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Matti Narkia

MedWire News - Lipidology - High serum selenium associated with elevated LDL and total ... - 3 views

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    "High serum selenium associated with elevated LDL and total cholesterol
    By Helen Albert
    21 January 2010
    Atherosclerosis 2009; Advance online publication

    MedWire News: High levels of serum selenium are associated with elevated total and low-density lipoprotein (LDL) cholesterol, report US researchers.

    The results add weight to those of a previous UK study, reported by MedWire News, that reported an association between high plasma selenium and an adverse lipid profile.

    Eliseo Guallar (Johns Hopkins University Bloomberg School of Public Health, Baltimore, Maryland) and colleagues carried out a cross-sectional analysis of 1159 individuals aged 56.8 years on average who participated in the National Health and Nutrition Examination Survey (NHANES) 2003-2004."
Matti Narkia

Serum Long-Chain n-3 Polyunsaturated Fatty Acids and Risk of Hospital Diagnosis of Atri... - 0 views

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    Serum Long-Chain n-3 Polyunsaturated Fatty Acids and Risk of Hospital Diagnosis of Atrial Fibrillation in Men.
    Virtanen JK, Mursu J, Voutilainen S, Tuomainen TP.
    Circulation. 2009 Dec 8;120(23):2315-21. Epub 2009 Nov 23.
    PMID: 19933935
    doi: 10.1161/CIRCULATIONAHA.109.852657

    Conclusions- An increased concentration of long-chain n-3 PUFAs in serum, a marker of fish or fish oil consumption, may protect against AF. Serum docosahexaenoic acid concentration had the greatest impact
Matti Narkia

Serum omega-3 fatty acids are associated with variation in mood, personality and behavi... - 0 views

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    Serum omega-3 fatty acids are associated with variation in mood, personality and behavior in hypercholesterolemic community volunteers.
    Conklin SM, Harris JI, Manuck SB, Yao JK, Hibbeln JR, Muldoon MF.
    Psychiatry Res. 2007 Jul 30;152(1):1-10. Epub 2007 Mar 23.PMID: 17383013
Matti Narkia

Higher serum vitamin D concentrations are associated with longer leukocyte telomere len... - 0 views

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    Higher serum vitamin D concentrations are associated with longer leukocyte telomere length in women.
    Richards JB, Valdes AM, Gardner JP, Paximadas D, Kimura M, Nessa A, Lu X, Surdulescu GL, Swaminathan R, Spector TD, Aviv A.
    Am J Clin Nutr. 2007 Nov;86(5):1420-5.
    PMID: 17991655
Matti Narkia

Serum 25-hydroxyvitamin D levels in vitamin D-insufficient hip fracture patients after ... - 0 views

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    Serum 25-hydroxyvitamin D levels in vitamin D-insufficient hip fracture patients after supplementation with ergocalciferol and cholecalciferol.
    Glendenning P, Chew GT, Seymour HM, Gillett MJ, Goldswain PR, Inderjeeth CA, Vasikaran SD, Taranto M, Musk AA, Fraser WD.
    Bone. 2009 Nov;45(5):870-5. Epub 2009 Jul 23.
    PMID: 19631774
    doi:10.1016/j.bone.2009.07.015

    Cholecalciferol supplementation resulted in a 31% greater increase in total HPLC-measured 25OHD (p=0.010) and 52% greater rise in RIA-measured 25OHD (p<0.001) of supplementation dose with than ergocalciferol equivalent an>0.05). In vitamin D-insufficient hip fracture patients, supplementation with cholecalciferol 1000 IU/day for three months was more effective in increasing serum 25OHD than an equivalent dose of ergocalciferol. However, the lack of difference in PTH lowering between calciferol treatments raises questions about the biological importance of this observation.
Matti Narkia

Optimal Serum 25-Hydroxyvitamin D Levels for Multiple Health Outcomes - SpringerLink - ... - 0 views

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    Optimal serum 25-hydroxyvitamin D levels for multiple health outcomes.
    Bischoff-Ferrari HA.
    Adv Exp Med Biol. 2008;624:55-71. Review.
    PMID: 18348447
    DOI: 10.1007/978-0-387-77574-6_5

