Skip to main content

Home/ Dr. Goodyear/ Group items tagged cognition

Rss Feed Group items tagged

Filter: All | Bookmarks | Topics Simple Middle
Nathan Goodyear

JAMA Network | JAMA | Conjugated Equine Estrogens and Incidence of Probable D... - 0 views

jama.jamanetwork.com/article.aspx

premarin memory dementia HRT HT hormone therapy hormone hormones women brain WHI MPA medroxyprogesterone acetate

shared by Nathan Goodyear on 06 Aug 13 - No Cached
  • Nathan Goodyear on 06 Aug 13
     
    This was the WHI review of data as it pertains to dementia and cognitive decline in women.  The take home here is that the data provides little evidence for premarin with or without medroxyprogesterone acetate in > 65 for prevention of dementia.  However, this is in women > 65 and studies show that younger women do indeed receive benefit, especially in those with early ovary removal.  Another point here, MPA (medroxyprogesterone acetate) increases cognitive decline.  Just don't take MPA, it is a bad drug all the way around!
Nathan Goodyear

Nutrition Journal | Full text | The emerging role of dietary fructose in obesity and co... - 0 views

www.nutritionj.com/...114

nutrition fructose obesity cognitive decline cognition

shared by Nathan Goodyear on 19 Sep 13 - No Cached
  • Nathan Goodyear on 19 Sep 13
     
    Article links Fructose, to obesity and cognitive decline.
Nathan Goodyear

https://endo.confex.com/endo/2014endo/webprogram/Paper14285.html - 0 views

endo.confex.com/...Paper14285.html

statin statins statin therapy brain cognition metabolic syndrome metabolic syndrome memory

shared by Nathan Goodyear on 19 Jul 14 - No Cached
  • Nathan Goodyear on 19 Jul 14
     
    Statin use found to be associated with cognitive decline.  The authors defined use as long-term, though 2 years of use was found to be associated with decline.   interestingly, metabolic syndrome was not found to be associated with cognitive decline.
Nathan Goodyear

The combined effects of exercise and foods in preventing neurological and cognitive dis... - 0 views

www.ncbi.nlm.nih.gov/...PMC3258093

diet nutrition exercise BDNF omega-3 omega 3 n-3 brain derived neurotrophic factor curcumin polyphenols neuroplasticity memory sugar saturated fats

shared by Nathan Goodyear on 01 Nov 13 - No Cached
  • The most prevalent types of cognitive impairments include disturbances in attention and learning and memory function
  • An association between BDNF and learning and memory was found when measuring the performance of rats on the Morris water maze task
  • exercise and BDNF have been associated with reducing depression and promoting cognitive enhancement.
  • ...3 more annotations...
  • In addition to reducing oxidative stress and inflammation, DHA serves to improve neuronal function by supporting synaptic membrane fluidity
  • Curcumin has also been shown to protect the hippocampus and to counteract learning impairment
  • insufficient DHA in the brain can compromise neuronal function with subsequent effects on a broad range of neurological and behavioral faculties.
  • Nathan Goodyear on 01 Nov 13
     
    diet and exercise increases BDNF.  Diets rich in omega 3, curcumin, and polyphenols increase BDNF and thus increase neuroplasticity and associated cognition.   In contrast, sugar and saturated fats in crease oxidative stress and worsened spatial learning.  This study is a review.  
Nathan Goodyear

https://www.medify.com/articles/search?pivot=condition&condition=Cognition%20Disorders&... - 0 views

www.medify.com/...search

curcumin tumeric cognition brain

shared by Nathan Goodyear on 01 Nov 13 - No Cached
  • Nathan Goodyear on 01 Nov 13
     
