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Nathan Goodyear

http://shammer-irsc.weebly.com/uploads/1/9/8/6/19866071/ibuprofen_use_endotoxemia_inxam... - 0 views

shammer-irsc.weebly.com/...ation_and_plasma_cytokines.pdf

ibuprofen marathons exercise ultra-marathons elite athletes endurance training runners running inflammation CRP cytokines

shared by Nathan Goodyear on 09 Jan 15 - No Cached
  • Nathan Goodyear on 09 Jan 15
     
    ibuprofen provided no reduction in muscle damage/soreness in 29 ultra marathoners.  However, LPS, CRP, IL-6, IL-10, IL-8, IL-1ra, GSF, MCP-1, and MIP-1beta were increased in the ibuprofen group.  TNF-alpha was unaffected.
Nathan Goodyear

https://www.cayugamed.org/docs/Nutrition_Update_for_the_Ultraendurance_Athlete%208.pdf - 0 views

www.cayugamed.org/...Ultraendurance_Athlete%208.pdf

endurance athletes endurance exercise nutrition athletes athlete

shared by Nathan Goodyear on 10 Jan 15 - No Cached
  • Nathan Goodyear on 10 Jan 15
     
    Nutrition for ultra endurance.  To be read.
Nathan Goodyear

Dysnatremia predicts a delayed recovery in collapsed ultramarathon ... - PubMed - NCBI - 0 views

www.ncbi.nlm.nih.gov/...17620783

hyponatremia hypernatremia ultramarathon runners endurance athletes endurance exercise IV fluids athletes

shared by Nathan Goodyear on 27 Jan 15 - No Cached
  • Nathan Goodyear on 27 Jan 15
     
    The majority of ultra marathon runners deal with hypernatremia versus hyponatremia.  The majority were normonatremic.  Intravenous fluids can more rapidly resolve hypernatremia versus oral liquids and serves as useful means to reduce hypernatremia when oral liquids proves intolerable.
Nathan Goodyear

Exercise-induced right ventricular dysfunction and structural remodelling in endurance ... - 0 views

eurheartj.oxfordjournals.org/...998

endurance athletes training heart health injury

shared by Nathan Goodyear on 09 Jan 15 - No Cached
  • In a cohort of well-trained athletes, we demonstrated that intense endurance exercise causes an acute reduction in RV function that increases with race duration and correlates with increases in biomarkers of myocardial injury
  • no relationship between LV function and biomarker levels
  • focal gadolinium enhancement and increased RV remodelling were more prevalent in those athletes with a longer history of competitive sport, suggesting that repetitive ultra-endurance exercise may lead to more extensive RV change and possible myocardial fibrosis
  • ...22 more annotations...
  • he cardiac impact of both acute and cumulative exercise is greatest on the RV.
  • Greater reductions in RV function occurred in those athletes competing for a longer duration, suggesting that the heart has a finite capacity to maintain the increased work demands of exercise
  • We enrolled elite and subelite athletes and found a significant association between fitness (VO2max) and the reduction in post-race RVEF
  • Previous investigators have documented reductions in RV function in less trained subjects over the marathon distance
  • cardiac injury is greatest in the least trained
  • Even after many years of detraining, cardiac dilation may not completely regress in elite athletes
  • The focus on well-trained athletes may be of particular relevance, given that they perform exercise of highest intensity and duration most frequently, and, thus, may be at a greater risk of cumulative injury.
  • The lack of correlation between increases in troponin and changes in LV function seen in this study has been previously interpreted as evidence that post-exercise elevations in cardiac biomarkers are benign.
  • a significant correlation between changes in RVEF and post-race biomarker levels and this relationship was even stronger in the athletes who completed the race of longest duration, the ultra-triathlon
  • It has been demonstrated that ventricular load increases with exercise intensity and is greater for the RV than the LV,29 thus potentially explaining why the RV is more susceptible to fatigue after prolonged exercise.
  • BNP release during intense exercise is associated with greater relative increases in RV systolic pressures, but not LV pressures
  • BNP may provide a measure of both acute RV load and the resultant fatigue which occurs when this load is sustained
  • The correlations with RVEF, but not LVEF, provide further evidence of the differential effects of intense exercise on RV and LV function
  • This study demonstrates, for the first time, an association between endurance exercise of increasing duration and structural, functional, and biochemical markers of cardiac dysfunction in highly trained athletes
  • Functional abnormalities were confined to the RV and were largely reversible 1 week following the event
  • there remained a significant minority of athletes in whom there was evidence of myocardial fibrosis in the interventricular septum
  • RV abnormalities may be acquired through cumulative bouts of intense exercise and provides direction for prospective investigations aimed at elucidating whether extreme exercise may promote arrhythmias in some athletes.
  • the acute injury and chronic remodelling of the myocardium both disproportionately affect the RV and it remains possible that the two are linked.
  • focal DGE was confined to the interventricular septum and commonly at the site of RV attachment
  • emerging evidence that intense endurance exercise may be associated with an excess in arrhythmic disorders, the mechanisms for which remain unexplained
  • RVEF (and not LVEF) was reduced in athletes with complex ventricular arrhythmias when compared with healthy athletes and non-athletes without arrhythmias
  • it is premature to conclude that these changes may represent a proarrhythmic substrate
  • Nathan Goodyear on 09 Jan 15
     
    Study finds endurance racing results in reduce Right ventricle ejection fraction even in elite athletes.  This post-race RVEF reduction is associated with VO2max.
Nathan Goodyear

Serum biochemistry and morbidity among runners presenting for medic... - PubMed - NCBI - 0 views

www.ncbi.nlm.nih.gov/...17620786

ultra-marathons endurance athletes IV fluids hyponatremia

shared by Nathan Goodyear on 27 Jan 15 - No Cached
  • Nathan Goodyear on 27 Jan 15
     
    Study looked at 9 athletes that were treated with IV fluids and found no significant morbidity with exercise associated hyponatremia.
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