Indole-3-carbinol disrupts estrogen rece... [Mol Cell Endocrinol. 2012] - PubMed - NCBI - 0 views
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Nathan Goodyear on 18 Mar 13Indole-3-carbinol degrades ER alpha expression on breast cancer cells lines and down regulates ER alpha expression. Not only does I3C degrade ER alpha expression it inhibits its expression as well. Additionally, I3C interferes with signaling associated with ER alpha through IGF-1.