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Nathan Goodyear

Progesterone for Symptomatic Perimenopause Treatment - Progesterone politics, physiolog... - 0 views

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    Progesterone is the primary hormone issue in perimenopause for women.
Nathan Goodyear

Gonadal hormone levels and platelet tryptophan and serotonin concentrations in perimeno... - 0 views

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    Interesting: study finds no association between tryptophan and serotonin levels and depression.  The study found no difference between 44 "depressed" perimenopausal women and 19 "without depression".  Serotonin therapy of depression??  However, poor sleep and hot flashes did.
Nathan Goodyear

Sex Hormone-Binding Globulin and the Free Androgen Index Are Related to Cardiovascular ... - 0 views

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    The opposite effect strikes again: elevated free androgen index is associated with CV risk in perimenopause women across 5 ethnic groups.  Low SHBG was associated with increased CVD.
Nathan Goodyear

Salivary Testing of Reproductive Hormones - Virginia Henderson International Nursing Li... - 0 views

  • Study results demonstrate there is adequate evidence to support use of saliva testing as an effective clinical tool for measuring hormone status in perimenopausal and menopausal women
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    2007 review states: "there is adequate evidence to support use of saliva testing as an effective clinical tool for measuring hormone status in perimenopausal and menopausal women".  Pretty definitive statement.  This was a worldwide analysis
Nathan Goodyear

Association between hyperinsulinemia and endogeno... [Metabolism. 2002] - PubMed - NCBI - 0 views

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    Increasing androgen levels associated with perimenopause/menopause transition.  This is associated with increasing insulin resistance.
Nathan Goodyear

Healthcare | Free Full-Text | Association of Mid-Life Changes in Body Size, Body Compos... - 0 views

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    great review of the menopause transition and the effect of weight and hormones.  For example, muscle loss is found in menopause vs perimenopause.  Increased estrogen production occurs from non-ovary sites i.e. visceral and SQ fat.
Nathan Goodyear

The Journal of Nutritional Biochemistry - Record - 0 views

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    study shows that smoking cessation, physical inactivity, menopause, hysterectomy and energy intake associated with the perimenopause weight gain.  What is interesting about it is the energy imbalance is small that results in a big weight gain over time.  We need to look closely and be more frank with out clients about the risk that a hysterectomy poses for her health post surgery.
Nathan Goodyear

The effects of compounded bioident... [Int J Pharm Compd. 2013 Jan-Feb] - PubMed - NCBI - 1 views

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    3 year study finds improvement in classic menopausal symptoms for women in perimenopause and menopause with improvement in other parameters: fasting glucose, cholesterol, MMP-9, CRP, fibrinogen and other clotting factors.  This study used bioidentical Bi-est, progesterone, and in some DHEA and Testosterone.
Nathan Goodyear

Is Timing Everything? New Insights into Why the Effect of Estrogen Therapy on Memory Mi... - 0 views

  • Women who have an oophorectomy before the normal age at menopause show an increased risk for cognitive impairment or dementia later in life unless they are treated with estrogen until the normal age at menopause
  • SIRT1 has been implicated in the disruption of mitochondrial bioenergenetics in Alzheimer's disease and mild cognitive impairment
  • the increase in dementia observed with CEE/MPA rather than CEE alone suggests potential deleterious effects of MPA on brain function in older women
  • ...1 more annotation...
  • SIRT 1 as a potential mediator of the impact of E2
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    Early estrogen therapy in perimenopause and early menopause, with Estradiol, provides more health benefits than later therapy.  This article looked at Estrogen's effects on a woman's brain.  This likely has its origins in the change in estrogen receptors. The signal is not changing, but the reception of that signal is.  How else can one explain a different response to the same hormone dosage?
Nathan Goodyear

Sex Hormone-Binding Globulin and the Free Androgen Index Are Related to Cardiovascular ... - 0 views

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    A decrease in the SHBG in post menopause women is associated with increase in free Testosterone, which is associated with increase in MetS and CVD
Nathan Goodyear

CYP1A1 and CYP1B1 polymorphisms and their association with estradiol and estrogen metab... - 0 views

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    estrogen metabolites and associated risk.
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