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Nathan Goodyear

Co-occurrence of Cardiovascular and Prothrombotic Risk Facto... : Obstetrics & Gynecology - 0 views

journals.lww.com/...ular_and_Prothrombotic.16.aspx

preeclampsia CVD cardiovascular disease cardiovascular disease obstetrics

shared by Nathan Goodyear on 21 Dec 12 - No Cached
  • Nathan Goodyear on 21 Dec 12
     
    preeclampsia should be a history marker that reveals increased cardiovascular disease (CVD).  
Nathan Goodyear

A randomized clinical trial of exercise during pregnancy to prevent gestation... - 0 views

www.ajog.org/...fulltext

exercise pregnancy gestational diabetes diabetes Obesity obstetrics

shared by Nathan Goodyear on 02 May 17 - No Cached
  • Nathan Goodyear on 02 May 17
     
    Exercise reduces Gestational Diabetes risk in Obese pregnant women.  The amount of exercise was quite limited: 30 minutes cycling for 3 days/week only. No increased risk of preterm delivery as well.
  • Open TeleShop on 17 May 17
     
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Nathan Goodyear

Sexual Function in Older Women After Oophorectomy : Obstetrics & Gynecology - 0 views

journals.lww.com/...men_After_Oophorectomy.15.aspx

sexual function sex oophorectomy ovaries gynecology women

shared by Nathan Goodyear on 21 Sep 12 - No Cached
  • Nathan Goodyear on 21 Sep 12
     
    Here is my problems with "statistics".  The statement "No significant difference in the report of sexual ideation was found..."  If you are the one women that had decreased sexual function after having your ovaries removed: isn't it comforting to know you are not statistically significant.  Come on.  Some did, and that is enough and should be considered significant.  This is a permanent change to these woman's lives and marriage.
Nathan Goodyear

Maternal 25-Hydroxyvitamin D and Preterm Birth in Twin Gesta... : Obstetrics & Gynecology - 0 views

journals.lww.com/...nd_Preterm_Birth_in.99784.aspx

vitamin D PTD preterm delivery pregnancy

shared by Nathan Goodyear on 07 Jun 13 - No Cached
  • Nathan Goodyear on 07 Jun 13
     
    vitamin D associated with increased Pre term delivery in twin pregnancies.  This is a cohort, so not the most reliable of study designs, but known that vitamin D inhibits inflammation and that this plays a role in labor...logic makes sense.
Nathan Goodyear

Cigarette smoking and hormones : Current Opinion in Obstetrics and Gynecology - 0 views

journals.lww.com/...te_smoking_and_hormones.3.aspx

smoking tobacco CYP1A1 CYP1B1 estrogen hormones estrogen metabolism estrogen metabolites

shared by Nathan Goodyear on 05 Dec 16 - No Cached
  • Epidemiologic studies worldwide have established that exposure to cigarette smoke is an important cause of estrogen deficiency.
  • Nathan Goodyear on 05 Dec 16
     
    tobacco smoke alters estrogen metabolism.  Increase in CYP1B1 and CYP1B1 are the result of tobacco smoke.
Nathan Goodyear

JAMA Network | JAMA | Evaluation of the Association of Maternal Pertussis Vaccination W... - 0 views

jama.jamanetwork.com/article.aspx

vaccine vaccines vaccinations Tdap pertussis chorioamnionitis pregnancy

shared by Nathan Goodyear on 11 May 16 - No Cached
  • Nathan Goodyear on 11 May 16
     
    Study finds no increased adverse events in Tdap in pregnant mothers; however, RR finds 19% increase in chorioamnionitis.  
Nathan Goodyear

Exercise during pregnancy in normal-weight women and risk of preterm birth: a... - 0 views

www.ajog.org/...abstract

exercise pregnancy

shared by Nathan Goodyear on 12 Jul 16 - No Cached
  • Nathan Goodyear on 12 Jul 16
     
    Exercise is not only safe in pregnancy, it is good for the pregnancy and the baby. This idea that pregnancy is a disease or a condition has got to stop; science continues to prove that is not the case.
Nathan Goodyear

Effect of Hysterectomy With Ovarian Preservation on Ovarian... : Obstetrics & Gynecology - 0 views

journals.lww.com/...h_Ovarian_Preservation.10.aspx

ovarian failure hysterectomy premature

shared by Nathan Goodyear on 01 Dec 11 - No Cached
  • Nathan Goodyear on 01 Dec 11
     
    premature ovarian failure shown to be more common post hysterectomy
Nathan Goodyear

Current Issue : Obstetrics & Gynecology - 0 views

journals.lww.com/...currenttoc.aspx

anti-depressants SSRI PMS physical symptoms

shared by Nathan Goodyear on 10 Dec 11 - No Cached
  • Nathan Goodyear on 10 Dec 11
     
    analysis of 3 clinical trials found that up to 40% of 447 women that were treated with antidepressant therapy found no benefit.  Physical symptoms were provided little, if any benefit.
Nathan Goodyear

A study to evaluate serum and urinary hormone levels following short and long term admi... - 1 views

onlinelibrary.wiley.com/...full

progesterone hormones hormone testing saliva salivary

shared by Nathan Goodyear on 03 Nov 10 - No Cached
  • Nathan Goodyear on 03 Nov 10
     
    A study to evaluate serum and urinary hormone levels following short and long term administration of two regimens of progesterone cream in postmenopausal women
Nathan Goodyear

