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Prevalence and Correlates of Late-Onset Hypogonadism Among Korean Men Aged 40 Years or ... - 0 views

online.liebertpub.com/...jomh.2013.1505

hypogonadism low T Testosterone male men hormone hormones metabolic syndrome diabetes obesity age

shared by Nathan Goodyear on 08 Apr 14 - No Cached

Nathan Goodyear on 08 Apr 14

Study of Korean men finds late onset of hypogonadism to be 16.8% in their study of 1,235 men older than 40. This is a higher rate than other studies, but lower than others (38.7% in American men). The test definition of low T was set at 3.2 ng/ml. Abdominal obesity, metabolic syndrome, diabetes, and increasing age were associated with low T. Low T is clearly not a problem unique to America. It definitely appears that a decreasing Testosterone level is a marker of poor health in men.

<div class="cArrow"> </div><div class="cContentInner">Study of Korean men finds late onset of hypogonadism to be 16.8% in their study of 1,235 men older than 40. This is a higher rate than other studies, but lower than others (38.7% in American men). The test definition of low T was set at 3.2 ng/ml. Abdominal obesity, metabolic syndrome, diabetes, and increasing age were associated with low T. Low T is clearly not a problem unique to America. It definitely appears that a decreasing Testosterone level is a marker of poor health in men. </div>

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Association of Preoperative Testosterone Levels with Biochemical Failure in Men Undergo... - 0 views

online.liebertpub.com/...jomh.2013.0016

testosterone low T prostate cancer men male hormone hormones

shared by Nathan Goodyear on 08 Apr 14 - No Cached

Nathan Goodyear on 08 Apr 14

Study finds that low Testosterone preoperative is associated with increased positive surgical margins and worse staging post radical prostatectomy. Also association with a non-statistical increase in biochemical failure.

<div class="cArrow"> </div><div class="cContentInner">Study finds that low Testosterone preoperative is associated with increased positive surgical margins and worse staging post radical prostatectomy. Also association with a non-statistical increase in biochemical failure.</div>

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The expanding role of incretin-based therapies: how much should we expect? - 0 views

joe.endocrinology-journals.org/...E1.full

incretins

shared by Nathan Goodyear on 08 Apr 14 - No Cached

The incretins are peptide hormones released from the small intestine during meal absorption that stimulate insulin secretion from pancreatic β-cells and reduce excessive secretion of glucagon by pancreatic α-cells
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Nathan Goodyear on 08 Apr 14

intro to incretins

<div class="cArrow"> </div><div class="cContentInner">intro to incretins</div>

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JAMA Network | JAMA Pediatrics | Prevalence and Trends in Obesity and Severe Obesity Am... - 0 views

archpedi.jamanetwork.com/article.aspx

obesity children

shared by Nathan Goodyear on 08 Apr 14 - No Cached

Nathan Goodyear on 08 Apr 14

Trends tell a lot more than individual values. IN the battle against obesity, trends tell a sad story. Obesity rates are increasing in our children. Up to 17.2% in children. The numbers in the severe category fared the worse.

<div class="cArrow"> </div><div class="cContentInner">Trends tell a lot more than individual values. IN the battle against obesity, trends tell a sad story. Obesity rates are increasing in our children. Up to 17.2% in children. The numbers in the severe category fared the worse.</div>

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Association of fructose consumption and components... [Nutrition. 2014] - PubMed - NCBI - 0 views

www.ncbi.nlm.nih.gov/...24698343

metabolic syndrome fructose nutrition diet glucose triglycerides hypertension

shared by Nathan Goodyear on 07 Apr 14 - No Cached

Nathan Goodyear on 07 Apr 14

Fructose intake associate with increased fasting blood sugar, elevated triglycerides, and elevated systolic blood pressure--all parameters of metabolic syndrome.

<div class="cArrow"> </div><div class="cContentInner">Fructose intake associate with increased fasting blood sugar, elevated triglycerides, and elevated systolic blood pressure--all parameters of metabolic syndrome.</div>

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Aromatase and regulation of the estrogen-to... [Ann N Y Acad Sci. 2014] - PubMed - NCBI - 0 views

www.ncbi.nlm.nih.gov/...24684533

aromatase aromatase activity vitamin D estrone E1 inflammation RA rheumatoid arthritis

shared by Nathan Goodyear on 07 Apr 14 - No Cached

Nathan Goodyear on 07 Apr 14

Study looked at inflammatory markers in RA. The authors point to high aromatase activity, low androgens, and elevated estrone in synovial fluid as an indicator of a link between aromatase activity and inflammation production through E1 production. The authors also point to the 16 alpha metabolite pathway as pro-inflammatory as well. One very interesting point made by the authors is that vitamin D down regulates aromatase activity. In addition to NK-kappaB inhibition, this may be another mechanism by which vitamin D reduces inflammation.

