Docosahexaenoic acid-enriched egg consumption induces accretion of arachidonic acid in erythrocytes of elderly patients.
Payet M, Esmail MH, Polichetti E, Le Brun G, Adjemout L, Donnarel G, Portugal H, Pieroni G.
Br J Nutr. 2004 May;91(5):789-96.
PMID: 15137931
doi:10.1079/BJN20041106
Comparison of the effects of linseed oil and different doses of fish oil on mononuclear cell function in healthy human subjects.
Wallace FA, Miles EA, Calder PC.
Br J Nutr. 2003 May;89(5):679-89.
PMID: 12720588
Our findings suggest that administration of n-3 FA (EPA and DHA) in doses of at least 1.5 g/day for a prolonged period of time to patients with advanced cancer is associated with an improvement in clinical, biological and QoL parameters.
N-3 fatty acids, cancer and cachexia: a systematic review of the literature.
Colomer R, Moreno-Nogueira JM, García-Luna PP, García-Peris P, García-de-Lorenzo A, Zarazaga A, Quecedo L, del Llano J, Usán L, Casimiro C.
Br J Nutr. 2007 May;97(5):823-31. Review.
PMID: 17408522
doi:10.1017/S000711450765795X
A seasonal variation of calcitropic hormones, bone turnover and bone mineral density in early and mid-puberty girls - a cross-sectional study.
Viljakainen HT, Palssa A, Kärkkäinen M, Jakobsen J, Cashman KD, Mølgaard C, Lamberg-Allardt C.
Br J Nutr. 2006 Jul;96(1):124-30.
PMID: 16870000
Seasonal variation in S-25-OHD and bone remodelling markers accompanied by negative correlation between S-25-OHD and S-iPTH was seen in this cross-sectional study of adolescent girls. In addition, the seasonal rhythm contributed 7.0-7.6 % difference in the BMD of lumbar vertebrae and left femur in early puberty girls. This variation should be avoided since it could hamper peak bone mass attainment.
Not enough vitamin D: health consequences for Canadians.
Schwalfenberg G.
Can Fam Physician. 2007 May;53(5):841-54. Review
PMID: 17872747
Conclusion
Low levels of VTD are considered a major public health problem in Canada, especially during the winter. Those with risk factors should be screened for low 25(OH)D levels and repletion therapy instituted if needed. Researchers have estimated that the oral dose of vitamin D3 to attain and maintain 25(OH)D levels >80 nmol/L is 2200 IU/d if baseline levels are 20 to 40 nmol/L, 1800 IU/d if levels are 40 to 60 nmol/L, and 1160 IU/d if levels are between 60 and 80 nmol/L.64
We need to ensure that patients have healthy blood levels of 25(OH)D to prevent levels of parathyroid hormone from rising and to maximize absorption of calcium, magnesium, and phosphate. Positive effects on bone are marginal at best unless patients consume at least 800 IU/d of VTD. The emerging and exciting role of the VTD receptor and the actions of VTD in maintaining health in other cell types have become more apparent during the last decade.
Now a new and controversial book by an American doctor suggests that taking even higher levels of the vitamin - 10 to 15 times the recommended amounts - can work wonders.
Dr James Dowd, who works at the Arthritis Institute of Michigan, has been prescribing vitamin D to people suffering from chronic disorders such as arthritis, back pain and headaches and the result, he claims, is a huge improvement in their symptoms.
In his book, The Vitamin D Cure, Dr Dowd describes a number of success stories using this approach. One of his patients, Barbara, for instance, was obese, and suffered from arthritis in one leg as well as high blood pressure.
As Dowd explains: "In the past I would have given her anti-inflammatory drugs, pain medication, a pill to lose weight and drug treatment for hypertension."
Vitamin D and autoimmune rheumatic diseases.
Cutolo M.
Rheumatology (Oxford). 2009 Mar;48(3):210-2. Epub 2008 Oct 17.
PMID: 18930963
doi:10.1093/rheumatology/ken394
Urine pH is an indicator of dietary acid-base load, fruit and vegetables and meat intakes: results from the European Prospective Investigation into Cancer and Nutrition (EPIC)-Norfolk population study.
Welch AA, Mulligan A, Bingham SA, Khaw KT.
Br J Nutr. 2008 Jun;99(6):1335-43. Epub 2007 Nov 28.
PMID: 18042305
In conclusion, a more alkaline diet, higher fruit and vegetable and lower meat intake were related to more alkaline urine with a magnitude similar to intervention studies. As urine pH relates to dietary acid-base load its use to monitor change in consumption of fruit and vegetables, in individuals, warrants further investigation.
Synbiotic effect of Lactobacillus helveticus M92 and prebiotics on the intestinal microflora and immune system of mice.
Frece J, Kos B, Svetec IK, Zgaga Z, Beganović J, Lebos A, Susković J.
J Dairy Res. 2009 Feb;76(1):98-104. Epub 2009 Jan 5.
PMID: 19121230
doi:10.1017/S0022029908003737
Impact of fish oil enriched total parenteral nutrition on DNA synthesis, cytokine release and receptor expression by lymphocytes in the postoperative period.
Schauder P, Röhn U, Schäfer G, Korff G, Schenk HD.
Br J Nutr. 2002 Jan;87 Suppl 1:S103-10.
PMID: 11895146
doi:10.1079/BJN2001463
The application of probiotics in cancer.
de Moreno de LeBlanc A, Matar C, Perdigón G.
Br J Nutr. 2007 Oct;98 Suppl 1:S105-10. Review.
PMID: 17922945
doi:10.1017/S0007114507839602
itamin D and autoimmunity: new aetiological and therapeutic considerations.
Arnson Y, Amital H, Shoenfeld Y.
Ann Rheum Dis. 2007 Sep;66(9):1137-42. Epub 2007 Jun 8. Review.
PMID: 17557889
doi:10.1136/ard.2007.069831
A randomised comparison of increase in serum 25-hydroxyvitamin D concentration after 4 weeks of daily oral intake of 10 microg cholecalciferol from multivitamin tablets or fish oil capsules in healthy young adults.
Holvik K, Madar AA, Meyer HE, Lofthus CM, Stene LC.
Br J Nutr. 2007 Sep;98(3):620-5. Epub 2007 Apr 24.
PMID: 17456248
We conclude that fish oil capsules and multivitamin tablets containing 10 microg cholecalciferol administered over a 4-week period produced a similar mean increase in s-25(OH)D concentration.
"New research from Queen Mary, University of London and Harvard Medical School has revealed precisely why taking fish oils can help with conditions like rheumatoid arthritis."
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