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Matti Narkia

NephroPal: Omega 3 Fatty Acid and Adiponectin Levels - 0 views

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    "Friday, December 18, 2009
    Omega 3 Fatty Acid and Adiponectin Levels
    Today my wife was watching the Oprah show. A commercial came on and I looked up. It was a Christmas special on liposuction in the local area. Considering that the fat tissue (adipose tissue) is now viewed as an endocrine organ and not just a collection of fat cells, I have always thought that sucking out the fat cells maybe a bad idea. Yet, I have never seen proof of this. But, the science of the adipose tissue as an endocrine organ is relatively new. It seems that in the medical literature adiponectin is receiving the most attention from all of the other adipose hormones - or also referred to as adipokines. This is for good reason. As stated before, adiponectin has the following effects:


    * reduces liver glucose production

    * increases glucose uptake in the muscles and adipose tissues

    * causes oxidation of fats which leads to less lipid production

    * has anti-inflammatory properties

    * protects the heart against ischemia and reduces myocardial infarct size

    * acts as an anti-clotting factor

    * increases nitric oxide production in the vasculature leading to a greater dilation of the vessels"
Matti Narkia

Whole Health Source: Omega-3 Eggs - 0 views

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    "Not everyone has access to pastured eggs. "Omega-3 eggs" come from hens fed an omega-3 enriched diet*. Not only do they have a much higher omega-3 content than conventional eggs, they also contain less AA. One study found that omega-3 eggs contain 39% less AA than conventional and organic eggs. Omega-3 eggs were also rich in short- and long-chain omega-3 fats. Omega-3 eggs are certainly not nutritionally equivalent to pastured eggs, but they're a step in the right direction. "
Matti Narkia

Omega 3 fatty acids and the brain: review of studies in depression (full text PDF) - 0 views

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    Omega 3 fatty acids and the brain: review of studies in depression.
    Sinclair AJ, Begg D, Mathai M, Weisinger RS.
    Asia Pac J Clin Nutr. 2007;16 Suppl 1:391-7. Review.
    PMID: 17392137

    This paper discusses the clinical studies conducted in the area of depression and omega 3 PUFA and the possible mechanisms of action of these PUFA. It is clear from the literature that DHA is involved in a variety of processes in neural cells and that its role is far more complex than simply influencing cell membrane properties.
Matti Narkia

High {omega}-6 and Low {omega}-3 Fatty Acids are Associated With Depressive Symptoms an... - 0 views

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    High omega-6 and low omega-3 fatty acids are associated with depressive symptoms and neuroticism.
    Conklin SM, Manuck SB, Yao JK, Flory JD, Hibbeln JR, Muldoon MF.
    Psychosom Med. 2007 Dec;69(9):932-4. Epub 2007 Nov 8.PMID: 17991818

    CONCLUSIONS: In conjunction with other reports, these findings suggest that the omega-3 and omega-6 fatty acids are related to negative affect at both the symptom and trait levels.
Matti Narkia

15-epi-lipoxin A4-mediated induction of nitric oxide explains how aspirin inhibits acut... - 0 views

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    15-epi-lipoxin A4-mediated induction of nitric oxide explains how aspirin inhibits acute inflammation.
    Paul-Clark MJ, Van Cao T, Moradi-Bidhendi N, Cooper D, Gilroy DW.
    J Exp Med. 2004 Jul 5;200(1):69-78.
    PMID: 15238606
Matti Narkia

Differential killing of human carcinoma cells supplemented with n-3 and n-6 polyunsatur... - 0 views

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    Differential killing of human carcinoma cells supplemented with n-3 and n-6 polyunsaturated fatty acids.
    Bégin ME, Ells G, Das UN, Horrobin DF.
    J Natl Cancer Inst. 1986 Nov;77(5):1053-62.
    PMID: 3464797
Matti Narkia

Dietary supplementation with eicosapentaenoic acid, but not with other long-chain n-3 o... - 0 views

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    Dietary supplementation with eicosapentaenoic acid, but not with other long-chain n-3 or n-6 polyunsaturated fatty acids, decreases natural killer cell activity in healthy subjects aged >55 y.
    Thies F, Nebe-von-Caron G, Powell JR, Yaqoob P, Newsholme EA, Calder PC.
    Am J Clin Nutr. 2001 Mar;73(3):539-48.
    PMID: 11237929
Matti Narkia

A lipidomic analysis of nonalcoholic fatty liver disease. - Hepatology. 2007 Oct - Wil... - 0 views

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    A lipidomic analysis of nonalcoholic fatty liver disease.
    Puri P, Baillie RA, Wiest MM, Mirshahi F, Choudhury J, Cheung O, Sargeant C, Contos MJ, Sanyal AJ.
    Hepatology. 2007 Oct;46(4):1081-90.
    PMID: 17654743
    DOI: 10.1002/hep.21763
Matti Narkia

Eating Your Way to Prostate Cancer - Life Extension - 0 views

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    A plethora of research documents the role of chronic inflammatory mediators such as 5-lipooxygenase (5-LOX) and tumor necrosis factor-alpha (TNF-α) in the manifestation and progression of prostate and other cancers.7-19,30,31,33,49,52-54,87,88

    The typical American diet is high in omega-6 fatty acids, saturated fats, and arachidonic acid. Over-consumption of these foods, and under-consumption of omega-3 fatty acids, contribute significantly to systemic chronic inflammatory states.

