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Nathan Goodyear

Selenium and L-carnitine reduce oxidative stress in the heart of rat induced by 2.45-GH... - 0 views

www.ncbi.nlm.nih.gov/...21360060

carnitine selenium heart health cardiovascular disease

shared by Nathan Goodyear on 11 Apr 17 - No Cached
  • Nathan Goodyear on 11 Apr 17
     
    animal study finds high dose Carnitine plus selenium protects against oxidative stress of the heart.
Nathan Goodyear

Combination of vitamin C and rutin on neuropa... [Arch Pharm Res. 2002] - PubMed - NCBI - 0 views

www.ncbi.nlm.nih.gov/...12009033

vitamin C neuropathy peripheral neuropathy C vitamin

shared by Nathan Goodyear on 25 Jun 12 - No Cached
  • Nathan Goodyear on 25 Jun 12
     
    Vitamin C plus rutin, in combination, shown to reduce oxidative stress markers in sciatic nerve.  Vitamin C will be an aid in therapy to treat peripheral neuropathy.
Nathan Goodyear

Associations Between 25-Hydroxyvit... [J Womens Health (Larchmt). 2012] - PubMed - NCBI - 0 views

www.ncbi.nlm.nih.gov/pubmed

vitamin D vitamin D weight gain overweight obesity inflammation

shared by Nathan Goodyear on 21 Aug 12 - No Cached
  • Nathan Goodyear on 21 Aug 12
     
    Those with higher vitamin D levels are associated with lower weight gain postmenopausal. Now, this could be due to increased outside exercise and activity.  However, due the NF-KappaB inhibition and resultant inflammation, it makes since that vitamin D reduces weight gain.  Plus it improves Insulin function and helps to control blood glucose.
Nathan Goodyear

Caloric restriction increases adiponectin expression by adipose tissue and prevents the... - 0 views

www.jnutbio.com/...abstract

calorie restriction adiponectin insulin resistance adipocytes fat tissue cells overweight obesity

shared by Nathan Goodyear on 31 Jul 12 - No Cached
  • Nathan Goodyear on 31 Jul 12
     
    Calorie restriction increases adiponectin secretion from adipocytes.  Another plus of calorie restriction.  Remember, adiponectin and insulin are inversely associated.  Granted, this is in a rat model, but still supporting the overall health benefits of calorie restriction.
Nathan Goodyear

[Effect of intravenous im... [Zhejiang Da Xue Xue Bao Yi Xue Ban. 2008] - PubMed - NCBI - 0 views

www.ncbi.nlm.nih.gov/...18705014

IV vitamin C vitamin C autoimmune disease inflammation

shared by Nathan Goodyear on 28 Aug 13 - No Cached
  • Nathan Goodyear on 28 Aug 13
     
    IV vitamin C plus IVIG is more effective at reducing TNF alpha in autoimmune disease model known as experimental autoimmune myocarditis.
Nathan Goodyear

Menopausal Hormone Therapy and Risk of Colorectal Cancer - 0 views

cebp.aacrjournals.org/...196.full

progesterone progestin estrogen breast cancer hormone hormones

shared by Nathan Goodyear on 19 Nov 13 - No Cached
  • Nathan Goodyear on 19 Nov 13
     
    This study looked at relative risk, but estrogen plus progestin reduces the risk of colorectal cancer.  Progestin is a poor sythetic progesterone analogue.  One wonders what additional benefit progesterone may add as studies have shown with regards to breast cancer.
Nathan Goodyear

http://www.ldnresearchtrust.org/sites/default/files/LDN_Cancer.pdf - 0 views

www.ldnresearchtrust.org/...LDN_Cancer.pdf

cancer LDN low dose naltrexone naltrexone vitamin D vitamin D

shared by Nathan Goodyear on 01 Oct 14 - No Cached
  • Nathan Goodyear on 01 Oct 14
     
    low dose naltrexone plus vitamin D3 to treat cancer
Nathan Goodyear

Therapeutic potentials of combined use of DMSA wit... [Biometals. 2008] - PubMed - NCBI - 0 views

www.ncbi.nlm.nih.gov/...17287888

DMSA Pb lead vitamin C vitamin C

shared by Nathan Goodyear on 17 Sep 14 - No Cached
  • Nathan Goodyear on 17 Sep 14
     
    Study of mice finds DMSA with calcium plus vitamin C chelates/mobilized Pb.
Nathan Goodyear

