Group items tagged aromatase inhibition - Dr. Goodyear

Red Versus White Wine as a Nutriti... [J Womens Health (Larchmt). 2011] - PubMed - NCBI - 0 views

www.ncbi.nlm.nih.gov/...22150098

wine red white aromatase inhibition premenopausal women breast cancer

shared by Nathan Goodyear on 06 Feb 12 - No Cached

Nathan Goodyear on 06 Feb 12

red wine does appear to have health benefits over white wine through aromatase inhibition. Aromatase inhibition reduces estrogen levels. So, if the breast cancer risk is associated with elevated estrogen, then this would logically reduce the risk. The exact amount is unknown, but aromatase inhibition is a treatment of those with breast CA.

<div class="cArrow"> </div><div class="cContentInner">red wine does appear to have health benefits over white wine through aromatase inhibition. Aromatase inhibition reduces estrogen levels. So, if the breast cancer risk is associated with elevated estrogen, then this would logically reduce the risk. The exact amount is unknown, but aromatase inhibition is a treatment of those with breast CA.</div>

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Aromatase and regulation of the estrogen-to... [Ann N Y Acad Sci. 2014] - PubMed - NCBI - 0 views

www.ncbi.nlm.nih.gov/...24684533

aromatase aromatase activity vitamin D estrone E1 inflammation RA rheumatoid arthritis

shared by Nathan Goodyear on 07 Apr 14 - No Cached

Nathan Goodyear on 07 Apr 14

Study looked at inflammatory markers in RA. The authors point to high aromatase activity, low androgens, and elevated estrone in synovial fluid as an indicator of a link between aromatase activity and inflammation production through E1 production. The authors also point to the 16 alpha metabolite pathway as pro-inflammatory as well. One very interesting point made by the authors is that vitamin D down regulates aromatase activity. In addition to NK-kappaB inhibition, this may be another mechanism by which vitamin D reduces inflammation.

<div class="cArrow"> </div><div class="cContentInner">Study looked at inflammatory markers in RA. The authors point to high aromatase activity, low androgens, and elevated estrone in synovial fluid as an indicator of a link between aromatase activity and inflammation production through E1 production. The authors also point to the 16 alpha metabolite pathway as pro-inflammatory as well. One very interesting point made by the authors is that vitamin D down regulates aromatase activity. In addition to NK-kappaB inhibition, this may be another mechanism by which vitamin D reduces inflammation.</div>

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Aromatase inhibitors for male infertility. [J Urol. 2002] - PubMed - NCBI - 0 views

www.ncbi.nlm.nih.gov/...11792932

male infertility anastrozole arimidex aromatase inhibitor inhibition Testosterone:estradiol

shared by Nathan Goodyear on 26 Feb 12 - No Cached

Nathan Goodyear on 26 Feb 12

aromatase inhibitor, arimidex (anastrozole), shown to be effective therapy in male infertility in those with high aromatase activity. The effect was seen through improved Testosterone:Estradiol ratio through aromatase inhibition.

<div class="cArrow"> </div><div class="cContentInner">aromatase inhibitor, arimidex (anastrozole), shown to be effective therapy in male infertility in those with high aromatase activity. The effect was seen through improved Testosterone:Estradiol ratio through aromatase inhibition.</div>

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Effects of aromatase inhibition vs. testosterone in older men with low testosterone: ra... - 0 views

www.ncbi.nlm.nih.gov/...26588809

low T low Testosterone Testosterone testosterone therapy aromatase inhibitors aromatase inhibition aromatase inhibitor aromatase men male hormones strength muscle mass muscle bone mineral density

shared by Nathan Goodyear on 07 Dec 15 - No Cached

Nathan Goodyear on 07 Dec 15

No surprise that Testosterone therapy improves Testosterone levels in men with low T, but aromatase inhibition (AI) did as well. In this study, only lean mass increased compared to Testosterone therapy and placebo. Strength increased in both Testosterone and AI.