    Boswellia extracts have been thoroughly studied as natural remedies for inflammatory disorders. A patented extract from boswellia called 5-LOXIN® has potent ability to inhibit the enzyme 5-LOX, preventing the formation of protein-degrading enzymes, and protecting against inflammation-induced events that can promote tumor angiogenesis.
Matti Narkia

Docosahexaenoic acid-enriched egg consumption induces accretion of arachidonic acid in ... - 0 views

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    Docosahexaenoic acid-enriched egg consumption induces accretion of arachidonic acid in erythrocytes of elderly patients.
    Payet M, Esmail MH, Polichetti E, Le Brun G, Adjemout L, Donnarel G, Portugal H, Pieroni G.
    Br J Nutr. 2004 May;91(5):789-96.
    PMID: 15137931
    doi:10.1079/BJN20041106
Matti Narkia

Targeting lipoxygenases with care. - ScienceDirect - Chemistry & Biology 2006 Nov - 0 views

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    Targeting lipoxygenases with care.
    de Souza PM, Newson J, Gilroy DW.
    Chem Biol. 2006 Nov;13(11):1121-2.
    PMID: 17113992
    doi:10.1016/j.chembiol.2006.11.002  
Matti Narkia

Eicosapentaenoic acid perturbs signalling via the NFkappaB transcriptional pathway in p... - 0 views

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    Eicosapentaenoic acid perturbs signalling via the NFkappaB transcriptional pathway in pancreatic tumour cells.
    Ross JA, Maingay JP, Fearon KC, Sangster K, Powell JJ.
    Int J Oncol. 2003 Dec;23(6):1733-8.
    PMID: 14612948
Matti Narkia

Why fish oils may not always be adequate treatments for depression or other inflammator... - 0 views

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    Why fish oils may not always be adequate treatments for depression or other inflammatory illnesses: docosahexaenoic acid, an omega-3 polyunsaturated fatty acid, induces a Th-1-like immune response.
    Maes M, Mihaylova I, Kubera M, Bosmans E.
    Neuro Endocrinol Lett. 2007 Dec;28(6):875-80.
    PMID: 18063921
Matti Narkia

Modulation of inflammation in brain: a matter of fat. - J Neurochem. 2007 May - 0 views

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    Modulation of inflammation in brain: a matter of fat.
    Farooqui AA, Horrocks LA, Farooqui T.
    J Neurochem. 2007 May;101(3):577-99. Epub 2007 Jan 25. Review.
    PMID: 17257165
    DOI: 10.1111/j.1471-4159.2006.04371.x
Matti Narkia

Immunomodulation by omega-3 fatty acids - Prostaglandins Leukot Essent Fatty Acids. 200... - 0 views

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    Immunomodulation by omega-3 fatty acids.
    Calder PC.
    Prostaglandins Leukot Essent Fatty Acids. 2007 Nov-Dec;77(5-6):327-35. Epub 2007 Nov 26. Review.
    PMID: 18032006
    doi:10.1016/j.plefa.2007.10.015
Matti Narkia

Resolving inflammation: dual anti-inflammatory and pro-resolution lipid mediators : Abs... - 0 views

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    Resolving inflammation: dual anti-inflammatory and pro-resolution lipid mediators.
    Serhan CN, Chiang N, Van Dyke TE.
    Nat Rev Immunol. 2008 May;8(5):349-61. Review.
    PMID: 18437155
    doi:10.1038/nri2294
Matti Narkia

The relationship between the fatty acid composition of immune cells and their function ... - 0 views

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    The relationship between the fatty acid composition of immune cells and their function.
    Calder PC.
    Prostaglandins Leukot Essent Fatty Acids. 2008 Sep-Nov;79(3-5):101-8. Epub 2008 Oct 23. Review.
    PMID: 18951005
    doi:10.1016/j.plefa.2008.09.016
Matti Narkia

Novel omega -- 3-derived local mediators in anti-inflammation and resolution. - Science... - 0 views

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    Novel omega -- 3-derived local mediators in anti-inflammation and resolution.
    Serhan CN.
    Pharmacol Ther. 2005 Jan;105(1):7-21. Review.
    PMID: 15626453
    doi:10.1016/j.pharmthera.2004.09.002
Matti Narkia

Docosahexaenoic acid suppresses arachidonic acid-induced proliferation of LS-174T human... - 0 views

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    Docosahexaenoic acid suppresses arachidonic acid-induced proliferation of LS-174T human colon carcinoma cells.
    Habbel P, Weylandt KH, Lichopoj K, Nowak J, Purschke M, Wang JD, He CW, Baumgart DC, Kang JX.
    World J Gastroenterol. 2009 Mar 7;15(9):1079-84.
    PMID: 19266600
    doi: 10.3748/wjg.15.1079.
Matti Narkia

Phospholipase A(2) activation as a therapeutic approach for cognitive enhancement in ea... - 0 views

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    Phospholipase A(2) activation as a therapeutic approach for cognitive enhancement in early-stage Alzheimer disease.
    Schaeffer EL, Forlenza OV, Gattaz WF.
    Psychopharmacology (Berl). 2009 Jan;202(1-3):37-51. Epub 2008 Oct 14.
    PMID: 18853146
    DOI: 10.1007/s00213-008-1351-0
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