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Nathan Goodyear

Dietary glycemic index, glycemic load, and the risk of breast cancer in an Italian pros... - 0 views

ajcn.nutrition.org/...1160.full

nutrition diet glycemic index glycemic load cancer breast cancer carbohydrates sugar menopause women premenopause

shared by Nathan Goodyear on 09 Dec 14 - No Cached
  • GI is a measure of carbohydrate quality in relation to glucose availability and is independent of quantity, whereas GL is a measure of the total glycemic effect and hence is anindicator of the insulin demand of the diet. High-glycemic diets are in fact generally associated with greater insulin secretion
  • the consumption of large quantities of high-GI foods rather than the consumption of high quantities of carbohydrates is linked to the development of breast cancer.
  • Nathan Goodyear on 09 Dec 14
     
    High glycemic load and glycemic index associated with increased breast cancer risk in premenopausal women.
Nathan Goodyear

Influence of high-carbohydrate mixed meals with different glycemic indexes on substrate... - 0 views

www.ajcn.org/...354.abstract

obesity overweight weight-loss low-glycemic exercise adipose fat

shared by Nathan Goodyear on 20 Dec 11 - No Cached
  • Nathan Goodyear on 20 Dec 11
     
    low-glycemic index diet aids in mobilization of adipose tissue in exercise.  In this study, exercise after a low-glycemic meal resulted in a greater mobilization of adipose tissue for energy production than a high glycemic meal.  This will help  in weight loss
Nathan Goodyear

Dietary glycemic index, glycemic load, and cancer risk: results from the EPIC-Italy stu... - 0 views

www.nature.com/...s41598-017-09498-2

glucose glycemic index glycemic load cancer diabetes

shared by Nathan Goodyear on 20 Sep 17 - No Cached
  • Nathan Goodyear on 20 Sep 17
     
    High glycemic index diet was found to be associated with increased risk of colon and bladder cancer where as a high glycemic load was associated with increased risk of colon cancer and other diabetes-related cancers.
Nathan Goodyear

International Tables of Glycemic Index and Glycemic Load Values: 2008 - 1 views

www.ncbi.nlm.nih.gov/...PMC2584181

glycemic index load

shared by Nathan Goodyear on 16 Aug 13 - No Cached
  • Nathan Goodyear on 16 Aug 13
     
    Great article from 2008 that discusses glycemic index and glycemic load.  What is great about this article is the supplementary appendix listing the above for > 1000 items.
Nathan Goodyear

http://annonc.oxfordjournals.org/content/12/11/1533.full.pdf#page=1&view=FitH - 0 views

annonc.oxfordjournals.org/...1533.full.pdf

cancer carbohydrates insulin breast cancer diet nutrition glycemic index glycemic load IGF-1 SHBG

shared by Nathan Goodyear on 09 Dec 14 - No Cached
  • Nathan Goodyear on 09 Dec 14
     
    Study finds link between higher glycemic index and glycemic load with increased breast cancer risk.   The proposed mechanisms are: hyperinsulinemia and its affinity for IGF-1 receptor resulting in a + growth signal.  Increased IGF-1 via the same mechanism. Insulin and IGF-1 have negative regulation effects on SHBG. This all makes sense as insulin receptors are highly expressed on cancer cells.
Nathan Goodyear

A low-glycemic-load diet improves symptoms in acne vulgaris patients: a randomized cont... - 0 views

www.ajcn.org/...107.full

low glycemic diet acne insulin

shared by Nathan Goodyear on 31 May 11 - No Cached
  • The improvement in acne and insulin sensitivity after a low-glycemic-load diet suggests that nutrition-related lifestyle factors may play a role in the pathogenesis of acne
  • Nathan Goodyear on 31 May 11
     
    low-glycemic diet improves acne
Nathan Goodyear

Effect of a low glycemic index compared with a conventional healthy diet on polycystic ... - 0 views

www.ajcn.org/...83.short

PCO PCOS polycystic ovaries ovarian syndrome low GI glycemic low-glycemic diet

shared by Nathan Goodyear on 10 Sep 11 - No Cached
  • Nathan Goodyear on 10 Sep 11
     
    low glycemic diet for ladies with polycystic ovaries
Nathan Goodyear

The effect of a low-carbohydrate, ketogenic diet versus a low-glycemic index diet on gl... - 0 views

www.ncbi.nlm.nih.gov/...PMC2633336

ketogenic diet ketogenic nutrition diabetes lifestyle diet glycemic index

shared by Nathan Goodyear on 26 Feb 16 - No Cached
  • Nathan Goodyear on 26 Feb 16
     
    low carb ketogenic diet outperforms low glycemic index in diabetes.
Nathan Goodyear