<div class="cArrow"> </div><div class="cContentInner">No surprise that Testosterone therapy improves Testosterone levels in men with low T, but aromatase inhibition (AI) did as well. In this study, only lean mass increased compared to Testosterone therapy and placebo. Strength increased in both Testosterone and AI.</div>

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Coadministration of anastrozole sustains therapeut... [J Sex Med. 2014] - PubMed - NCBI - 0 views

www.ncbi.nlm.nih.gov/...24119010

Testosterone aromatase aromatase activity estradiol anastrazole aromatase inhibitor aromatase inhibitors aromatase inhibition men male hormone hormones

shared by Nathan Goodyear on 19 Feb 14 - No Cached

Nathan Goodyear on 19 Feb 14

First, Testosterone pellets are not the way to go. Historically, these will go the way of all the implantable contraceptive devices. However, the conclusion of this study is good and confirms the benefit of anastrazole to inhibit aromatase activity and help to maintain Testosterone levels.

<div class="cArrow"> </div><div class="cContentInner">First, Testosterone pellets are not the way to go. Historically, these will go the way of all the implantable contraceptive devices. However, the conclusion of this study is good and confirms the benefit of anastrazole to inhibit aromatase activity and help to maintain Testosterone levels.</div>

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Effects of Transdermal Testosterone Gel or an Aromatase Inhibitor on Prostate Volume in... - 0 views

www.ncbi.nlm.nih.gov/...26950683

low T low Testosterone Testosterone prostate men male hormones PSA LUTS aromatase aromatase inhibition

shared by Nathan Goodyear on 08 Mar 16 - No Cached

Nathan Goodyear on 08 Mar 16

study finds both Testosterone therapy and aromatase inhibition in men > 65 both increase Testosterone levels. Increase in prostate size was only seen in the Testosterone only group; not in the AI group. This implicates aromatase activity in the increase in prostate volume.

<div class="cArrow"> </div><div class="cContentInner">study finds both Testosterone therapy and aromatase inhibition in men > 65 both increase Testosterone levels. Increase in prostate size was only seen in the Testosterone only group; not in the AI group. This implicates aromatase activity in the increase in prostate volume. </div>

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ScienceDirect - The Journal of Urology : AROMATASE INHIBITORS FOR MALE INFERTILITY - 0 views

www.sciencedirect.com/...S0022534701690992

AROMATASE INHIBITORS MALE INFERTILITY Testosterone Estradiol hormone hormonal imbalance

shared by Nathan Goodyear on 10 Oct 11 - No Cached

Nathan Goodyear on 10 Oct 11

aromatase inhibition in men to increase Testosterone:Estradiol ratio. Men with infertility have a low Testosterone:Estradiol ratio. Aromatase inhibitors inhibit Testosterone to Estradiol conversion

<div class="cArrow"> </div><div class="cContentInner">aromatase inhibition in men to increase Testosterone:Estradiol ratio. Men with infertility have a low Testosterone:Estradiol ratio. Aromatase inhibitors inhibit Testosterone to Estradiol conversion</div>

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Hops (Humulus lupulus) inhibits Oxidative Estrogen Metabolism and Estrogen-Induced Mali... - 0 views

www.ncbi.nlm.nih.gov/...PMC3252489

Hops estrogen aromatase inhibition aromatase inhibitor aromatase inhibitors aromatase hormone hormones

shared by Nathan Goodyear on 20 May 14 - No Cached

Nathan Goodyear on 20 May 14

Hops inhibits aromatase activity.

<div class="cArrow"> </div><div class="cContentInner">Hops inhibits aromatase activity.</div>

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Aromatase inhibitors in men: effects and therapeutic options - 0 views

www.ncbi.nlm.nih.gov/...PMC3143915

arimidex anastrozole aromatase inhibition inhibitor low T testosterone Testosterone:estradiol

shared by Nathan Goodyear on 26 Feb 12 - No Cached

Nathan Goodyear on 26 Feb 12

Aromatase inhibition using arimidex, anastrozole, shown to be an effective therapy to raise testosterone levels in men with low T and high aromatase activity.

