ibuprofen provided no reduction in muscle damage/soreness in 29 ultra marathoners. However, LPS, CRP, IL-6, IL-10, IL-8, IL-1ra, GSF, MCP-1, and MIP-1beta were increased in the ibuprofen group. TNF-alpha was unaffected.
low sensitivity CRP associated with increased short-term and long-term mortality in hospitalized patients. Also associated with a 28 fold increase in cancer mortality.
Study finds that declining Testosterone levels and increasing TNF-alpha and CRP are associated with shorter end-stage cancer survival. Testosterone is not the same in men and women. The effects on inflammatory cytokines are different. This study should be divided into women and men to better differentiate these effects.
Men with hypogonadism, low T, Testosterone therapy reduced IL-1beta, TNF-alph, and CRP. In addition, BMI and waist circumference was reduced. Leptin and insulin decreased as well.
Six years of Testosterone therapy in men with obesity, low T, and type II Diabetes was found to decrease waist circumference, decrease weight, decrease fasting glucose, decrease in HgbA1c and improved systolic/diastolic blood pressure, lipids, CRP, and liver enzymes.
Though, obesity is associated with increasing SHBG, inflammation (which is typically elevated in obesity) is negatively associated with SHBG. CRP was used to evaluate inflammation in this study of obese men. Testosterone was also negatively associated with inflammation in these men.
inflammation negatively associated with SHBG in post menopause women. Interestingly, Estradiol was found to be positively associated. The inflammatory cytokines evaluated were CRP and IL-6.
Only abstract available here but higher fish intake associated with a decrease in CRP, IL-6, TNF-alpha, amyloid A and WBC; restated, higher fish intake associated with a reduction of inflammation