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Nathan Goodyear

Delayed Neuroendocrine Sexual Maturation in Female Rats After a Very Low Dose of Bisphe... - 0 views

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    low dose of BPA in rat model finds delayed sexual maturation.
Nathan Goodyear

Induction at high incidence of ductal prostate adenocarcinomas in NBL/Cr and Sprague-Da... - 0 views

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    Adding Estradiol to Testosterone in rate model significantly increases prostate carcinogenesis in rat model.
Nathan Goodyear

Selenomethionine and α-Tocopherol Do Not Inhibit Prostate Carcinogenesis in t... - 0 views

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    In this animal study, estradiol is added to Testosterone to increase prostate carcinogenesis.  Previous rat studies have shown that adding estradiol to Testosterone, which occurs naturally, increases prostate cancer risk.  
Nathan Goodyear

Moderate exercise ameliorates dysregulated hippocampal glycometabolism and memory funct... - 0 views

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    moderate exercise improves the memory of rats in diabetes model.
Nathan Goodyear

Reproductive toxicologic evaluations of Bulbine natalensis Baker stem extract in albino... - 0 views

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    Bulbine natalensis Baker stem extract found to increase LH and Testosterone in wistar rats in 7 days at doses of 25 to 50 mg/kg; this effect was not found at 100 mg/kg.  The result was an increase in testes size, rate of mating, libido, and fertility.
Nathan Goodyear

High-fructose diet leads to visceral adiposity and hypothalamic leptin resistance in ma... - 0 views

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    high fructose diet for just 9 weeks, > 60% liquid fructose, in rat model found to increase visceral adiposity, triglycerides, and lead to leptin resistance.
Nathan Goodyear

Curcumin inhibits hepatic protein-tyrosine phosphatase 1B and prevents hypertriglycerid... - 0 views

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    curcumin found to reduce leptin resistance and insulin resistance in fructose-induced hypertriglyceridiemia in rat model.
Nathan Goodyear

Testosterone and estrogen have opposing actions on inflammation-induced plasma extravas... - 0 views

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    Granted, this is a rat study, but estradiol shown to increase joint inflammation and testosterone shown to decrease inflammation.
Nathan Goodyear

The role of androgens and estrogens in the pathogenes... [J Urol. 1988] - PubMed - NCBI - 0 views

  • Testosterone can block the effect of estradiol on prostatitis, however treatment with an anti-estrogen or an aromatase inhibitor to block estrogen action does not improve prostatitis in the rat
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    Estradiol and imbalanced Testosterone:Estradiol ratio contributes to prostatitis.  In this study, with rats, aromatase inhibitors did not improve prostatitis.
Nathan Goodyear

Effects of Smoking on Plasma Testosterone Level and Erectile Function in Rats - Park - ... - 0 views

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    smoking reduces serum testosterone in rats.  The real question is what does it do to the salivary levels (tissue) and the metabolism of testosterone.
Nathan Goodyear

Effects of progesterone administration on infarct volume and functional deficits follow... - 0 views

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    progesterone shown to provide substantial reduction in volume of infarct in rat stroke model.  This is very promising, and with with other studies revealing the same benefit in the human brain, progesterone should become a part of initial treatment in those with acute brain injuries and should be evaluated for those with aging diseases of the brain.
Nathan Goodyear

Abnormalities of leptin and ghrelin regulation in obesity-prone juvenile rats - 0 views

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    leptin sensitivity and not gherlin shown to play role in obesity in Diet induce obesity rat model
Nathan Goodyear

Caloric restriction increases adiponectin expression by adipose tissue and prevents the... - 0 views

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    Calorie restriction increases adiponectin secretion from adipocytes.  Another plus of calorie restriction.  Remember, adiponectin and insulin are inversely associated.  Granted, this is in a rat model, but still supporting the overall health benefits of calorie restriction.
Nathan Goodyear

Perinatal exposure to low-dose bisphenol A affects the neuroendocrine stress response i... - 0 views

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    intra uterine exposure to BPA disrupts stress response in rat model.
Nathan Goodyear

Aromatase activity in the rat brain: Hormonal regulation and sex differences - 0 views

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    Rat study finds balance of DHT and estradiol play important role.  The production of DHT removes Testosterone from the pool to make estradiol through aromatase activity.
Nathan Goodyear

Testosterone Induces Molecular Changes in Dopamine Signaling Pathway Molecules in the A... - 0 views

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    Testosterone modulates dopaminergic pathways in the the brain.  This was a rat model.  This points to some of the euphoria experienced by men on Testosterone likely occurs through dopamine.
Nathan Goodyear

Ameliorative Effect of Vitamin C on Serum Liver Enzymes in Lead-Induced Toxicity in Wis... - 0 views

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    vitamin C reduces liver toxicity with lead (Pb) exposure in Wistar rats.
Nathan Goodyear

Prophylactic and therapeutic effects of n-3 polyunsaturated fatty acids, capsaicin, and... - 0 views

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    Rat study, but it finds that n-3, capsaicin, and curcumin can not only decrease the inflammation associatied with arthritis, but it can delay it all together.
Nathan Goodyear

AmeliorativeEffect ofVitaminC on Serum Liver Enzymes in Lead-Induced Toxicity in Wistar... - 0 views

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    Study in Wistar Rats finds that IV vitamin C reduces the liver damage (manifested through elevated liver enzymes) associated with lead toxicity.
Nathan Goodyear

Resveratrol inhibits 11β-hydroxysteroid dehydrogenase type 1 activity in rat ... - 0 views

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    Resveratrol shown to inhibit 11beta-hydroxysteroid dehydrogenase I in rat study.
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