<div class="cArrow"> </div><div class="cContentInner">Aromatase inhibition using arimidex, anastrozole, shown to be an effective therapy to raise testosterone levels in men with low T and high aromatase activity.</div>

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Effects of Aromatase Inhibition in Elderly Men with Low or Borderline-Low Serum Testost... - 0 views

jcem.endojournals.org/...1174.full

aromatase inhibitor Testosterone estradiol estrogen men male hormon hormoens psa

shared by Nathan Goodyear on 23 Sep 13 - No Cached

Nathan Goodyear on 23 Sep 13

Study looked at aromatase activity in androgen production in older men. The study found that aromatase inhibition with arimidex increased Testosterone production. PSA was also monitored and PSA increased in the smaller dose group versus the high dose group.

<div class="cArrow"> </div><div class="cContentInner">Study looked at aromatase activity in androgen production in older men. The study found that aromatase inhibition with arimidex increased Testosterone production. PSA was also monitored and PSA increased in the smaller dose group versus the high dose group.</div>

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Use of Aromatase Inhibitors in Large... [J Clin Endocrinol Metab. 2014] - PubMed - NCBI - 0 views

www.ncbi.nlm.nih.gov/...25226294

aromatase aromatase inhibition aromatase inhibitor Man Boobs gynecomastia male hormones

shared by Nathan Goodyear on 17 Sep 14 - No Cached

Nathan Goodyear on 17 Sep 14

aromatase inhibition therapy shown to reduce and/or eliminate man boobs in young boys with sertoli cell tumors.

<div class="cArrow"> </div><div class="cContentInner">aromatase inhibition therapy shown to reduce and/or eliminate man boobs in young boys with sertoli cell tumors.</div>

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Endogenous Estrogens Influence Endothelial Function in Young Men - 0 views

circres.ahajournals.org/...1127.long

aromatase inhibition anastrozole arimidex men

shared by Nathan Goodyear on 25 Apr 12 - No Cached

Nathan Goodyear on 25 Apr 12

aromatase inhibition with anastrozole, in this study, resulted in impaired flow mediated dilation. No resultant change in inflammatory markers were seen. Again, my problem with this study is the use of serum for the hormone evaluation. I would bet not enough aromatase inhibition was provided.

<div class="cArrow"> </div><div class="cContentInner">aromatase inhibition with anastrozole, in this study, resulted in impaired flow mediated dilation. No resultant change in inflammatory markers were seen. Again, my problem with this study is the use of serum for the hormone evaluation. I would bet not enough aromatase inhibition was provided.</div>

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Inhibition of aromatase activity by flavonoids. [Arch Pharm Res. 1999] - PubMed result - 0 views

www.ncbi.nlm.nih.gov/...10403137

aromatase inhibition flavonoids chrysin

shared by Nathan Goodyear on 01 Mar 11 - No Cached

Over 50% of the flavonoids significantly inhibited aromatase activity, with greatest activity being demonstrated with apigenin (IC50: 0.9 microg/mL), chrysin (IC50: 1.1 microg/mL), and hesperetin (IC50: 1.0 microg/mL)
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Nathan Goodyear on 01 Mar 11

flavonoids inhibit aromatase activity

<div class="cArrow"> </div><div class="cContentInner">flavonoids inhibit aromatase activity</div>

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Cognitive dysfunction in postmenopausal breast cancer patients on aromatase inhibitors,... - 0 views

informahealthcare.com/...era.11.112

breast cancer cognitive decline dysfunction women estradiol aromatase

shared by Nathan Goodyear on 10 Mar 14 - No Cached

Nathan Goodyear on 10 Mar 14

Just the abstract here. Declining estradiol production found to be associated with increased cognitive dysfunction or cognitive decline in those using aromatase inhibitor therapy. Aromatase inhibition therapy is used to block Testosterone to Estradiol production in women with ER+ breast cancer.

