Inflammation is the most predominant feature during the early (relaping) phases of the disease and declines with aging of the patients and disease duration
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Boswellia carterii Extract Inhibits TH1 Cytokines and Promotes TH2 Cytokines In Vitro - 0 views
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Frankincense shown to have immunomodulatory function. Boswellia carterii shown to inhibit Th1 cytokines.
Endogenous Estrogen Regulation of Inflammatory Arthritis and Cytokine Express... - 0 views
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this study looked at estrogen in rheumatoid arthritis in mice. They found an anti-inflammatory effect of estrogen in men through ER-alpha. This is in contrast to other studies. Maybe the immunomodulatory effects of estrogen is, in part, through which receptors are activated.
Inhibition of tumor growth and metastasis in association with modification of immune re... - 0 views
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Germanium compounds found to reduced tumor growth and potentiated tumor growth in cell culture model via immunomodulatory mechanism.
Mistletoe and Immunomodulation: Insights and Implications for Anticancer Therapies - 0 views
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Mistletoe increases CD4:CD8 due to increase in Th1 but decrease in Treg; also increase in NK cells. Very important immunomodulatory effect.
Thymosin alpha 1: A comprehensive review of the literature - 0 views
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Awesome review article on TA-1 and its broad immunomodulatory effects, i.e. increase IL-1, IFN-gamma, increase dendritic cell activity, inhibition of tumor growth…
The molecular basis of neurodegeneration in multiple sclerosis - 0 views
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anti-inflammatory or immunomodulatory treatments are effective in the relapsing stage, but the benefit is lost when the patients have entered the progressive phase
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in the process of oligodendrocyte destruction and demyelination in MS lesions iron is liberated from its intracellular ferritin bound stores into the extracellular space, where it is taken up by microglia and macrophages and again stored together with ferritin. When this happens in MS lesions in an environment, where free radicals are produced by oxidative burst, iron can be liberated from ferritin and transformed into reactive Fe++[114], which reacts with hydrogen peroxide to generate highly reactive hydroxyl radicals [36] and thus amplifies oxidative damage and associated cellular injury
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Very nice review of the neurodegenerative process in MS.
Immunomodulatory effects of Vitamin D in multiple sclerosis - 0 views
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Vitamin D has an important immunomodulating role in MS. Vitamin D increases Treg cells and decreases IL-6, but more importantly IL-17.
Interleukin‐2 enhances the natural killer cell response to Herceptin‐coated H... - 1 views
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administration of low‐dose IL‐2 results in expansion of a CD3– / CD56+ NK cell population in patients with advanced cancer
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approximately 20 % will overexpress theHer2 / neu proto‐oncogene
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In breast cancer, Her2 / neu overexpression is associated with a worse histologicalgrade, decreased relapse‐free and overall survival periods, and altered sensitivity to chemotherapeutic regimens
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low dose IL-2 found to expand NK levels in conjuction in with herceptin in HER-2 positive breast cancer cell lines.
Long-Term Immunomodulatory Effects of a Mediterranean Diet in Adults at High ... - 0 views
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Mediterranean diet found to reduce hsCRP, IL-6, TNF-alpha, and MCP in high-risk adults out to 5 years! This study compared the Mediterranean diet to a low fat diet.