Effects of calcium-vitamin D co-supplementation... [Diabetologia. 2014] - PubMed - NCBI - 0 views

www.ncbi.nlm.nih.gov/...25005333

vitamin D vitamin D calcium HDL LDL insulin resistance insulin sensitivity HgbA1c insulin Diabetes

shared by Nathan Goodyear on 15 Sep 14 - No Cached
  • Nathan Goodyear on 15 Sep 14
     
    vitamin D plus calcium in those with Diabetes and low vitamin D four to improve insulin resistance, HDL, LDL, beta cell function, and HgbA1c.  This was a short course study of 8 weeks.  Only abstract available.
Nathan Goodyear

Review of health risks of low testosterone and testosterone administration - 0 views

www.ncbi.nlm.nih.gov/...PMC4391003

low Testosterone low T Testosterone men male hormone hormones health

shared by Nathan Goodyear on 28 Apr 15 - No Cached
  • Hypogonadism may be defined either as serum concentration of T (either total T, bioavailable T or free T) or as low T plus symptoms of hypogonadism
  • The Baltimore Longitudinal Study on Aging reported the incidence of total serum T < 325 ng/dL to be 20% for men in their 60s, 30% for men in their 70s and 50% for men over 80
  • The Massachusetts Aging Male Study reported that 12.3% of men aged 40 to 70 had a total serum T of < 200 ng/dL with 3 or more symptoms of hypogonadism
  • ...19 more annotations...
  • The Boston Area Community Health Study reported that 5.6% of men aged 30 to 70 were hypogonadal, as defined by total serum T < 300 ng/dL; or, free serum T < 5 ng/dL plus 3 or more symptoms of hypogonadism
  • In a health screening project among 819 men in Taiwan, the prevalence of hypogonadism (total serum T < 300 ng/dL) ranged from 16.5% for men in their 40s, 23.0% for men in their 50s, 28.9% for men in their 60s, and 37.2% for men older than 70 years of age
  • The prevalence of hypogonadism among men in Taiwan is higher than the prevalence reported in the Massachusetts Male Aging Study
  • CAG repeat sequence, within the androgen receptor (AR). Rajender et al[12] reviewed over 30 studies on the AR trinucleotide repeat and infertility
  • suggestion that CAG repeat length may determine androgen responsiveness, this issue is not clearly settled
  • reported prevalence of low T in older men range from 5.6% to 50%
  • Those in the hypogonadal group (n = 4269) had direct health care costs, that exceeded the eugonadal group (n = 4269) by an average of $7100 over the course of the observation window
  • higher economic burden and presence of co-morbidities for hypogonadism
  • minor to moderate improvements in lean mass and muscle strength
  • increased bone mineral density
  • modest enhancement in sexual function
  • reduced adiposity
  • lessening of depressive symptoms
  • Meta-analyses of clinical TRT trials as of 2010 have identified three major adverse events resulting from TRT: (1) polycythemia; (2) an increase in prostate-related events; and (3) and a slight reduction in serum high-density lipoprotein (HDL) cholesterol
  • polycythemia (> 3.5-fold increase in risk
  • TRT produced a 40% prostate enlargement in older hypogonadal male Veterans over 12 mo
  • no published analysis has reported measurable increases in prostate cancer risk or Gleason score in men undergoing TRT, or in hypogonadal men with a history of prostate cancer undergoing TRT
  • the prostate which highly expresses the type II 5α-reductase enzyme. Inhibition of this enzyme via finasteride (a type II 5α-reductase inhibitor) or dutasteride (a dual type I and II 5α-reductase inhibitor) reduces circulating DHT 50%-75% and > 90%, respectively[47], and reduces prostate mass[48] and prostate cancer risk
  • Normally estradiol partially regulates testosterone levels, at the hypothalamus, blunting LH and FSH release from the pituitary. As a selective estrogen receptor modulator, CC interrupts this pathway, and consequently there is a greater stimulation for the production of testosterone in Leydig cells
    • Nathan Goodyear
      Nathan Goodyear on 28 Apr 15
       
      this would only apply if E1 and/or E2 levels were elevated, which the authors make no mention of.
  • Nathan Goodyear on 28 Apr 15
     
    to be read
Nathan Goodyear

The effect of testosterone and fenofibrate, administered alone or in combination, on ca... - 0 views

www.ncbi.nlm.nih.gov/...26031507

Testosterone hormones cardiovascular disease hsCRP insulin insulin resistance insulin sensitivity

shared by Nathan Goodyear on 04 Jun 15 - No Cached
  • Nathan Goodyear on 04 Jun 15
     
    This study looked at oral Testosterone plus fenofibrate (tricor).  That is not the purpose of this post.  This study found that oral Testosterone decanoate reduced hsCRP and improved insulin sensitivity.  One caveat--Testosterone should not be given orally due to increased risk of hepatocellular cancer.
Nathan Goodyear