    Recent evidence suggests that higher vitamin D intakes beyond current recommendations may be associated with better health outcomes. In this chapter, evidence is summarized from different studies that evaluate threshold levels for serum 25(OH)D levels in relation to bone mineral density (BMD), lower extremity function, dental health, risk of falls, admission to nursing home, fractures, cancer prevention and incident hypertension. For all endpoints, the most advantageous serum levels for 25(OH)D appeared to be at least 75 nmol/l (30 ng/ml) and for cancer prevention, desirable 25(OH)D levels are between 90-120 nmol/l (36-48 ng/ml). An intake of no less than 1000IU (25 meg) of vitamin D3 (cholecalciferol) per day for all adults may bring at least 50% of the population up to 75 nmol/l. Thus, higher doses of vitamin D are needed to bring most individuals into the desired range. While estimates suggest that 2000 IU vitamin D3 per day may successfully and safely achieve this goal, the implications of 2000 IU or higher doses for the total adult population need to be addressed in future studies.
Matti Narkia

Serum 25-hydroxyvitamin D and colon cancer: eight-year prospective study. - [Lancet. 19... - 0 views

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    Serum 25-hydroxyvitamin D and colon cancer: eight-year prospective study.
    Garland CF, Comstock GW, Garland FC, Helsing KJ, Shaw EK, Gorham ED.
    Lancet. 1989 Nov 18;2(8673):1176-8.
    PMID: 2572900

    Blood samples taken in 1974 in Washington County, Maryland, from 25 620 volunteers were used to investigate the relation of serum 25-hydroxyvitamin D (25-OHD) with subsequent risk of getting colon cancer. 34 cases of colon cancer diagnosed between August, 1975, and January, 1983, were matched to 67 controls by age, race, sex, and month blood was taken. Risk of colon cancer was reduced by 75% in the third quintile (27-32 ng/ml) and by 80% in the fourth quintile (33-41 ng/ml) of serum 25-OHD. Risk of getting colon cancer decreased three-fold in people with a serum 25-OHD concentration of 20 ng/ml or more. The results are consistent with a protective effect of serum 25-OHD on colon cancer.
Matti Narkia

Serum 25-hydroxyvitamin D status of vegetarians, partial vegetarians, and nonvegetarian... - 0 views

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    Serum 25-hydroxyvitamin D status of vegetarians, partial vegetarians, and nonvegetarians: the Adventist Health Study-2.
    Chan J, Jaceldo-Siegl K, Fraser GE.
    Am J Clin Nutr. 2009 May;89(5):1686S-1692S. Epub 2009 Apr 1.
    PMID: 19339396

    Conclusions: s25(OH)D concentrations were not associated with vegetarian status. Other factors, such as vitamin D supplementation, degree of skin pigmentation, and amount and intensity of sun exposure have greater influence on s25(OH)D than does diet.
Matti Narkia

Association between serum 25(OH)D concentrations and bone stress fractures in Finnish y... - 0 views

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    Association between serum 25(OH)D concentrations and bone stress fractures in Finnish young men.
    Ruohola JP, Laaksi I, Ylikomi T, Haataja R, Mattila VM, Sahi T, Tuohimaa P, Pihlajamäki H.
    J Bone Miner Res. 2006 Sep;21(9):1483-8.
    doi: 10.1359/jbmr.060607

    Conclusions: A lower level of serum 25(OH)D concentration may be a generally predisposing element for bone stress fractures. Considering the obvious need of additional vitamin D in prevention of stress fractures, the effects of vitamin D fortification of foods and supplementation will be subjects of interest for future research
    PMID: 16939407
Matti Narkia

Low serum 25-hydroxyvitamin D concentrations and secondary hyperparathyroidism in middl... - 0 views

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    Low serum 25-hydroxyvitamin D concentrations and secondary hyperparathyroidism in middle-aged white strict vegetarians.
    Lamberg-Allardt C, Kärkkäinen M, Seppänen R, Biström H.
    Am J Clin Nutr. 1993 Nov;58(5):684-9.
    PMID: 8237875

    In conclusion, white strict vegetarians are at risk of vitamin D deficiency, at least in the winter, primarily because of a low dietary vitamin D intake, despite a normal sunlight exposure in summer. Low serum 25(OH)D concentrations are accompanied by high S-iPTH concentrations, which also are affected by a low calcium intake. The effect of these changes on bone health remains to be evaluated.
Matti Narkia

Strategies to Improve Vitamin D Status in Northern European Children: Exploring the Mer... - 0 views

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    Strategies to improve vitamin D status in northern European children: exploring the merits of vitamin D fortification and supplementation.
    Tylavsky FA, Cheng S, Lyytikäinen A, Viljakainen H, Lamberg-Allardt C.
    J Nutr. 2006 Apr;136(4):1130-4.
    PMID: 16549494
Matti Narkia

