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Nathan Goodyear

http://www.biomed.cas.cz/physiolres/pdf/prepress/932627.pdf - 0 views

www.biomed.cas.cz/...932627.pdf

resistance training exercise resistance Testosterone cortisol men obese obesity hormone hormones

shared by Nathan Goodyear on 02 Sep 14 - No Cached
  • Nathan Goodyear on 02 Sep 14
     
    good discussion of the effects of resistance training on Testosterone and cortisol in obese men.  The literature is more more clear on the effects of resistance training on healthy men, but the evidence in obese men is less clear--likely due to the disrupted metabolism.
Nathan Goodyear

PPARγ and human metabolic disease - 0 views

www.ncbi.nlm.nih.gov/...PMC1386124

PPAR-gamma perioxisome proliferator-activated receptor disease PPAR

shared by Nathan Goodyear on 24 Jan 13 - No Cached
  • PPARα and PPARδ appear primarily to stimulate oxidative lipid metabolism
  • PPARγ is principally involved in the cellular assimilation of lipids via anabolic pathways
  • PPARs are members of the nuclear hormone receptor superfamily
  • ...7 more annotations...
  • Expression of PPARγ is highest in adipose tissue,
  • PPARγ also plays a key role in the entraining of adipose tissue lipid metabolism to nutritional state
  • Its expression is highest postprandially
  • its activation leads to upregulation of genes that mediate FA uptake and trapping
  • PPARγ may also promote futile cycling in adipocytes between triglyceride (TG) esterification and de-esterification
  • its high expression in macrophages, which are now known to infiltrate the dysfunctional adipose tissue of obese subjects
    • Nathan Goodyear
      Nathan Goodyear on 28 Aug 14
       
      PPAR gamma is associated with adipocyte differentiation and lipid storage.
  • Nathan Goodyear on 24 Jan 13
     
    review of PPAR gamma
  • Blu Electronic Cigarettes on 03 Sep 14
     
    very informative! Thanks for sharing!
Nathan Goodyear

Pattern recognition of estradiol, testosterone and dihydrotestosterone in children's sa... - 0 views

www.nature.com/...srep05579.html

hormone hormones Estradiol Testosterone DHT dihydrotestosterone saliva salivary testing

shared by Nathan Goodyear on 02 Sep 14 - No Cached
  • Nathan Goodyear on 02 Sep 14
     
    Sochastic sensors and pattern recognition proposed to improve levels of Estradiol, Testosterone, and DHT in salivary sampling in young children.  These levels are very low in pre-pubertal children and makes detection by ELIZA difficult.  This proposed mechanism improves hormone detection.
Nathan Goodyear

Methadone induces testosterone suppression in patients with opioid addiction : Scientif... - 0 views

www.nature.com/...srep06189.html

Testosterone methadone opiates low T low Testosterone men male hormone hormones women female

shared by Nathan Goodyear on 02 Sep 14 - No Cached
  • Nathan Goodyear on 02 Sep 14
     
    Methadone use in men is associated with significant reduction in serum Total Testosterone levels in men.  In women, just the opposite is true, though this did not reach statistical significance.  The higher the dose of methadone in men, the lower the Testosterone.  The link between opiates and low T in men is very strong.  This is the first that I am aware of that points to the opposite effect in women.
Nathan Goodyear

Prevention and management of type 2 diabetes: dietary components and nutritional strate... - 0 views

www.thelancet.com/...fulltext

diabetes nutrition diet

shared by Nathan Goodyear on 02 Sep 14 - No Cached
  • Nathan Goodyear on 02 Sep 14
     
    Unfortunately, on the summary is available to public, but review of nutrition for Diabetes points to Mediterranean diet, high vegetable intake, olive oil, and non-red meat intake for protein--particularily beans and legumes.  Compare this to the average counseling for those with Diabetes today.  
Nathan Goodyear

