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Nathan Goodyear

Gut bacteria may decrease weight loss from bariatric surgery -- ScienceDaily - 0 views

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    Article not yet available.  Just maybe, the but and the population of the micro biome in the gut should be the place to start, along with nutrition and exercise, instead of bariatric surgery.  Functional medicine has been pushing the micro biome impact on metabolism for years. I gladly welcome traditional medicine to the forefront of learning.
Nathan Goodyear

PLOS ONE: The Gut Microbiota and Developmental Programming of the Testis in Mice - 0 views

  • The intra-testicular level of testosterone in GF mice was found to be significantly lower than in SPF and CBUT mice
  • This study establishes a novel role for the commensal gut microbiota in the regulation of testicular development and function
  • Absence of the normal microbiota influences the formation and the integrity of the BTB as well as the intra-testicular levels of testosterone and serum levels of LH and FSH.
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  • Nutritional, socioeconomic, lifestyle and environmental factors (among others) are involved in the regulation of normal spermatogenesis.
  • he gut microbiota is one such potential source of environmental factors/products that has developed an intimate symbiotic relationship with host's physiology.
  • Manipulation of the gut microbiotia through dietary modification, pre- and probiotics can therefore be beneficial for the host's reproductive health.
  • In the current study, colonizing GF mice with CBUT resulted in an increased sperm production, suggesting that bacterial products, e.g. of fermentation, directly or indirectly, can affect the testis.
  • the absence of gut microbiota influenced testosterone levels
  • A recent study demonstrated that dietary supplementation of the probiotics Lactobacillus reuteri increased and restored testosterone levels in aging mice
  • bacterial metabolites such as butyrate have been shown to increase the levels of LH [43] and FSH
  • This suggests that butyrate most likely regulates testosterone production at the testicular level by stimulation of gene expression in Leydig cells and with little or no effect at the pituitary- hypothalamic levels.
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    gut micro biome effects spermatogenesis, Testosterone production, and the brain-testicle-barrier.
Nathan Goodyear

Taylor & Francis Online :: The microbiome as a target for endocrine disruptors: Novel c... - 0 views

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    EDCs are proposed to disrupted gut micro biome and thus effect androgen production and autoimmune risk.
Nathan Goodyear

http://www.biomed.cas.cz/physiolres/pdf/prepress/932627.pdf - 0 views

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    good discussion of the effects of resistance training on Testosterone and cortisol in obese men.  The literature is more more clear on the effects of resistance training on healthy men, but the evidence in obese men is less clear--likely due to the disrupted metabolism.
Nathan Goodyear

The Placenta Harbors a Unique Microbiome | Science Translational Medicine - 0 views

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    Paradigm shift: placenta is not sterile environment but contains bacteria from mother.  This microbiome may play role in the initiation of the offsprings gut micro biome.
Nathan Goodyear

Simultaneous d... [J Chromatogr B Analyt Technol Biomed Life Sci. 2009] - PubMed - NCBI - 0 views

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    salivary testosterone and DHEA evaluation by LC-MS/MS validated and shown to be applicable in the diagnosis and therapy in those men with low testosterone and DHEA.
Nathan Goodyear

Biomedical Papers: The prevalence of non organ specific and thyroid autoimmunity in pat... - 0 views

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    high prevalence of thyroid antibodies, TPO, in women with PCOS.  This does not prove cause and effect, merely an association.  Both are inflammation driven.
Nathan Goodyear

NK cells and pre-eclampsia. [Reprod Biomed Online. 2008] - PubMed - NCBI - 0 views

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    NK cells and their role in pre-eclampsia
Nathan Goodyear

Analysis of Relations between serum levels of Epitestosterone, Estradiol, Testosterone,... - 0 views

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    Great confusion exists in the medical profession about Testosterone and PSA and the health of the prostate. The conversion of Estrogen, whether E2 or E1, and other variables are responsible for increases in PSA while on Testosterone therapy. This study points out that Estradiol in men stimulates cell line growth of prostate cancer. In contrast, Epitestosterone, an androgen metabolite, has antiandrogen, inhibits this estrogen activity. Epitestosterone exists in an inverse relationship to Estradiol and IGF-1.
Nathan Goodyear

BioMed Central | Full text | Low salivary testosterone levels in patients with breast c... - 0 views

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    saliva testing used in breast cancer study
Nathan Goodyear

Why pesticides could be a common cause of prostate... [Biomed Pharmacother. 2009] - Pub... - 0 views

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    Pesticides as endocrine disruptors and increasing incidence of prostate and breast Cancer
Nathan Goodyear

BioMed Central | Full text | Pesticide exposure and risk of Parkinson's disease: a fami... - 0 views

  • hese data corroborate positive associations of broadly defined pesticide exposure with PD in families, particularly for sporadic PD
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    pesticide and Parkinson's disease
Nathan Goodyear

Progesterone induces the growth and infiltrat... [Biomed Res Int. 2014] - PubMed - NCBI - 0 views

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    Progesterone shown to stimulate growth and migration of astrocytes in the brain.  The has both implications in cancer, such as in astrocytomas, but also in TBI.  The study also found that the Progesterone antagonist RU486 inhibited this effect.  A more thorough evaluation would have included the pregnane metabolites.
Nathan Goodyear

Beneficial effects of testosterone therapy on... [Biomed Res Int. 2014] - PubMed - NCBI - 0 views

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    Testosterone in men with CHF found to improve diastolic function and exercise distance versus placebo.  
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LeanBiome™ (Official) | Get Save UpTo $540 Today Only! - 0 views

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