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Glyphosate inhibits CYP 450 enzymes.  The author states it well: "glyphosate enhances the damaging effects fo other food borne chemical residues and environnmental toxins.  Additionally, Glyphosate disrupts gut bacterial function in the human gut. This dysbiosis is well known to cause systemic disease, such as obesity, diabetes...

glyphosate increases ER-alpha expression and activation though this study found no evidence that glyphosate bound to ER-alpha. This makes glyphosate a endocrine disrupter.

Glyphosate, component of Roundup is well known to be an endocrine disruptor.  This rat study describes the mechanism  of disruption of the Sertoli cells resulting in male infertility.  In addition to the disruption of spermatogenesis, Glyphosate was shown to deplete glutathione levels compromising detoxification.  If that is not enough, oxidative damage marker TBARS was elevated.  

Glyphosate found to lower Testosterone in rat study.  Glyphosate is a significant xenoestrogen which acts as an endocrine disruptor.

Shock!  Glyphosphate is a xenoestrogen and promoted growth of breast cancer cells via estrogen receptors. This is only the abstract, but the glyphosate was found to "alter" the ERalpha and ERbeta expression.  These effects were found at low levels existing in the environment.

Probably one of the more disturbing aspects of glyphosate exposure. In utero exposure, lowers Testosterone levels and effects the masculinization process of the young boy.  Very disturbing.  Our boys are being altered before they are even born.

Glyphosate-based herbicides (commonly found in roundup) shown to cause damage to placenta cells.  This has major implications in infertility and pregnancy health

low exposure to glyphosate-based herbicide (round up) decreases Testosterone production by 35%.   This occurs at very low exposure levels of 1 ppm.  In a rat study, large doses causes ACUTE rat TESTICULAR TOXICITY. I think both men and women should be very careful around this chemical

Glyphosate, component of Roundup shown to disrupt Testosterone production, aromatase activity, and the androgen receptors in this male in vivo model.

Scary stat--75% of samples from air and rainfall taken in delta contaminated with glyphosate and its metabolite AMPA.  These levels were not measured in 1995 so % increase is unable to be determined.  We do know that roundup use has increased dramatically over that time frame.  

Glyophosate found to be increased in the urine of animals and humans eating GMO food products.  Interesting association that "ill" humans had higher urinary glyophosate levels.  What is defined as "ill" is left to be determined. But clearly, glyophosate is not the innocent product that we have told it was.

Glyphosate disrupts CYP450 pathways.