    list of studies to review at later date of curcumin cognition
Nathan Goodyear

Dietary Strategy to Repair Plasma Membrane After Brain Trauma - 0 views

nnr.sagepub.com/...75.full

BDNF curcumin DHA TBI concussion brain injury traumatic brain injury

shared by Nathan Goodyear on 30 Aug 15 - No Cached
  • strategies directed to preserve phospholipids in the plasma membrane such as the use of dietary docosahexaenoic acid (C22:6n-3; DHA)5 can have beneficial effects for post-TBI recovery
  • DHA is the most abundant polyunsaturated fatty acid (PUFA) in the brain
  • Curcumin provided in the diet before TBI can reduce oxidative damage and counteract TBI-related cognitive dysfunction.
  • ...8 more annotations...
  • Our previous study indicated that n-3 fatty acids supplemented in the diet counteracted learning disability after TBI
  • There was a significant group effect on BDNF (F 4,25 = 5.229, P < .01 by ANOVA), and FPI reduced BDNF levels (50% of CTL, P < .01; Figure 1C), which was counteracted by DHA supplementation (90% of CTL, P < .05; Figure 1C). Curcumin also counteracted this reduction of BDNF
  • The combination of curcumin and DHA had a trend of greater effects in BDNF (117% of CTL; Figure 1C) compared with DHA or curcumin alone.
  • curcumin contributed to enhance the action of DHA, protecting against cognitive impairment, and these effects were associated with elevations in the BDNF receptor signaling
  • Our current results show that curcumin contributes to enhance the effects of DHA on TBI by promoting phosphorylation of the BDNF receptor TrkB in the hippocampus.
  • previous evidence indicates that curcumin10 and DHA5 counteract TBI-related learning disability by involving BDNF
  • The effects of the DHA diet and curcumin on cognitive enhancement were consistent with enhanced elevations in BDNF receptor signaling
  • effects of DHA and curcumin up to 2 weeks after TBI because this is the most critical period for the course of injury recovery because the brain is metabolically dysfunctional during this time
  • Nathan Goodyear on 30 Aug 15
     
    study that finds curcumin + DHA increased cognitive improvement after TBI within 2 weeks.  Good discussion of the proposed mechanism--increased BDNF.
Nathan Goodyear

Dietary supplementation of arachidonic and docosahexaenoic acids improves cognitive dys... - 0 views

www.ncbi.nlm.nih.gov/...16905216

essential fatty acids DHA omega 3 omega-3 arachidonic acid brain

shared by Nathan Goodyear on 20 Feb 16 - No Cached
  • Nathan Goodyear on 20 Feb 16
     
    study proposes that arachidonic acid and DHA improve cognition in individuals with age related cognition changes and organic brain damage (Alzheimer's, brain lesions...)
Nathan Goodyear

Alzheimer's Disease Clinical and Research Update for Health Care Practitioners - 0 views

www.ncbi.nlm.nih.gov/...PMC3776389

Alzheimer's disease cognition memory Alzheimers brain brain health alpha-GPC phosphatidyl serine Huperzine A choline

shared by Nathan Goodyear on 26 Sep 17 - No Cached
  • Alpha GPC, phosphatidylserine, Huperzine A, and choline show promise as nutraceutical agents for enhancing cognitive performance and slowing cognitive decline
  • Alpha GPC, also known as L-Alpha Glycerylphosphorylcholine, a naturally occurring form of choline, acts as a parasympathomimetic acetylcholine precursor and has shown promise in improving cognitive symptoms related to AD, vascular dementia, and multi-infarct dementia
  • Phosphatidylserine is a widely abundant anionic phospholipid in the human body and has been shown to improve age-related cognitive changes
  • ...2 more annotations...
  • Huperzine A (a natural cholinesterase inhibitor) has been linked to improved memory performance in elderly people with benign forgetfulness, as well as patients with AD and vascular dementia
  • Cholinesterase inhibitors have been shown to have neuroprotective properties in patients with mild [37] as well as moderate-to-advanced AD
  • Nathan Goodyear on 26 Sep 17
     
    good review of treatment for Alzheimer's, both prescription and natural.
Nathan Goodyear

Cognition, mood, and physiological concentrations of sex hormones in the early and late... - 0 views

www.pnas.org/...20290.abstract

menopause progesterone hormones brain health brain cognition women

shared by Nathan Goodyear on 13 May 16 - No Cached
  • Nathan Goodyear on 13 May 16
     
