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Dr Jennifer Martinick shares the hair loss experiences of Young Men's.

Don't forget about progesterone when it comes to men's health

nice and short review on testosterone and men's  health.

Benefits and risks of testosterone therapy discussed.  This study gives a brief history of hypogonadism,  highlights the different therapeutic techniques.  Most important, is the evidence based positive effects and side effects. The majority of the side effects occurs through overdosing and the physiologic dysfunction that occurs in these men's micronenvironments.

Pharma Sust 250mg injections treat hypogonadism disorders in men, after the illness, impotence due to lack of hormones, menstrual symptoms in men such as reducing sexual pleasure and physiological activities. Side effects: The drug can cause erectile dysfunction, signs of excessive sexual stimulation, reduced sperm count, decreased volume of ejaculation, water & salt retention. In pre-puberty boys: develop sex early, increase the frequency of erectile dysfunction, enlargement of the penis, and early growth of bone heads.

Hyperspermia & Hypospermia are two conditions that are lesser-known but may impact quantity of men's sperm and hence ability to conceive a child. Both conditions have different symptoms, causes, & treatments but share the same outcome, i.e., fertility complications.

review study points out that exercise, predominantly cardio, improved ED in men.

Metabolic syndrome in men associated with progressive BPH and increased severity of LUTS.

optimal weight associated with higher testicular volume and Testosterone levels in men.  Maternal smoking and higher cord bleed estrogens associated with lower sperm output.  This would with the other literature on EDCs.

Granted, these are in men seen in an infertility clinic, but Bisphenol A (BPA) found to disrupt thyroid, increase the E2:T ratio, and a decrease in the free androgen index.  Interestingly, 89% of the men seen in this study tested positive for BPA in the urine.

commonly used pesticides are found to be anti-androgens.  This is growing problem in men today. 

Nice review of all the sex hormones and their relationship to CVD in men.  

This study found that lower TT and E1 associated with more "poor health" as defined by questionnaire.  The conclusion might lead one to think that Estrogen therapy is need in men.  Eightly percent of estrogen production in men occurs from Testosterone.  If Testosterone declines, then estrogen production will likewise decline.  A simple fact that the authors did not comment on.  Also, E1 binds with high affinity to ER alpha, which is pro-inflammatory and pro-proliferative: neither of which is a positive health benefit.   This appears to point more to a broad HPA suppression as an association to the "poor health".

Again, Testosterone and here Estradiol are merely there for libido and sex.  What tunnel vision?!  What about hsCRP?  What about fibrinogen?  What about IL-1beta?  What about TNF-alpha?  These inflammatory cytokines have all been reported to elevate as a result of estrogen production in men.   And PSA?  No mention of it here.   This linear, tunnel vision thinking on hormones has got to stop! The study points out that all clients were using AIs and SERMs irregardless of whether they had elevated estrogens or not.  That is not a well designed study.  One group should have had AI's if elevated estrogens were present and another group should not--this would compare the effects of aromatase activity.  Second, this was simply a retrospective chart review.  Third, a 50% conversion of 34,000 + men is very high when you look at the literature.  Fourth, they point to gynecomastia as a means of negative?  The cardiovascular implications are more significant.  These studies just seem to focus on superficial things.  Fifth, did libido problems exist before?  What were the free levels?   This falls in the paucity of data (2 studies) that point to excessive lowering of estradiol effecting libido and sexual performance.

So this is what passes as science these days.  The study looked at whether pre-therapy Testosterone evaluation was beneficial in men prescribed Testosterone therapy.  What?!

Increased risk of atrial fibrillation in men exercising more than 5 days per week.  The study looked at men 45-79.  In contrast, walking and bicycling later in life was associated with decreased risk.

Saliva Testing of Testosterone is standard

Declining Testosterone, calculated free Testosterone, Estradiol, and Estrone levels appear to be associated with muscle mass/strength decline in elderly men.  This points to a global decrease in HPA function rather than an individual, specific hormone deficiency.

Abstract published ahead of print finds that DHT and calculated free DHT was associated with CVD and all-cause mortality.  This cohort found that Total Testosterone and calculated free Testosterone were not.  

Study finds that men with opiated induced low T have improvement in pain with Testosterone therapy.  Opiates are one of the many causes of low Testosterone (see my book Man Boob Nation).  Low T has been associated with increase inflammation in men.  Thus a normalization of Testosterone would provide anti-inflammatory effects.