Dietary glycemic load and atherothrombo... [Curr Atheroscler Rep. 2002] - PubMed - NCBI - 0 views

www.ncbi.nlm.nih.gov/...12361493

glycemic load

shared by Nathan Goodyear on 16 Aug 13 - No Cached
  • Nathan Goodyear on 16 Aug 13
     
    glycemic load
Nathan Goodyear

A low-glycemic index diet combined with exerc... [Am J Clin Nutr. 2010] - PubMed - NCBI - 0 views

www.ncbi.nlm.nih.gov/...20980494

low-glycemic diet insulin resistance

shared by Nathan Goodyear on 06 Sep 11 - No Cached
  • Nathan Goodyear on 06 Sep 11
     
    low glycemic index diet improves insulin and glucose control in pre-diabetics
Nathan Goodyear

Effect of Testosterone Treatment on Glucose Metabolism in Men With Type 2 Diabetes: A R... - 0 views

care.diabetesjournals.org/...2098.abstract

Testosterone treatment low subcutaneous fat visceral fat T glucose insulin resistance metabolism obesity diabetes men male hormone hormones

shared by Nathan Goodyear on 29 Jul 14 - No Cached
  • Nathan Goodyear on 29 Jul 14
     
    Only the abstract available in this publication.  Good study design.  No improvement in insulin resistance, glycemic control or visceral adiposity in obese men with type II diabetes.  The levels of inclusion were TT < 346, which would not meet the criteria put forth by other studies.  This study appeared to look at border line "low T" men with obesity and type II diabetes and found no direct glycemic control improvement.  An increase in lean muscle mass and decrease in subcutaneous fat was found.
Nathan Goodyear

Dietary glycemic index and glycemic load and breast cancer risk in the European Prospec... - 0 views

www.ajcn.org/...ajcn.111.026724.abstract

dietary glycemic index nutrition breast cancer breast cancer women postmenopausal carbohydrates high ER PR

shared by Nathan Goodyear on 11 Jul 12 - No Cached
  • Nathan Goodyear on 11 Jul 12
     
    high carbohydrate intake associated with increased risk of ER/PR negative breast cancer in Postmenopausal women.
Nathan Goodyear

Zinc and diabetes--clinical links and molecul... [J Nutr Biochem. 2009] - PubMed - NCBI - 0 views

www.ncbi.nlm.nih.gov/...19442898

Zinc Zn diabetes DM glucose

shared by Nathan Goodyear on 31 Aug 12 - No Cached
  • Zinc supplementation of animals and humans has been shown to ameliorate glycemic control in type 1 and 2 diabetes, the two major forms of diabetes mellitus, but the underlying molecular mechanisms have only slowly been elucidated. Zinc seems to exert insulin-like effects by supporting the signal transduction of insulin and by reducing the production of cytokines, which lead to beta-cell death during the inflammatory process in the pancreas in the course of the disease
  • Nathan Goodyear on 31 Aug 12
     
    Zn show to help in glycemic control in both type I and II diabetics.  It appears to do this through inflammation reduction and thus improved insulin/Receptor signal transduction.   Also of note, antibodies against Zn transporter have been found in type I DM.
Nathan Goodyear

Metabolic effects of testosterone replacement therapy on hypogonadal men with type 2 di... - 0 views

www.ajandrology.com/article.asp

Testosterone therapy diabetes lipids glucose triglycerides men male hormone hormones

shared by Nathan Goodyear on 17 Jan 14 - No Cached
  • up to 40% of men with T2DM have testosterone deficiency
  • Among diabetic patients, a reduction in sex hormone binding globulin levels induced by insulin resistance leads to a further decline of testosterone levels
  • low bioavailable testosterone concentration was related to decreased lean body mass and muscle strength
  • ...13 more annotations...
  • Testosterone deficiency has a high prevalence in men with T2DM, and it is also associated with impaired insulin sensitivity, increased percentage body fat, central obesity, dyslipidemia, hypertension and cardiovascular diseases (CVD)
  • A meta-analysis of four randomized controlled trials (RCTs) showed that TRT seemed to improve glycemic control as well as fat mass in T2DM subjects with low testosterone levels and sexual dysfunction.
  • testosterone administration could increase muscle mass and strength
  • Insulin stimulates glucose uptake into muscle and adipose tissue via the Glut4 glucose transporter isoform. When insulin activates signaling via the insulin receptor, Glut4 interacts with insulin receptor substrate 1 to initialize intracellular signaling and facilitate glucose transportation into the cell
  • The benefits of TRT on glucose metabolism can mainly be explained by its influence on the insulin signaling pathway
  • Insulin resistance as assessed by, which is calculated from the equation (If*Gf/22.5, where If is fasting insulin and Gf is fasting glucose), was definitely improved by TRT after testosterone administration in three studies
  • Testosterone was observed to elevate the expression levels and stimulate translocation of Glut4 in cultured skeletal muscle cells and to upregulate Glut4 by activating insulin receptor signaling pathways in neonatal rats
  • These effects were inhibited by a dihydrotestosterone (DHT) blocker, indicating that glucose uptake may correlate with conversion of testosterone to DHT and activation of the androgen receptor.
  • TRT reduced triglyceride levels
  • TRT has been reported to have a positive effect in the decrease of total and LDL cholesterol levels and triglycerides in hypogonadal men
  • a recent meta-analysis showed that statins could significantly lower testosterone concentrations.
  • Epidemiological studies have found a negative relationship between testosterone levels and typical cardiovascular risk markers, such as body mass index, waist circumference, visceral adiposity and carotid intima-media thickness.
  • Testosterone treatment was shown to raise hemoglobin, hematocrit and thromboxane, all of which might give rise to CVD
  • Nathan Goodyear on 17 Jan 14
     