Aromatase P450 Gene Expression in Human Adipose Tissue. ROLE OF A Jak/STAT PATHWAY IN R... - 0 views

www.jbc.org/...16449.full

aromatase aromatase activity hormone hormones

shared by Nathan Goodyear on 29 Aug 14 - No Cached
  • Nathan Goodyear on 29 Aug 14
     
    aromatase activity regulation in men and women.
Nathan Goodyear

Ovarian insufficiency and early pregnancy loss induced by activation of the innate immu... - 0 views

www.ncbi.nlm.nih.gov/...PMC437968

pregnancy loss TNF-alpha inflammation progesterone immune system

shared by Nathan Goodyear on 29 Aug 14 - No Cached
  • Nathan Goodyear on 29 Aug 14
     
    low Progesterone as a result of luteal phase defects results in an increase in TNF-alpha production.  The result is impaired fertility and increased first trimester miscarriage rates.
Nathan Goodyear

Anti-Inflammatory Effects of Progesterone in Lipopolysaccharide-Stimulated BV-2 Microglia - 0 views

www.ncbi.nlm.nih.gov/...PMC4117574

progesterone inflammation TNF-alpha NF-kappaB hormone hormones LPS microglia

shared by Nathan Goodyear on 29 Aug 14 - No Cached
  • Nathan Goodyear on 29 Aug 14
     
    Progesterone and its anti-inflammatory effects.
Nathan Goodyear

Transdermal progesterone cream for vasomotor ... [Obstet Gynecol. 1999] - PubMed - NCBI - 0 views

www.ncbi.nlm.nih.gov/...10432132

progesterone cream BHRT HRT hormone therapy treatment hot flashes hot flash

shared by Nathan Goodyear on 29 Aug 14 - No Cached
  • Nathan Goodyear on 29 Aug 14
     
    Transdermal BHRT in the form of Progesterone found to reduce hot flashes by 83%.
Nathan Goodyear

http://www.enotes.us/hotflashes2002.pdf - 0 views

www.enotes.us/hotflashes2002.pdf

hot flashes hot flashes vasomotor symptoms female hormones hormone women

shared by Nathan Goodyear on 28 Aug 14 - No Cached
  • Nathan Goodyear on 28 Aug 14
     
    hot flashes.
Nathan Goodyear

Prevalence of Metabolic Syndrome Among College Football Linemen - 0 views

www.canadianjournalofdiabetes.com/...abstract

metabolic syndrome metabolic syndrome college football lineman

shared by Nathan Goodyear on 28 Aug 14 - No Cached
  • Nathan Goodyear on 28 Aug 14
     
    14% of offensive lineman found to have MetS in small study.
Nathan Goodyear

Coronary Artery Calcium Scores: Current Thinking and Clinical Applications - 0 views

www.ncbi.nlm.nih.gov/...PMC2627524

coronary artery calcium cardiovascular disease heart health risk

shared by Nathan Goodyear on 27 Aug 14 - No Cached
  • Nathan Goodyear on 27 Aug 14
     
    coronary artery calcium scores
Nathan Goodyear

Nerve growth factor receptor immunoreactivit... [Mech Ageing Dev. 1993] - PubMed - NCBI - 0 views

www.ncbi.nlm.nih.gov/...8377526

alpha GPC alpha-GPC brain aging l-alpha-glycerylphosphorylcholine

shared by Nathan Goodyear on 27 Aug 14 - No Cached
  • Nathan Goodyear on 27 Aug 14
     
    alpha-GPC appears to increase nerve growth factor receptors in rat brains. 
Nathan Goodyear

Behavioral effects of L-alpha-glycer... [Pharmacol Biochem Behav. 1992] - PubMed - NCBI - 0 views

www.ncbi.nlm.nih.gov/...1574535

brain learning memory cognition alpha GPC alpha-GPC l-alpha-glycerylphosphorylcholine

shared by Nathan Goodyear on 27 Aug 14 - No Cached
  • Nathan Goodyear on 27 Aug 14
     
    animal study finds improvement in learning and memory with alpha-GPC after 20 days of therapy.
Nathan Goodyear

Effect of treatment with choline alphoscerate on h... [Brain Res. 2006] - PubMed - NCBI - 0 views

www.ncbi.nlm.nih.gov/...16989788

alpha-GPC alpha GPC brain cerebrovascular disease glial aging

shared by Nathan Goodyear on 27 Aug 14 - No Cached
  • Nathan Goodyear on 27 Aug 14
     
    alpha-GPC, in rat model found to protect brain from glial reaction damage in cerebrovascular disease.
Nathan Goodyear

