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Nathan Goodyear

JAMA Network | Archives of General Psychiatry | Depressive Symptoms, Vascular Disease, ... - 0 views

archpsyc.jamanetwork.com/article.aspx

dementia MCI mild cognitive impairment psychiatry vascular disease CVD cardiovascular health

shared by Nathan Goodyear on 02 Oct 12 - No Cached
  • Nathan Goodyear on 02 Oct 12
     
    dementia and depression associated with vascular disease
Nathan Goodyear

Homocysteine, folate, methylation, and monoamine metabolism in depression -- Bottiglier... - 0 views

jnnp.bmj.com/228

homocysteine depression methylation Folate 5-MTHF Folic Acid psychiatry neurology

shared by Nathan Goodyear on 26 Jun 12 - No Cached
  • Nathan Goodyear on 26 Jun 12
     
    elevated homocysteine associated with a 2 x higher incidence of depression versus those with low homocysteine.  Methylation plays a role in depression.
Nathan Goodyear

PsychiatryOnline | American Journal of Psychiatry | S-Adenosyl Methionine (SAMe) Augmen... - 0 views

ajp.psychiatryonline.org/article.aspx

SAMe SSRI depression major depression psychiatry

shared by Nathan Goodyear on 25 Jun 12 - No Cached
  • Nathan Goodyear on 25 Jun 12
     
    SAMe, in SSRI non-responders, resulted in a 46.1% response and a 35.8% remission compared to placebo.
Nathan Goodyear

Neuroendocrine disorders after... [J Neurol Neurosurg Psychiatry. 2008] - PubMed - NCBI - 0 views

www.ncbi.nlm.nih.gov/...18559460

PTHP traumatic brain injury TBI neuroendocrine post-traumatic hypopituitarism brain injury neurology hormone hormones pituitary hypothalamus psychiatry

shared by Nathan Goodyear on 09 Jul 12 - No Cached
  • Nathan Goodyear on 09 Jul 12
     
    The majority of people with PTHP after TBI remain undiagnosed.  The current thought, is that 25% of those with TBI have at least one pituitary hormone deficiency.  It does not have to be total pituitary failure.  Deficiencies can be isolated.
Nathan Goodyear

Arch Gen Psychiatry -- Abstract: Trajectories of Depression Severity in Clinical Trials... - 0 views

archpsyc.ama-assn.org/...1227

depression psychiatry SSRI therapy treatment cymbalta duloxetine non-resonders

shared by Nathan Goodyear on 10 Dec 11 - No Cached
  • Nathan Goodyear on 10 Dec 11
     
    amazingly, up to 20% of patents with depression do worse on anti-depressant therapy (SSRI).  These are labeled non-responders, but when compared to placebo, the difference was significant.  Maybe, we should check their neurotransmitters first? 
Nathan Goodyear

J Clin Psychiatry / Document Archive - 0 views

article.psychiatrist.com/dao_1-login.asp

psychiatry depression antidepressants placebo SSRI

shared by Nathan Goodyear on 13 Jan 12 - No Cached
  • This trial of urban MDD patients failed to confirm that either active treatment was better than placebo
  • Nathan Goodyear on 13 Jan 12
     
    study reveals that antidepressants no better than placebo. This study was sponsored by the National Institute of Mental Health.  
Nathan Goodyear

Does stress damage the brain? [Biol Psychiatry. 1999] - PubMed - NCBI - 1 views

www.ncbi.nlm.nih.gov/...10202566

stress hippocampus brain atrophy serotonin PTSD psychiatry damage

shared by Nathan Goodyear on 07 Feb 12 - No Cached
  • Nathan Goodyear on 07 Feb 12
     
    stress results in shrinkage of the hippocampus of the brain.  This would result in deficiency in serotonin and thus contribute to many of the symptoms found in those with PTSD.
Nathan Goodyear

Primary Psychiatry: The Neuroendocrinology of Posttraumatic Stress Disorder: New Direct... - 0 views

www.primarypsychiatry.com/...articledetail.aspx

PTSD neuroendocrinology post-traumatic stress disorder psychiatry

shared by Nathan Goodyear on 03 Feb 12 - No Cached
  • Nathan Goodyear on 03 Feb 12
     
    Neuroendocrinology of PTSD.
Nathan Goodyear

Hypocortisolism and increased glucocorticoid... [Biol Psychiatry. 2004] - PubMed - NCBI - 0 views

www.ncbi.nlm.nih.gov/...15039004

PTSD post-traumatic stress disorder low cortisol LPS IL-6 TNF-alpha psychiatry

shared by Nathan Goodyear on 03 Feb 12 - No Cached
  • Nathan Goodyear on 03 Feb 12
     
    low cortisol and elevated LPS, IL-6, and TNF-alpha found in people with PTSD.
Nathan Goodyear

PsychiatryOnline | American Journal of Psychiatry | CSF Norepinephrine Concentrations i... - 0 views

ajp.psychiatryonline.org/article.aspx

CSF norepinephrine catecholamines PTSD plasma blood serum trauma stress psychiatry disorder

shared by Nathan Goodyear on 07 Feb 12 - No Cached
  • Nathan Goodyear on 07 Feb 12
     