<div class="cArrow"> </div><div class="cContentInner">Study looked at inflammatory markers in RA. The authors point to high aromatase activity, low androgens, and elevated estrone in synovial fluid as an indicator of a link between aromatase activity and inflammation production through E1 production. The authors also point to the 16 alpha metabolite pathway as pro-inflammatory as well. One very interesting point made by the authors is that vitamin D down regulates aromatase activity. In addition to NK-kappaB inhibition, this may be another mechanism by which vitamin D reduces inflammation.</div>

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Hypogonadism and Metabolic Syndrome in Nigerian Male Patients With Both Type 2 Diabetes... - 0 views

www.ncbi.nlm.nih.gov/...PMC3968985

diabetes hypertension blood pressure metabolic syndrome low T Testosterone CVD men male hormone hormones lipids dyslipidemia

shared by Nathan Goodyear on 07 Apr 14 - No Cached

Nathan Goodyear on 07 Apr 14

Asian study finds Testosterone is inversely associated with increased central obesity, increased dyslipidemia, and metabolic syndrome in me with new diagnosis of type II diabetes and hypertension. Men with metabolic syndrome, type II diabetes, and CVD must have appropriate hormone evaluation.

<div class="cArrow"> </div><div class="cContentInner">Asian study finds Testosterone is inversely associated with increased central obesity, increased dyslipidemia, and metabolic syndrome in me with new diagnosis of type II diabetes and hypertension. Men with metabolic syndrome, type II diabetes, and CVD must have appropriate hormone evaluation.</div>

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Dehydroepiandrosterone supplementati... [J Clin Endocrinol Metab. 2013] - PubMed - NCBI - 0 views

www.ncbi.nlm.nih.gov/...23824417

DHEA fat mass men male hormone hormones elderly men

shared by Nathan Goodyear on 07 Apr 14 - No Cached

Nathan Goodyear on 07 Apr 14

meta-analysis finds reduction in fat mass from DHEA in elderly men. The authors propose that it is due to the conversion to other hormones.

<div class="cArrow"> </div><div class="cContentInner">meta-analysis finds reduction in fat mass from DHEA in elderly men. The authors propose that it is due to the conversion to other hormones. </div>

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Testosterone Supplementation and Sexual Function: ... [J Sex Med. 2014] - PubMed - NCBI - 0 views

www.ncbi.nlm.nih.gov/...24697970

low T Testosterone male hypogonadism hormone hormones libido bias men

shared by Nathan Goodyear on 06 Apr 14 - No Cached

Nathan Goodyear on 06 Apr 14

Meta-analysis finds bias in industry studies versus independent studies. No surprise there. Testosterone in this meta-analysis was found to aid sexual dysfunction in men with hypogonadism.

<div class="cArrow"> </div><div class="cContentInner">Meta-analysis finds bias in industry studies versus independent studies. No surprise there. Testosterone in this meta-analysis was found to aid sexual dysfunction in men with hypogonadism.</div>

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Testosterone level and mortality in elderly men with systolic chronic heart failure - 0 views

www.ncbi.nlm.nih.gov/...PMC3739581

low T testosterone heart failure mortality congestive CHF men male hormone hormones hypogonadism

shared by Nathan Goodyear on 06 Apr 14 - No Cached

Nathan Goodyear on 06 Apr 14

Good article. Heart failure in men associated with lower Total Testosterone and estimated Free Testosterone. The severity of disease was associated with lower Testosterone levels. I wish they would have measured free levels not estimated them. Increased SHBG concentrations was associated increased CHF as well. This study found no association with mortality.

<div class="cArrow"> </div><div class="cContentInner">Good article. Heart failure in men associated with lower Total Testosterone and estimated Free Testosterone. The severity of disease was associated with lower Testosterone levels. I wish they would have measured free levels not estimated them. Increased SHBG concentrations was associated increased CHF as well. This study found no association with mortality.</div>

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