dysfunction after discontinuatio... [J Sex Med. 2008] - PubMed result - 0 views

www.ncbi.nlm.nih.gov/...18173768

sexual side effects SSRI anti-depressants

shared by Nathan Goodyear on 09 Dec 10 - No Cached
  • SSRIs can cause long-term effects on all aspects of the sexual response cycle that may persist after they are discontinued
  • Nathan Goodyear on 09 Dec 10
     
    Sexual side effects often persist long after SSRIs stopped
Nathan Goodyear

Testosterone Supplementation and Sexual Function: ... [J Sex Med. 2014] - PubMed - NCBI - 0 views

www.ncbi.nlm.nih.gov/...24697970

low T Testosterone male hypogonadism hormone hormones libido bias men

shared by Nathan Goodyear on 06 Apr 14 - No Cached
  • Nathan Goodyear on 06 Apr 14
     
    Meta-analysis finds bias in industry studies versus independent studies.  No surprise there.   Testosterone in this meta-analysis was found to aid sexual dysfunction in men with hypogonadism.
Nathan Goodyear

International Journal of Impotence Research - Obesity, low testosterone levels and erec... - 0 views

www.nature.com/...ijir200842a.html

low T low Testosterone men male hormone hormones ED erectile dysfunction Testosterone diabetes metabolic syndrome obesity

shared by Nathan Goodyear on 27 Jan 15 - No Cached
  • Studies have shown that ED may be an early biomarker of general endothelial dysfunction, atherosclerosis and CVD
  • testosterone treatment of hypogonadal young and older men improves sexual function, increases lean mass and decreases fat mass
  • In men with low serum testosterone (for example, &lt;8 or 230 nmol l−1) with obesity, metabolic syndrome and diabetes mellitus, treatment with testosterone is warranted
  • ...12 more annotations...
  • In obese middle-aged men, testosterone treatment reduced visceral adipocity, insulin resistance, serum cholesterol and glucose levels
  • testosterone replacement has a favorable impact on body mass, insulin secretion and sensitivity, lipid profile and blood pressure in hypogonadal men with the metabolic syndrome as well as type 2 diabetes mellitus
  • Testosterone significantly inhibits lipoprotein lipase activity, which reduces triglycerides uptake into adipocytes in the abdominal adipose tissue
  • testosterone treatment decreased endogenous inflammatory cytokines (tumor necrosis factor-α and IL-1β) and lipids (total cholesterol) and increased IL-10 in hypogonadal men
  • Testosterone treatment reduced leptin and adiponectin levels in hypogonadal type 2 diabetic men after 3 months of testosterone replacement
  • available data clearly show a relationship between obesity, low testosterone levels and ED
  • Obesity adversely affects endothelial function and lowers serum testosterone levels through the development of insulin resistance and metabolic syndrome
  • Metabolic disturbances as well as production of cytokines and adipokines by inflamed fat cells may be causal factors in the development of ED
  • The onset of ED and the associated risk of CVD may be delayed through lifestyle modifications that affect obesity, such as diet and exercise
  • Very low testosterone levels contribute to the development of ED in obesity, metabolic syndrome and type 2 diabetes mellitus
  • Obesity is associated with low total testosterone levels that can be explained at least partially by lower sex hormone-binding globulin (SHBG) in obese men
  • epidemiological studies have shown a negative correlation between BMI and total testosterone and to a lesser extent with free and bioavailable (biologically active) testosterone levels
  • Nathan Goodyear on 27 Jan 15
     
    Obesity is associated with low Testosterone and ED in men.
Nathan Goodyear

Chronic kidney disease and erectile dysfunction - 0 views

www.ncbi.nlm.nih.gov/...PMC4220354

ED erectile dysfunction Zinc Zn sexual dysfunction

shared by Nathan Goodyear on 09 Mar 17 - No Cached
hoangkimchi liked it
  • Nathan Goodyear on 09 Mar 17
     
    Zinc deficiency implicated in ED in men.  In addition, zinc supplementation improves ED in men.
Nathan Goodyear

Effect of antihypertensive treatment with valsartan or atenolol on sexual activity and ... - 0 views

www.ncbi.nlm.nih.gov/...12107602

beta blockers medications sexual dysfunction Testosterone men hormones low t low Testosterone

shared by Nathan Goodyear on 27 Sep 15 - No Cached
  • Nathan Goodyear on 27 Sep 15
     
    Beta blocker therapy resulted in decreased sexual activity and serum Testosterone levels compared to AARB therapy.
Nathan Goodyear

Effects of zinc supplementation on sexual behavior of male rats - 0 views

www.ncbi.nlm.nih.gov/...PMC2800928

zinc Zn Testosterone hormones male hormones libido sexual dysfunction prolactin

shared by Nathan Goodyear on 09 Mar 17 - No Cached
  • Nathan Goodyear on 09 Mar 17
     
    rat study finds that zinc supplementation increases Testosterone and prolactin levels, which increase sexual performance.
trungtamnamkhoa

