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Plasma selenium, manganese superoxide dismutase, and intermediate- or high-risk prostate cancer. Chan JM, Oh WK, Xie W, Regan MM, Stampfer MJ, King IB, Abe M, Kantoff PW. J Clin Oncol. 2009 Aug 1;27(22):3577-83. Epub 2009 Jun 15. PMID: 19528373 DOI: 10.1200/JCO.2008.18.8938 Conclusion: These data suggest that the relationship between circulating selenium levels at diagnosis and prognostic risk of prostate cancer is modified by SOD2 genotype and indicate caution against broad use of selenium supplementation for men with prostate cancer.

Conclusions From a panel of twenty three plant extracts, some one dozen exhibit high or satisfactory anti-collagenase or anti-elastase activities, with nine having inhibitory activity against both enzymes. These included white tea which was found to have very high phenolic content, along with high TEAC and SOD activities Anti-collagenase, anti-elastase and anti-oxidant activities of extracts from 21 plants. Thring TS, Hili P, Naughton DP. BMC Complement Altern Med. 2009 Aug 4;9(1):27. [Epub ahead of print] PMID: 19653897 doi:10.1186/1472-6882-9-27

Docosahexaenoic acid inhibits superoxide dismutase 1 gene transcription in human cancer cells: the involvement of peroxisome proliferator-activated receptor alpha and hypoxia-inducible factor-2alpha signaling. Tuller ER, Beavers CT, Lou JR, Ihnat MA, Benbrook DM, Ding WQ. Mol Pharmacol. 2009 Sep;76(3):588-95. Epub 2009 Jun 15. PMID: 19528198

Effect of stable fish oil on arterial thrombogenesis, platelet aggregation, and superoxide dismutase activity. Chen LY, Jokela R, Li DY, Bavry AA, Sandler H, Sjöquist M, Saldeen T, Mehta JL. J Cardiovasc Pharmacol. 2000 Mar;35(3):502-5. Erratum in: J Cardiovasc Pharmacol 2000 May;35(5):829. Bowry A [corrected to Bavry AA]. PMID: 10710138

"MedWire News: High levels of selenium in the blood may worsen prostate cancer in some men who already have the disease, results of a US study suggest. In recent years, selenium supplements have been promoted as a means of preventing prostate cancer, largely based on observational studies that found higher prostate cancer incidence and mortality in geographical areas that are naturally low in selenium, compared with in those that are naturally high in the mineral. However, the current research findings suggest that "if you already have prostate cancer, it may be a bad thing to take selenium," said study researcher Dr Philip Kantoff, from the Dana-Farber Cancer Institute in Boston, Massachusetts, USA."