ketogenic diet found to not deplete muscle glycogen in endurance athletes. The metabolism of the endurance athletes can do this via the high fat oxidation--estimates of 80%.
Mouse model finds that Cordyceps increased the interval to exhaustive exercise induced oxidative stress. SOD, Cat, and GPx were increased in the low, intermediate, and high dose Cordyceps groups. Oxidative stress markers MDA and 8-OHdG were lower in all groups
Increased risk of atrial fibrillation in men exercising more than 5 days per week. The study looked at men 45-79. In contrast, walking and bicycling later in life was associated with decreased risk.
BDNF increased metabolic biomarkers, MAPK, in hippocampus. This has implications in the treatment of learning disorders. Exercise has consistently been shown to be the most significant mechanism to increase BDNF.
Great review of macronutrients and insulin resistance. Caloric reduction plus exercise still the best method to reduce insulin resistance. Long-term high protein intake increases insulin resistance.
Breast cancer survivors (BCS) exhibit decreased physical function and quality of life (QOL) following cancer treatments. Resistance training (RT) may elicit positive changes in physical and mental well-being. This study assessed 27 BCS, pre-and post-intervention (six months) on the following variables: muscular strength (via one repetition maximum (1RM) of chest press and leg extension), physical function (via the Continuous Scale-Physical Functional Performance test) and QOL (via the Short Form-36 survey). RT consisted of two days/week of ten exercises including two sets of 8-12 repetitions at 52%-69% of their 1RM. A repeated measures analysis of variance revealed BCS significantly (p < 0.05) increased upper (71 ± 22 to 89 ± 22 kg) and lower body (74 ± 18 to 93 ± 24 kg) strength, total physical function (65.5 ± 12.1 to 73.6 ± 12.2 units) and the subcomponents of physical function: upper body strength (63.5 ± 16.3 to 71.2 ± 16.8 units), lower body strength (58.5 ± 14.9 to 68.6 ± 16.3 units), balance and coordination (66.5 ± 12.2 to 74.6 ± 11.6 units), and endurance (67.2 ± 12.0 to 75.0 ± 11.6 units). No changes were observed over time for subjective measures of physical function and QOL. Results showed RT could be an effective means to improve objective physical function in BCS. Further research is needed to clarify the effects of RT on subjective physical function and QOL.
Natural progesterone, but not medroxyprogesterone acetate, enhances the beneficial effect of estrogen on exercise-induced myocardial ischemia in postmenopausal women