Pharma Injectable Sust 250mg of the faculty Men's Health - 1 views

nhathuocnamkhoa.com/...pharma-sust-250mg

hormones hormone Testosterone Men health healthy men's PHARMA SUST

shared by trungtamnamkhoa on 25 Jun 19 - No Cached
  • trungtamnamkhoa on 25 Jun 19
     
    Pharma Sust 250mg injections treat hypogonadism disorders in men, after the illness, impotence due to lack of hormones, menstrual symptoms in men such as reducing sexual pleasure and physiological activities. Side effects: The drug can cause erectile dysfunction, signs of excessive sexual stimulation, reduced sperm count, decreased volume of ejaculation, water & salt retention. In pre-puberty boys: develop sex early, increase the frequency of erectile dysfunction, enlargement of the penis, and early growth of bone heads.
Nathan Goodyear

Mary Ann Liebert, Inc. - Journal of Women's Health - 20(4):559 - 0 views

www.liebertonline.com/...jwh.2009.1915

BHRT bioidentical hormones treatment therapy hormone sexual dysfunction libido conventional HRT

shared by Nathan Goodyear on 29 Nov 11 - No Cached
  • Nathan Goodyear on 29 Nov 11
     
    BHRT shown to be significantly better for sexual  symptoms than with conventional HRT.  78% vs 33%.
Nathan Goodyear

Metabolic effects of testosterone replacement therapy on hypogonadal men with type 2 di... - 0 views

www.ajandrology.com/article.asp

Testosterone therapy diabetes lipids glucose triglycerides men male hormone hormones

shared by Nathan Goodyear on 17 Jan 14 - No Cached
  • up to 40% of men with T2DM have testosterone deficiency
  • Among diabetic patients, a reduction in sex hormone binding globulin levels induced by insulin resistance leads to a further decline of testosterone levels
  • low bioavailable testosterone concentration was related to decreased lean body mass and muscle strength
  • ...13 more annotations...
  • Testosterone deficiency has a high prevalence in men with T2DM, and it is also associated with impaired insulin sensitivity, increased percentage body fat, central obesity, dyslipidemia, hypertension and cardiovascular diseases (CVD)
  • A meta-analysis of four randomized controlled trials (RCTs) showed that TRT seemed to improve glycemic control as well as fat mass in T2DM subjects with low testosterone levels and sexual dysfunction.
  • testosterone administration could increase muscle mass and strength
  • Insulin stimulates glucose uptake into muscle and adipose tissue via the Glut4 glucose transporter isoform. When insulin activates signaling via the insulin receptor, Glut4 interacts with insulin receptor substrate 1 to initialize intracellular signaling and facilitate glucose transportation into the cell
  • The benefits of TRT on glucose metabolism can mainly be explained by its influence on the insulin signaling pathway
  • Insulin resistance as assessed by, which is calculated from the equation (If*Gf/22.5, where If is fasting insulin and Gf is fasting glucose), was definitely improved by TRT after testosterone administration in three studies
  • Testosterone was observed to elevate the expression levels and stimulate translocation of Glut4 in cultured skeletal muscle cells and to upregulate Glut4 by activating insulin receptor signaling pathways in neonatal rats
  • These effects were inhibited by a dihydrotestosterone (DHT) blocker, indicating that glucose uptake may correlate with conversion of testosterone to DHT and activation of the androgen receptor.
  • TRT reduced triglyceride levels
  • TRT has been reported to have a positive effect in the decrease of total and LDL cholesterol levels and triglycerides in hypogonadal men
  • a recent meta-analysis showed that statins could significantly lower testosterone concentrations.
  • Epidemiological studies have found a negative relationship between testosterone levels and typical cardiovascular risk markers, such as body mass index, waist circumference, visceral adiposity and carotid intima-media thickness.
  • Testosterone treatment was shown to raise hemoglobin, hematocrit and thromboxane, all of which might give rise to CVD
  • Nathan Goodyear on 17 Jan 14
     
    Low Testosterone is a very significant problem in men with type II Diabetes.  Estimated to reach 40%, likely much higher.  They based these estimates only on T levels and sexual symptoms. Testosterone improves glycemic control primarily through Increased transcription and transloction of GLUT4 insulin receptors to the cell surface.  Inflammation reduction is also a mechanism.  Testosteorne lowers Triglycerides in the traditional lipid profile.  Studies are mixed on the other aspects of  lipids.  
Nathan Goodyear

The Prevalence of Hypoactive Sexual Desire Disorder in Surgically Menopausal Women: An ... - 0 views

onlinelibrary.wiley.com/...abstract

low libido sexual dysfunction hormones

shared by Nathan Goodyear on 11 Jan 11 - No Cached
  • Nathan Goodyear on 11 Jan 11
     