    Low Testosterone is a very significant problem in men with type II Diabetes.  Estimated to reach 40%, likely much higher.  They based these estimates only on T levels and sexual symptoms. Testosterone improves glycemic control primarily through Increased transcription and transloction of GLUT4 insulin receptors to the cell surface.  Inflammation reduction is also a mechanism.  Testosteorne lowers Triglycerides in the traditional lipid profile.  Studies are mixed on the other aspects of  lipids.  
Nathan Goodyear

Effects of Weight Loss and Long-Term Weight Maintenance With Diets Varying in Protein a... - 0 views

circ.ahajournals.org/...2829.long

inflammation high protein diet obesity insulin resistance

shared by Nathan Goodyear on 21 Oct 13 - No Cached
  • Nathan Goodyear on 21 Oct 13
     
    High protein and high glycemic index intake are both associated with low grade inflammation.  An associated increase in cardiovascular risk was additionally found.
Nathan Goodyear

Dietary treatment of the metabolic syndrome--the o... [Br J Nutr. 2000] - PubMed - NCBI - 0 views

www.ncbi.nlm.nih.gov/...10889805

low glycemic index diet GI metabolic syndrome

shared by Nathan Goodyear on 13 Sep 11 - No Cached
  • Nathan Goodyear on 13 Sep 11
     
    low glycemic index diet is treatment of choice for metabolic syndrome
Nathan Goodyear

Resistance Training for Glycemic Control, Muscular Strength, and Lean Body Mass in Old ... - 0 views

www.ncbi.nlm.nih.gov/...28382531

diabetes sarcopenia sarcopenic obesity muscle weight lifting resistance training

shared by Nathan Goodyear on 17 Apr 17 - No Cached
  • Nathan Goodyear on 17 Apr 17
     
    8 weeks of resistance training in patients with sarcopenia and diabetes found to improve glycemic control
Nathan Goodyear

Treatment of Diabetes and Diabetic Complicati... [J Child Neurol. 2013] - PubMed - NCBI - 0 views

www.ncbi.nlm.nih.gov/...23680948

diabetes ketogenic diet ketogenic diet nutrition

shared by Nathan Goodyear on 03 Jul 13 - No Cached
  • Nathan Goodyear on 03 Jul 13
     
    Only the abstract, but for Diabetics, a ketogenic diet needs to include high fat and low protein.  Especially the elimination of animal protein.  A transition to a high protein diet will reduce ketosis.  The switch to ketosis from glucose will be what improves glycemic control.  The primary increase in most ketogenic or "low carb" diets today is an increase in protein.
Nathan Goodyear

Ketone supplementation decreases tumor cell viability and prolongs survival of mice wit... - 0 views

onlinelibrary.wiley.com/...full

cancer ketogenic ketogenic diet ketones

shared by Nathan Goodyear on 16 Nov 16 - No Cached
  • Nathan Goodyear on 16 Nov 16
     
    animal study finds that high glycemic diets increase risk of cancer, hyperglycemia = poor prognosis in those diagnosed with cancer, blood glucose levels correlated to tumor growth, ketogenc diet lowers glucose, insulin, IGF=1, and ketones directly inhibit tumor growth!!  So what is the cancer community waiting for?
Nathan Goodyear

Increased muscular dehydroepiandrosterone levels are associated with improved hyperglyc... - 0 views

ajpendo.physiology.org/...E274.abstract

exercise DHEA glucose DHT GLUT4 dihydrotestosterone

shared by Nathan Goodyear on 17 Mar 12 - No Cached
  • Nathan Goodyear on 17 Mar 12
     
    Exercise, DHEA, and DHT increased GLUT4 uptake of glucose, increasing glycemic control.
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