    CSF norepinephrine levels found to be elevated in those with PTSD.  This is one of the few, if not only study, that has looked at epinephrine concentrations in PTSD.  Plasma norepinephrine levels were found to not be associated with PTSD.
Nathan Goodyear

The natural history of neuroendocrine change... [Biol Psychiatry. 2007] - PubMed - NCBI - 0 views

www.ncbi.nlm.nih.gov/...17624319

saliva salivary testing cortisol PTSD catecholamines stress psychiatry

shared by Nathan Goodyear on 15 Nov 11 - No Cached
  • Nathan Goodyear on 15 Nov 11
     
    salivary evaluation of cortisol levels in children after MVA reveals slow normalization of elevated cortisol over time (6-18 months), yet catecholamines stay elevated
Nathan Goodyear

ScienceDirect - Psychiatry Research : High reverse T3 levels in manic and unipolar depr... - 0 views

www.sciencedirect.com/science

reverse psychiatry t3

shared by Nathan Goodyear on 08 Mar 11 - No Cached
  • measurement of reverse T3 levels as a potential tool in differential diagnosis of affective disorders
  • Nathan Goodyear on 08 Mar 11
     
    reverse T3 tool in affective disorders
Nathan Goodyear

Heart-brain medicine: Update 2008 - 0 views

www.ccjm.org/...S5.full

neurology inflammation psychiatry psychiatric disease CVD cardiovascular depression PTSD

shared by Nathan Goodyear on 01 Oct 12 - No Cached
  • Nathan Goodyear on 01 Oct 12
     
    It does appear that medicine is moving in the direction of a non-linear approach to disease.  This brief review discusses the early analysis of the relationship of psychiatric conditions, inflammation, and cardiovascular disease.
Nathan Goodyear

Omega 3/6 fatty acids for reading in children: a randomized, double-blind, placebo-cont... - 0 views

onlinelibrary.wiley.com/...abstract

omega 3 omega-3 omega-6 brain children reading

shared by Nathan Goodyear on 19 Sep 16 - No Cached
  • Nathan Goodyear on 19 Sep 16
     
    Omega 3/6 supplementation in a 1:1 ration in children improved reading skills in 3 months.
Nathan Goodyear

Testosterone Gel Supplementation for Men With Refractory Depression: A Randomized, Plac... - 0 views

ajp.psychiatryonline.org/...appi.ajp.160.1.105

depression low T low Testosterone male hormones Testosterone Testosterone therapy

shared by Nathan Goodyear on 09 Jan 17 - No Cached
  • Nathan Goodyear on 09 Jan 17
     
    study that looked at men with refractory depression symptoms on depression meds with low Testosterone finds Testosterone therapy improved depression symptoms.
Nathan Goodyear

Access : Blockade of the KATP channel Kir6.2 by memantine represents a novel mechanism ... - 0 views

www.nature.com/...mp2016187a.html

alzheimer's disease Alzheimer's brain insulin diabetes disease

shared by Nathan Goodyear on 02 Dec 16 - No Cached
  • Nathan Goodyear on 02 Dec 16
     
    Study of memantine finds effect on insulin is the same in the brain as in the pancreas.  In essence, Alzheimer's disease, is in part, a diabetes of the brain disease.
Nathan Goodyear

Molecular Psychiatry - Estrogen-dependent association of HDAC4 with fear in female mice... - 0 views

www.nature.com/...mp2016250a.html

hormones estrogen brain stress PTSD

shared by Nathan Goodyear on 01 Feb 17 - No Cached
  • Nathan Goodyear on 01 Feb 17
     
    New study suggests estrogen may protect a woman's brain at times of stress.
Nathan Goodyear

Association between patient beliefs regard... [J Clin Psychiatry. 2011] - PubMed - NCBI - 0 views

www.ncbi.nlm.nih.gov/...22053942

depression placebo SSRI anti-depressants

shared by Nathan Goodyear on 12 Jan 12 - No Cached
  • Patient beliefs regarding treatment may have a stronger association with clinical outcome than the actual medication received
  • Nathan Goodyear on 12 Jan 12
     
    study reveals that the benefit of the anti-depressant is "placebo"
Nathan Goodyear

Are antidepressants as effective as claimed... [Can J Psychiatry. 2007] - PubMed - NCBI - 0 views

www.ncbi.nlm.nih.gov/...17375864

depression antidepressants Dr. Moncrieff SSRI

shared by Nathan Goodyear on 13 Jan 12 - No Cached
  • Nathan Goodyear on 13 Jan 12
     
    Editorial from Dr. Moncrieff.  The title of the editorial tells you everything you need to know.  
Nathan Goodyear

PsychiatryOnline | American Journal of Psychiatry | Delayed-Onset Posttraumatic Stress ... - 0 views

ajp.psychiatryonline.org/article.aspx

delayed-PTSD delayed PTSD

shared by Nathan Goodyear on 04 Feb 12 - No Cached
  • Nathan Goodyear on 04 Feb 12
     
    delayed PTSD
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