    Medical dogma tells us that menopause is simply an estrogen deficiency.  This new study points to correlation between progesterone decline and cognitive decline in menopausal women.
Nathan Goodyear

Vitamin C reduces spatial learning deficits in middle-aged and very old APP/PSEN1 trans... - 0 views

www.ncbi.nlm.nih.gov/...PMC2725435

IV vitamin C brain Alzheimer's disease dementia cognition cognitive function learning

shared by Nathan Goodyear on 08 Mar 12 - No Cached
  • Nathan Goodyear on 08 Mar 12
     
    IV vitamin C improves cognitive function in mice model.  
Nathan Goodyear

High normal plasma triglycerides are associated with preserved cognitive function in Ch... - 1 views

ageing.oxfordjournals.org/...ageing.afs033.abstract

triglyceride triglycerides cognitive function lipids neurology

shared by Nathan Goodyear on 19 Jun 12 - No Cached
  • Nathan Goodyear on 19 Jun 12
     
    Higher triglyceride levels associated with better cognitive function versus those with lower triglyceride levels in an elderly chinese population.
Nathan Goodyear

Cognition, mood, and physiological concentrations of sex hormones in the early and late... - 0 views

www.pnas.org/...1312353110.abstract

menopause women hormone hormones cognition progesterone estrogen estradiol estrone testosterone SHBG

shared by Nathan Goodyear on 19 Dec 13 - No Cached
  • Nathan Goodyear on 19 Dec 13
     
    Progesterone levels were associated with sustained verbal memory and global recognition in early menopause.  SHBG was also positively associated.  Estradiol, estrone, and testosterone were not associated with sustained global cognition in women.
Nathan Goodyear

Progesterone enhances transthyretin expressio... [J Mol Neurosci. 2011] - PubMed - NCBI - 0 views

www.ncbi.nlm.nih.gov/...20535645

progesterone Alzheimer's disease alzheimer's disease Alzheimers Transthyretin hormone hormones postmenopause women menopause

shared by Nathan Goodyear on 17 Mar 14 - No Cached
  • Nathan Goodyear on 17 Mar 14
     
    Postmenopausal cognitive decline is a common complaint.  Declining Estradiol and progesterone have been implicated, in part, to this cognitive decline.  This study finds that progesterone increases expression of Transthyretin, a protein that processes amyloid Beta protein.  This amyloid Beta protein is associated with damage found in Alzheimer's. 
Nathan Goodyear

The emerging role of dietary fructose in obesity and cognitive decline - 0 views

www.ncbi.nlm.nih.gov/...PMC3751294

obesity fructose cognitive decline

shared by Nathan Goodyear on 27 Sep 13 - No Cached
  • Nathan Goodyear on 27 Sep 13
     
    Study describes the link between fructose, obesity and cognitive decline.
Nathan Goodyear

Long-term follow-up of cognitive dysfunction... [J Inorg Biochem. 2011] - PubMed - NCBI - 0 views

www.ncbi.nlm.nih.gov/...22099155

Aluminum macrophagic myofasciitis macrophagic myofasciitis associated cognitive dysfunction MACD

shared by Nathan Goodyear on 09 Oct 13 - No Cached
  • Nathan Goodyear on 09 Oct 13
     
    Aluminum and Macrophagic myofasciitis associated cognitive dysfunction (MACD).
Nathan Goodyear

DHA dietary supplementation enhances the effects of exercise on synaptic plasticity and... - 0 views

www.ncbi.nlm.nih.gov/...PMC3208643

DHA n-3 omega 3 omega-3 fish oil cognition memory hippocampus exercise neuroplasticity BDNF brain derived neurotrophic factor lipid peroxidation

shared by Nathan Goodyear on 01 Nov 13 - No Cached
  • Nathan Goodyear on 01 Nov 13
     
    DHA enriched diet plus exercis improved cognition through a increase in brain derived neurotrophic factor (BDNF).  The result was increased neuroplasticity.  Additionally, they were shown to reduce hippocampal lipid peroxidation.
Nathan Goodyear