DHA dietary supplementation enhances the effects of exercise on synaptic plasticity and... - 0 views

www.ncbi.nlm.nih.gov/...PMC3208643

DHA n-3 omega 3 omega-3 fish oil cognition memory hippocampus exercise neuroplasticity BDNF brain derived neurotrophic factor lipid peroxidation

shared by Nathan Goodyear on 01 Nov 13 - No Cached
  • Nathan Goodyear on 01 Nov 13
     
    DHA enriched diet plus exercis improved cognition through a increase in brain derived neurotrophic factor (BDNF).  The result was increased neuroplasticity.  Additionally, they were shown to reduce hippocampal lipid peroxidation.
Nathan Goodyear

l-Theanine and caffeine improve task switching but not intersensory attention or subjec... - 0 views

www.sciencedirect.com/...S0195666310000267

caffeine attention l-theanine

shared by Nathan Goodyear on 03 Nov 13 - No Cached
  • Nathan Goodyear on 03 Nov 13
     
    small dose of l-theanine plus caffeine improves attention in short term.
Nathan Goodyear

What dietary modification best improves insulin sensitivity and why? - Weickert - 2012 ... - 0 views

onlinelibrary.wiley.com/...full

high protein diet insulin resistance nutrition exercise

shared by Nathan Goodyear on 22 Oct 13 - No Cached
  • cereal-fibre intake, under isoenergetic conditions, improves whole-body IR in both short-term and more prolonged studies
  • Nathan Goodyear on 22 Oct 13
     
    Great review of macronutrients and insulin resistance.  Caloric reduction plus exercise still the best method to reduce insulin resistance.   Long-term high protein intake increases insulin resistance.
Nathan Goodyear

Primary Care Respiratory Journal - 0 views

www.thepcrj.org/...view_article.php

honey coffee cough pulmonary respiratory

shared by Nathan Goodyear on 23 Oct 13 - No Cached
  • Nathan Goodyear on 23 Oct 13
     
    Honey plus coffee found to be better in resolving post-infectious cough than prednisolone.  This study was a head to head study.  The honey consisted of 500 grams and the coffee was a instant coffee of 70 grams.  The dosing frequency was 3 x daily.  
Nathan Goodyear

Effect of 12 weeks of periodized resistance training upon total plasma adiponectin conc... - 0 views

www.ncbi.nlm.nih.gov/...26274372

resistance training exercise aerobic exercise adiponectin

shared by Nathan Goodyear on 18 Aug 15 - No Cached
  • Nathan Goodyear on 18 Aug 15
     
    balance: exercise is no different. Cardio plus resistance training increases adiponectin over resistance training alone.
Nathan Goodyear

Calcium and vitamin d supplementation decreases incidence of stress fractures in female... - 0 views

www.ncbi.nlm.nih.gov/...18433305

vitamin d stress fractures bones calcium

shared by Nathan Goodyear on 24 Aug 15 - No Cached
  • Nathan Goodyear on 24 Aug 15
     
    low dose vitamin D plus higher dose of calcium reduced stress fractures in female military recruits.
Nathan Goodyear

Echinaforce Hotdrink versus Oseltamivir in Influenza: A randomized, double-blind, doubl... - 0 views

www.currenttherapeuticres.com/...abstract

influenza flu elderberry echinacea echinacea purpura natural

shared by Nathan Goodyear on 02 Jul 15 - No Cached
  • Nathan Goodyear on 02 Jul 15
     
    new study finds Echinacea plus elderberry out performs Tamiflu in the treatment of early flu-like symptoms.  This study was fairly large for a head to head randomized study.  I love it when natural therapies out perform prescription meds.
Nathan Goodyear

Effects of thyroxine as compared with thyroxine pl... [N Engl J Med. 1999] - PubMed result - 0 views

www.ncbi.nlm.nih.gov/...9971866

T3 T4 hypothyroidism armour thyroid USP

shared by Nathan Goodyear on 19 Nov 10 - No Cached
  • n patients with hypothyroidism, partial substitution of triiodothyronine for thyroxine may improve mood and neuropsychological function;
  • Nathan Goodyear on 19 Nov 10
     
    Effects of thyroxine as compared with thyroxine plus triiodothyronine in patients with hypothyroidism.
Nathan Goodyear

Nonfasting Apolipoprotein B and Triglyceride Levels as a Useful Predictor of Coronary H... - 0 views

atvb.ahajournals.org/...1918.long

lipoproteins apo B apo A1 apolipoproteins Apolipoprotein B Apolipoprotien A1 cholesterol HDL cardiovascular disease risk heart disease

shared by Nathan Goodyear on 26 Aug 14 - No Cached
  • Nathan Goodyear on 26 Aug 14
     
    non fasting apo B plus HDL is predictive of cardiovascular disease risk. Apo a1 was not predictive.  
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