    Low Hormones, post-ovary removal, linked to low libido
Nathan Goodyear

Is erectile dysfunction a low-grade systemic inflammatory condition? - 0 views

eurheartj.oxfordjournals.org/...642.full

inflammation erectile dysfunction ED men sexual

shared by Nathan Goodyear on 02 Sep 13 - No Cached
  • Nathan Goodyear on 02 Sep 13
     
    ED is the result of low-grade, chronic inflammation.
Nathan Goodyear

Hormonal Modulation in Aging Patients with Erectile Dysfunction and Metabolic Syndrome - 0 views

www.ncbi.nlm.nih.gov/...PMC3888699

low T Testosterone hypogonadism MetS metabolic syndrome men male hormone hormones

shared by Nathan Goodyear on 05 Feb 14 - No Cached
  • Hypogonadism and MetS are strongly associated [12, 13, 16], having even been demonstrated that with the increasing number of MetS parameters there is a proportional raise in the incidence of hypogonadism
  • increasing number of MetS components is inversely associated with T levels
  • the presence of MetS did not prove to be a significant determinant of hypogonadism, as it did not lead to a decline in T levels, in MetS patients with already established hypogonadism, the increasing number of MetS features was associated with further decline in T
  • ...15 more annotations...
  • In the setting of MetS, hypertriglyceridemia and increased WC have been reported as the most important determinants of hypogonadism
  • recent literature consistently associates obesity not only with higher risk of hypogonadism [4, 6, 27] but also with lower T levels
  • Visceral adiposity has been particularly related with reduction of T and SHBG levels (independent of other metabolic disorders)
  • WC was one of the MetS parameters with the greatest influence in T levels decrease, presenting itself as a strong risk factor for hypogonadism development
  • MetS-related T decline was not accompanied by an increase in pituitary LH levels, suggesting impairment in gonadotropin secretion
  • The molecules behind this smoothing compensatory effect of GnRH/LH are still unknown, but estrogens and insulin, as well as leptin, TNF-α, and other adipokines, were proposed candidates
  • fat stores undertake an increase aromatization of androgens, therefore raising estrogen levels [9, 15], which in turn decrease LH secretion
  • our data contradicts the concept that estradiol exerts a negative feedback on hypothalamic GnRH secretion
  • taking into account that high estradiol levels have already been described as the only abnormality in a subset of patients with ED, the hypothesis that the later might not only be caused by androgen deficiency is becoming increasingly evident
  • it has been reported that the chronic exposure to phosphodiesterase type 5 inhibitors (PDE5i), widely used for the treatment of ED, may influence serum estradiol levels
  • thyroid disorders (specially hyperthyroidism) have been related to ED and hypogonadism, and so must be considered in a sexual-dysfunction setting
  • It is clear from the current literature that collecting a more thorough hormonal panel might be a wise approach to further uncover hormonal relations
    • Nathan Goodyear
      Nathan Goodyear on 05 Feb 14
       
      outstanding point.  This hits to the point that Low T is the effect not the cause.
  • We concluded that in ED patients with hypogonadism and MetS, the attenuated response of HPG axis (normal or low LH levels) might not always be due to an underlying adiposity-dependent estrogen-raising effect.
  • our findings indicate that ED, aging, and estradiol might have a stronger connection than what is currently described in the literature.
  • this study underlines the importance of the collection of a full hormonal panel in ED men
  • Nathan Goodyear on 05 Feb 14
     
    low T strongly associated with metabolic syndrome in men.
Rachna Clinic

Why Are You Searching Repudiated Sexual Ayurvedic Medico in Delhi? - 0 views

rachanaclinic.blogspot.in

sexual dysfunction erectile disorder sex problems

shared by Rachna Clinic on 30 Jul 13 - No Cached
  • Rachna Clinic on 30 Jul 13
     
    Sex is one of the most significant and pleasurable activities for men and women. Persons don't have sex only to conceive offspring. Why persons extend to have sex after having children? I have renowned numerous persons who relish sex even after the age of seventies so sex has no expiry time.
Nathan Goodyear

Low Testosterone Associated With Obesity and the Metabolic Syndrome Contributes to Sexu... - 0 views

care.diabetesjournals.org/...1669.full

low testosterone obesity metabolic syndrome cardiovascular disease diabetes CVD men male hormone hormones

shared by Nathan Goodyear on 28 Aug 13 - No Cached
  • Nathan Goodyear on 28 Aug 13
     
    Low T associated with metabolic syndrome, CVD, type 2 Diabetes in men.
Nathan Goodyear

Association Between Viral Hepatitis and Erectile Dysfunction: A Population-Based Case-C... - 0 views

onlinelibrary.wiley.com/...4B3F25DEF6C04C3FE9AA4A6.f03t02

low T low Testosterone Testosterone men male hormone hormones ED libido hepatitis Hepatitis C

shared by Nathan Goodyear on 22 Apr 15 - No Cached
  • Nathan Goodyear on 22 Apr 15
     
    Low Testosterone, low libido, and ED associated with prior hepatitis B and hepatitis C.  
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