ScienceDirect - Obstetrics & Gynecology : Salivary progesterone concentrations after tu... - 0 views

www.sciencedirect.com/science

saliva salivary testosterone progesterone tubal sterilization

shared by Nathan Goodyear on 19 Jan 11 - No Cached
  • Nathan Goodyear on 19 Jan 11
     
    salivary progesterone levels decrease after tubal sterilization
Nathan Goodyear

A comparison of saliva, plasma unconjugated and plasma total oestriol levels throughout... - 0 views

onlinelibrary.wiley.com/...abstract

saliva salivary testing estriol

shared by Nathan Goodyear on 18 Jan 11 - No Cached
  • It seems probable that measurement of salivary E3 could adequately replace that of plasma unconjugated E3 in the assessment of fetoplacental function.
  • Nathan Goodyear on 18 Jan 11
     
    salivary testing of estriol in pregnancy validated
Nathan Goodyear

Parenteral nutrition in obstetric patients. [Nutr Clin Pract. 1990] - PubMed result - 0 views

www.ncbi.nlm.nih.gov/...2117234

IV nutrition therapy pregnancy

shared by Nathan Goodyear on 23 Feb 11 - No Cached
  • Sufficient favorable clinical experience over the last 10 years suggests that PN is a relatively safe and effective method for reversing maternal malnutrition and promoting normal fetal growth and development.
  • Nathan Goodyear on 23 Feb 11
     
    IV nutritional therapy shown to be safe 
Nathan Goodyear

ScienceDirect - Obstetrics & Gynecology : Low whole blood glutathione levels in pregnan... - 0 views

www.sciencedirect.com/...S0029784498003330

glutathione PIH HELLP syndrome pregnancy pregnant GSH detoxification

shared by Nathan Goodyear on 02 Nov 11 - No Cached
  • Nathan Goodyear on 02 Nov 11
     
    glutathione low in pregnancies complicated by PIH and HELLP syndrome. Every woman should have her detoxification capacity evaluated prior to pregnancy.
Nathan Goodyear

American Journal of Obstetrics & Gynecology Home Page - 0 views

www.ajog.org/...fulltext

"Vaginal mesh" immune system

shared by Nathan Goodyear on 31 Aug 18 - No Cached
  • M1 macrophages are characterized by the secretion of reactive oxygen species and proinflammatory cytokines and chemokines and can be identified via the cell surface marker CD86
  • M2 macrophages secrete growth factors and antiinflammatory immune modulators and can be identified by the cell surface marker CD206
  • an overzealous M2 response can also lead to excess tissue deposition and fibrosis
  • ...14 more annotations...
  • Studies of similar meshes that are used in hernia repair have demonstrated that all polypropylene meshes induce a prolonged inflammatory response at the site of implantation
  • the long-term presence of activated inflammatory cells, such as macrophages at the mesh tissue interface, can impact negatively the ability of the mesh to function as intended.
  • All M1 proinflammatory and M2 proremodeling cytokines and chemokines were increased in mesh explants as compared with nonmesh tissue (Table 3Table 3), which indicated a robust, active, and ongoing host response to polypropylene long after implantation
  • Comparison of the ratio of the M2 proremodeling cytokines (IL-10+IL-4) with the M1 proinflammatory cytokines (TNF-α+IL-12p70) revealed a decrease in mesh explants as compared with controls (P = .003), which indicated a shift towards a proinflammatory profile.
  • Mesh explants contained a higher number of total cells/×200 field when compared with controls (682.46 ± 142.61 cells vs 441.63 ± 126.13 cells; P < .001) and a lower ratio of M2:M1 macrophages (0.260 ± 0.161 cells vs 1.772 ± 1.919; P = .001), which supported an ongoing proinflammatory response.
  • the host response was proportional to the amount of material in contact with the host
  • A persistent foreign body response was observed in mesh-tissue complexes that were excised from women who required surgical excision of mesh months to years after mesh implantation
  • The host response was characterized by a predominance of macrophages with an increase in both proinflammatory and proremodeling cytokines/chemokines along with increased tissue degradation, as evidenced by increased MMP-2 and -9
  • Mesh-tissue complexes removed for mesh exposure had increased pro–MMP-9 that indicated a proinflammatory and tissue destruction–type response
  • The presence of macrophages, elevated cytokines, chemokines, and MMPs in tissue-mesh complexes that were excised from patients with exposure or pain suggests that polypropylene mesh elicits an ongoing host inflammatory response
  • In the presence of a permanent foreign body, the implant is surrounded with a fibrotic capsule because it cannot be degraded
  • For hernia meshes, if the fibers are too close (<1 mm), the fibrotic response to neighboring fibers overlaps, or “bridges,” and results in “bridging fibrosis” or encapsulation of the mesh
  • Gynemesh PS has a highly unstable geometry when loaded that resulted in pore collapse and increasing stiffness of the product
  • mesh shrinkage (50-70%) has been described to occur after transvaginal insertion of prolapse meshes
  • Nathan Goodyear on 31 Aug 18
     
    Mesh and the abnormal immune response.
Nathan Goodyear

Survival implications of time to surgical treatment of endometrial cancers - American J... - 0 views

www.ajog.org/...fulltext

uterine cancer endometrial cancer surgery

shared by Nathan Goodyear on 05 Sep 19 - No Cached
  • Nathan Goodyear on 05 Sep 19
     
    Study finds that early (defined as 1-2 weeks after diagnosis) surgery after diagnosis of uterine cancer is associated with increased complications including death. This compared to lower postoperative death rates in delay out to 3-4 weeks.
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