Curry Consumption and Cognitive Function in the Elderly - 0 views

aje.oxfordjournals.org/...898

curcumin tumeric curry cognition brain

shared by Nathan Goodyear on 01 Nov 13 - No Cached
  • Nathan Goodyear on 01 Nov 13
     
    Curcumin consumption associated with increased cognition in elderly Asians.
Nathan Goodyear

Results of the MIDAS trial: Effects of docosahexaenoic acid on physiological and safety... - 0 views

www.alzheimersanddementia.com/...abstract

omega 3 n-3 omega-3 cognition brain

shared by Nathan Goodyear on 04 Nov 13 - No Cached
  • Nathan Goodyear on 04 Nov 13
     
    no abstract available, however this study found DHA slowed age related cognitive decline at 900 mg daily.
Nathan Goodyear

Acute cognitive effects of standardised ... [Hum Psychopharmacol. 2007] - PubMed - NCBI - 0 views

www.ncbi.nlm.nih.gov/...17457961

Ginkgo biloba Ginkgo biloba phosphatidylserine cognition brain

shared by Nathan Goodyear on 07 Nov 13 - No Cached
  • Nathan Goodyear on 07 Nov 13
     
    Ginkgo biloba provides increased positive cognitive effects when combined with phosphatidylserine.
Nathan Goodyear

Fructose decreases physical activity and increases body fat without affecting hippocamp... - 0 views

www.nature.com/...srep09589.html

fructose obesity fat diet nutrition activity physical activity

shared by Nathan Goodyear on 03 Aug 15 - No Cached
  • the fructose animals gained significantly more weight than the glucose animals
  • The average liver mass of mice in the fructose treatment group was 20% heavier than for mice in the glucose group
  • The fat pads of mice consuming the fructose diet were 69% heavier than the fat pads of animals consuming the glucose diet
  • ...12 more annotations...
  • there are many studies showing that consumption of fructose in comparison to other monosaccharides results in increased de novo lipogenesis, dyslipidemia, insulin resistance, BW6, 7 and, most recently, impaired cognitive function
  • in the present study, the intake of fructose by mice was more similar to that of typical human consumption in comparison to previous studies
  • prolonged consumption of diets containing fructose (11 weeks) increased BW and body fat deposition
  • studies in humans confirm that fructose, but not glucose (when provided as 25% of energy requirements), in the context of an energy-balanced diet increases de novo lipogenesis and visceral adiposity along with dyslipidemia, decreases insulin sensitivity10, 12 and decreases in fat oxidation
  • we hypothesize that fructose may reduce voluntary energy expenditure in terms of physical activity.
  • significant reduction (~20%) in physical activity in the fructose-fed animals in comparison to glucose
  • a recent study reported that ingestion of fructose (25% energy intake, 10 weeks) in human volunteers also resulted in reduced energy expenditure in relation to a diet with the same glucose dose
  • There is certainly evidence to suggest that, for example, exercise is able to prevent dyslipidemia in healthy subjects fed a weight-maintenance high-fructose diet (30%)54, which strongly suggests a protective role of physical activity in metabolic regulation.
  • the potential negative effects of fructose in brain and cognitive function have been investigated, with a series of studies showing cognitive deficits in spatial memory and learning in adolescent and adult animals following access to a high fructose diet
  • access to both fructose and sucrose, but not glucose, results in a 40% reduction in hippocampal neurogenesis
  • Collectively these studies seem to suggest that fructose consumption can have a considerable impact on hippocampal function and learning, which is in direct contrast with what we observed.
  • the impact of fructose is apparent only in BW, liver mass and body fat, but not in cognitive measures or rates of neurogenesis
  • Nathan Goodyear on 03 Aug 15
     
    animal study finds that fructose increased liver mass, abdominal fat and decreased physical activity when compared to glucose.  The study groups were iso caloric, but one group was fed 18% fructose and the other 18% glucose.
‹ Previous 21 - 40 of 152 Next › Last »
Showing 20▼ items per page