Vitamin D Status and the Risk of Lung Cancer: A Cohort Study in Finland - Cancer Epidem... - 0 views

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    Vitamin D status and the risk of lung cancer: a cohort study in Finland.
    Kilkkinen A, Knekt P, Heliövaara M, Rissanen H, Marniemi J, Hakulinen T, Aromaa A.
    Cancer Epidemiol Biomarkers Prev. 2008 Nov;17(11):3274-8.
    PMID: 18990771v

    In conclusion, although there was no overall association between vitamin D and lung cancer risk, women and young participants with a higher level of vitamin D were observed to have a lower lung cancer risk. Although experimental data support the suppressing effect of vitamin D on the development of lung cancer, large epidemiologic studies from different populations with repeated measurements of vitamin D are warranted to confirm this finding. (Cancer Epidemiol Biomarkers Prev 2008;17(11):3274-8)
Matti Narkia

Serum Vitamin D and Risk of Pancreatic Cancer in the Prostate, Lung, Colorectal, and Ov... - 0 views

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    Serum vitamin D and risk of pancreatic cancer in the prostate, lung, colorectal, and ovarian screening trial.
    Stolzenberg-Solomon RZ, Hayes RB, Horst RL, Anderson KE, Hollis BW, Silverman DT.
    Cancer Res. 2009 Feb 15;69(4):1439-47. Epub 2009 Feb 10.
    PMID: 19208842
Matti Narkia

Estimates of optimal vitamin D status. - Osteoporos Int. 2005 Jul;16(7):713-6. - Spring... - 0 views

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    Estimates of optimal vitamin D status.
    Dawson-Hughes B, Heaney RP, Holick MF, Lips P, Meunier PJ, Vieth R.
    Osteoporos Int. 2005 Jul;16(7):713-6. Epub 2005 Mar 18.
    PMID: 15776217
Matti Narkia

Vitamin D serum levels and allergic rhinitis. - Wiley InterScience :: Article :: HTML F... - 0 views

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    Vitamin D serum levels and allergic rhinitis.
    Wjst M, Hyppönen E.
    Allergy. 2007 Sep;62(9):1085-6.
    PMID: 17686112 DOI:
    10.1111/j.1398-9995.2007.01437.x
Matti Narkia

Association between serum 25(OH)D and death from prostate cancer - British Journal of C... - 0 views

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    Association between serum 25(OH)D and death from prostate cancer.
    Tretli S, Hernes E, Berg JP, Hestvik UE, Robsahm TE.
    Br J Cancer. 2009 Feb 10;100(3):450-4. Epub 2009 Jan 20.
    PMID: 19156140
    doi:10.1038/sj.bjc.6604865

    The serum level of 25(OH)D may be involved in disease progression and is a potential marker of prognosis in patients with prostate cancer.
Matti Narkia

Effects of 1 and 3 g cinnamon on gastric emptying, satiety, and postprandial blood gluc... - 0 views

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    Effects of 1 and 3 g cinnamon on gastric emptying, satiety, and postprandial blood glucose, insulin, glucose-dependent insulinotropic polypeptide, glucagon-like peptide-1, and ghrelin concentrations in healthy subjects.
    Hlebowicz J, Hlebowicz A, Lindstedt S, Björgell O, Höglund P, Holst JJ, Darwiche G, Almér LO.
    Am J Clin Nutr. 2009 Jan 21. [Epub ahead of print]
    PMID: 19158209
    doi:10.3945/ajcn.2008.26807
Matti Narkia

Serum ω-3 fatty acids are associated with variation in mood, personality and ... - 0 views

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    Conklin SM, Harris JI, Manuck SB, Yao JK, Hibbeln JR, Muldoon MF.
    Serum omega-3 fatty acids are associated with variation in mood, personality and behavior in hypercholesterolemic community volunteers.
    Psychiatry Res. 2007 Jul 30;152(1):1-10. Epub 2007
Matti Narkia

JAMA -- Effects of a Dietary Portfolio of Cholesterol-Lowering Foods vs Lovastatin on S... - 0 views

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    Jenkins DJ, Kendall CW, Marchie A, Faulkner DA, Wong JM, de Souza R, Emam A, Parker TL, Vidgen E, Lapsley KG, Trautwein EA, Josse RG, Leiter LA, Connelly PW. Effects of a dietary portfolio of cholesterol-lowering foods vs lovastatin on serum lipids and
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