<div class="cArrow"> </div><div class="cContentInner">Just the abstract here. Declining estradiol production found to be associated with increased cognitive dysfunction or cognitive decline in those using aromatase inhibitor therapy. Aromatase inhibition therapy is used to block Testosterone to Estradiol production in women with ER+ breast cancer.</div>

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Melatonin inhibits aromatase promoter expression by regulating cyclooxygenases expressi... - 0 views

www.ncbi.nlm.nih.gov/...PMC2778514

cyclooxygenase aromatase inhibition cancer COX2 aromatase melatonin aromatase inhibitor

shared by Nathan Goodyear on 17 Nov 21 - No Cached

Nathan Goodyear on 17 Nov 21

Melatonin downregulates aromatase expression through COX2

<div class="cArrow"> </div><div class="cContentInner">Melatonin downregulates aromatase expression through COX2</div>

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Effect of hop (Humulus lupulus L.) flavono... [J Agric Food Chem. 2006] - PubMed - NCBI - 0 views

www.ncbi.nlm.nih.gov/...16608212

Hops aromatase inhibitor aromatase inhibition aromatase inhibitors estrogen men male hormone hormones aromatase Humulus Lupulus

shared by Nathan Goodyear on 20 May 14 - No Cached

Nathan Goodyear on 20 May 14

Hops is a natural aromatase inhibitor

<div class="cArrow"> </div><div class="cContentInner">Hops is a natural aromatase inhibitor</div>

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Modulation of Aromatase by Phytoestrogens - 0 views

www.hindawi.com/...594656

aromatase activity aromatase inhibition phytoestrogens aromatase inhibitor aromatase inhibitors aromatase

shared by Nathan Goodyear on 04 Apr 21 - No Cached

inhibition of estradiol synthesis attenuates renal injury in male streptozotocin-induce... - 0 views

ajprenal.physiology.org/...F634.full.pdf

testosterone hormone hormones kidney kidneys diabetes DM renal system aromatase

shared by Nathan Goodyear on 05 Mar 13 - No Cached

Nathan Goodyear on 05 Mar 13

Study finds that inhibition of aromatase activity in diabetic male rats provided renal protection. There has been debate about the effects of testosterone therapy on the renal system. However, I propose that aromatase activity and conversion to estrogen is the negative effects of Testosterone. Other than over dosing men. Though this is a rat study, this study does support the theory.

<div class="cArrow"> </div><div class="cContentInner">Study finds that inhibition of aromatase activity in diabetic male rats provided renal protection. There has been debate about the effects of testosterone therapy on the renal system. However, I propose that aromatase activity and conversion to estrogen is the negative effects of Testosterone. Other than over dosing men. Though this is a rat study, this study does support the theory.</div>

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https://www.researchgate.net/profile/Lai_Leung/publication/7167819_The_red_wine_polyphe... - 0 views

www.researchgate.net/...00b7d5280e17072407000000.pdf

bioflavonoids resveratrol aromatase inhibition aromatase inhibitor aromatase inhibitors hormones breast cancer cancer

shared by Nathan Goodyear on 04 Jan 16 - No Cached

Nathan Goodyear on 04 Jan 16

the bioflavonoid Resveratrol shown to inhibit Aromatase at the translation level and at the enzyme level in the analysis of breast cancer cells in culture.

<div class="cArrow"> </div><div class="cContentInner">the bioflavonoid Resveratrol shown to inhibit Aromatase at the translation level and at the enzyme level in the analysis of breast cancer cells in culture.</div>

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Progesterone Receptor Inhibits Aromatase and Inflammatory Response Pathways in Breast C... - 0 views

mend.endojournals.org/...1812.long

progesterone receptor receptors PR breast cancer anti-inflammatory

shared by Nathan Goodyear on 12 Nov 12 - No Cached

Nathan Goodyear on 12 Nov 12

Progesterone receptor (PR) shown to provide an important anti-inflammatory role in breast cancer in this study. PR shown to increase NF-kappaB inhibitor IkBalpha, shown to inhibit aromatase activity, shown to inhibit COX-2 expression and shown to inhibit HER-2/neu expression.

<div class="cArrow"> </div><div class="cContentInner">Progesterone receptor (PR) shown to provide an important anti-inflammatory role in breast cancer in this study. PR shown to increase NF-kappaB inhibitor IkBalpha, shown to inhibit aromatase activity, shown to inhibit COX-2 expression and shown to inhibit HER-2/neu expression.</div>

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