Skip to main content

Home/ Dr. Goodyear/ Group items tagged DihydroTestosterone

Rss Feed Group items tagged

Nathan Goodyear

Dihydrotestosterone treatment in men with coronary artery disease. II. Influence on myo... - 0 views

  •  
    dihydrotestosterone shown to improve cardiac function measures.
Nathan Goodyear

Stable Intraprostatic Dihydrotestosterone in Healthy Medically Castrate Men Treated wit... - 0 views

  •  
    Study finds that intraprostatic DHT levels correlate to Testosterone in TRT.  
Nathan Goodyear

Neutral associations of testosterone, dihydrotestosterone and estradiol with fatal and ... - 0 views

  •  
    study of middle aged men (mean age--50) finds no correlation between Testosterone, DHT, and higher Estradiol levels in CVD outcomes, including mortality.  Men who died during the study had lower total Testosterone, free Testosterone, and DHT levels than those that survived during the study.
Nathan Goodyear

Elevated Dihydrotestosterone is Associated with Testosterone-Induced Erythrocytosis - 0 views

  •  
    study proposes evaluation DHT levels in men with erythrocytosis on Testosterone therapy.
Nathan Goodyear

Serum Androgen Bioactivity During 5{alpha}-Dihydrotestosterone Treatment in Elderly Men... - 0 views

  •  
    transdermal DHT shown to increase DHT levels and shown to increase  androgenic effects in elderly men.
Nathan Goodyear

Dihydrotestosterone Treatment in Adolescents with Delayed Puberty: Does it Explain Insu... - 0 views

  •  
    DHT found to have no effect insulin and insulin resistance in young men.
Nathan Goodyear

Dihydrotestosterone: a rati... [Baillieres Clin Endocrinol Metab. 1998] - PubMed - NCBI - 0 views

  •  
    DHT as a Testosterone alternative
Nathan Goodyear

Comparative pharmacokinetics of three d - PubMed Mobile - 0 views

  •  
    Dihydrotestosterone shown to be a good alternative to Testosterone for male androgen replacement.
Nathan Goodyear

Asian Journal of Andrology - A role for dihydrotestosterone treatment in older men? - 0 views

  •  
    This study shows that DHT is a good alternative androgen to Testosterone.  It was shown to have no positive/negative effect on the prostate.  The negative of this study was found to be bone loss from supra physiologic DHT.  The point there is to keep hormone replacement physiologic, as one should with all BHRT.
Nathan Goodyear

Dihydrotestosterone administration does - PubMed Mobile - 0 views

  •  
    high dose DHT found to have no negative prostate effect.  DHT replacement, in this study, was not found to raise the intraprostate DHT levels.
Nathan Goodyear

Long-term effects of dihydrotestosteron - PubMed Mobile - 0 views

  •  
    Study finds no effects on prostate from DHT.  
Nathan Goodyear

The Androgen Derivative 5α-Androstane-3β,17β-Diol Inhibits Prostate Cancer Ce... - 0 views

  • In the early stages, prostate cancer growth is dependent on circulating androgens
    • Nathan Goodyear
       
      This is in contrast to studies that show poor prognosis with Lower T at time of diagnosis of prostate cancer
  • 5α-reductase not only provides a potent amplification of the androgenic signal ( 4– 6), but it also prevents estrogen formation by subtracting testosterone from the action of aromatase ( 7, 8), thus blocking activation of the estrogen receptor subtypes (ERα and ERβ; refs. 9, 10)
  • ERβ is the prevailing subtype ( 11), and a growing body of evidence points to the protective role of this receptor in prostate cancer
  • ...3 more annotations...
  • It has been shown that the transformation of the dihydrotestosterone to 5α-androstane-3α,17β-diol (3α-diol) and 5α-androstane-3β,17β-diol (3β-Adiol), generates two metabolites unable to bind the androgen receptor, but possessing a very high affinity for the estrogen receptors
  • the effects of testosterone may result from the balance between the androgenic and the estrogenic molecules originating from its catabolism.
  • Recent data have been published postulating a direct estrogenic role of the 3β-hydroxylated derivatives of dihydrotestosterone in the prostate development and homeostasis
  •  
    Here is the full article.
Nathan Goodyear

Annals of Internal Medicine | Long-Term Effects of Dihydrotestosterone Treatment on Pro... - 0 views

  •  
    DHT at 70 mg daily shown to have no adverse effects in the prostate of "healthy" men older than 50.  However, it did increase DHT metabolites (3 alpha androstane-diol and 3 beta androstane-diol), decreased LH, Testosterone, Estradiol, FSH, increased hemoglobin, creatinine, lean mass and decreased fat.
Nathan Goodyear

In Older Men an Optimal Plasma Testosterone Is Associated With Reduced All-Cause Mortal... - 0 views

  •  
    Older men, 70-89, Testosterone in the middle range of normal and higher DHT was associated with the lowest death rates.  Estradiol was not found to be associated.  This study only looked at Total levels, free bioavailable levels were not assessed.  This study also highlights the basic thought, that more is not always better as it pertains to Testosterone.  It also highlights the importance of DHT.  Testosterone is a pro hormone.
Nathan Goodyear

In Older Men an Optimal Plasma Testosterone Is Associated With Reduced All-Cause Mortal... - 0 views

  •  
    Australian study of older men, 70-89, found that normal Testosterone and DHT levels were associated with lower death rates.  This is important as this is the first study to find the positive health benefit of DHT as well as Testosterone.  
Nathan Goodyear

Testosterone, Dihydrotestosterone and Incident Cardiovascular Disease and Mortality in ... - 0 views

  •  
    Abstract published ahead of print finds that DHT and calculated free DHT was associated with CVD and all-cause mortality.  This cohort found that Total Testosterone and calculated free Testosterone were not.  
Nathan Goodyear

Pattern recognition of estradiol, testosterone and dihydrotestosterone in children's sa... - 0 views

  •  
    Sochastic sensors and pattern recognition proposed to improve levels of Estradiol, Testosterone, and DHT in salivary sampling in young children.  These levels are very low in pre-pubertal children and makes detection by ELIZA difficult.  This proposed mechanism improves hormone detection.
Nathan Goodyear

Higher serum testosterone and dihydrotestosterone, but not estradio... - PubMed - NCBI - 0 views

  •  
    Higher Testosterone and DHT levels in men was found to be positively associated with FEV1 and FVC; Estradiol was not.  The question here is cause or effect.   Also interesting is the fact that smokers had higher Testosterone levels compared to non-smokers.
Nathan Goodyear

In Older Men an Optimal Plasma Testosterone Is Associated With Reduced All-Cause Mortal... - 0 views

  •  
    men with Testosterone levels in the middle quintiles had the lowest risk of death compared to low and high quintile levels.  
Nathan Goodyear

Dihydrotestosterone is a peripheral paracrine hormone. - PubMed - NCBI - 0 views

  •  
    DHT is a paracrine hormone.  The most bioactive metabolite is 3-alpha-androstanediol.
1 - 20 of 50 Next › Last »
Showing 20 items per page