Multicentre study of l-alpha-glyceryl-ph... [Drugs Aging. 1993 Mar-Apr] - PubMed - NCBI - 0 views

www.ncbi.nlm.nih.gov/...8477148

alpha GPC alpha-GPC Acetyl-L-carnitine dementia Alzheimer's disease aging brain

shared by Nathan Goodyear on 27 Aug 14 - No Cached
  • Nathan Goodyear on 27 Aug 14
     
    alpha-GPC and to a lesser degree acetyl-l-carnitine improved dementia in multi-center trial.
Nathan Goodyear

Fructose consumption: potential mechanisms for its effects t... : Current Opinion in Li... - 0 views

journals.lww.com/...tial_mechanisms_for_its.5.aspx

fructose insulin resistance lipids triglycerides fat adipose tissue adipose

shared by Nathan Goodyear on 27 Aug 14 - No Cached
  • Nathan Goodyear on 27 Aug 14
     
    fructose leads to direct increase in lipid liver load, post prandial hypertriglyceridemia, and hepatic insulin resistance.
Nathan Goodyear

Functional Properties and Genomics of Glucose Transporters - 0 views

www.ncbi.nlm.nih.gov/...PMC2435356

glucose transporters GLUT fructose metabolism

shared by Nathan Goodyear on 27 Aug 14 - No Cached
  • Nathan Goodyear on 27 Aug 14
     
    Good discussion of Glucose transporters--GLUT.
Nathan Goodyear

Fructose: A Key Factor in the Development of Metabolic Syndrome and Hypertension - 0 views

www.hindawi.com/...682673

fructose uric acid metabolic syndrome sugar

shared by Nathan Goodyear on 24 Aug 14 - No Cached
  • HFCS consists of fructose and glucose mixed in a variety of concentrations, but most commonly as 55% fructose and 45% glucose
  • In the United States, HFCS and sucrose are the major sources of fructose in the diet, and HFCS is a major ingredient in soft drinks, pastries, desserts, and various processed foods
  • fructose and glucose are metabolized in completely different ways and utilize different GLUT transporters
  • ...9 more annotations...
  • In the liver, fructose bypasses the two highly regulated steps of glycolysis, catalyzed by glucokinase/hexokinase and phosphofructokinase both of which are inhibited by increasing concentrations of their byproducts. Instead, fructose enters the pathway at a level that is not regulated and is metabolized to fructose-1-phosphate primarily by fructokinase or ketohexokinase
  • Fructokinase has no negative feedback system, and ATP is used for the phosphorylation process. As a result, continued fructose metabolism results in intracellular phosphate depletion, activation of AMP deaminase, and uric acid generation which is harmful at the cellular level
  • Uric acid, a byproduct of fructose degradation,
  • Uric acid inhibits endothelial NO both in vivo and in vitro, [15] and directly induces adipocyte dysfunction
  • Serum uric acid increases rapidly after ingestion of fructose, resulting in increases as high as 2 mg/dL within 1 hour
  • Uncontrolled fructose metabolism leads to postprandial hypertriglyceridemia, which increases visceral adipose deposition. Visceral adiposity contributes to hepatic triglyceride accumulation, protein kinase C activation, and hepatic insulin resistance by increasing the portal delivery of free fatty acids to the liver
  • Several reviews have concluded that intake of both fructose and HFCS by children and adults was associated with an increased risk of obesity and metabolic syndrome
  • Sucrose is a disaccharide that is comprised of fructose and glucose
  • Figure 2
  • Nathan Goodyear on 24 Aug 14
     
    great read and review of the role of fructose in metabolic syndrome.
Nathan Goodyear

Prevalence of Hyperuricemia and the Relationship between Serum Uric Acid and Metabolic ... - 0 views

www.jstage.jst.go.jp/..._article

uric acid metabolic syndrome triglycerides waist circumference hormones hormone inflammaiton

shared by Nathan Goodyear on 27 Aug 14 - No Cached
  • Nathan Goodyear on 27 Aug 14
     
    Waist circumference and triglycerides correlate with serum uric acid levels.  Men in this study had higher hyperuricemic rates compared to women.  Elevated uric acid levels were associated with increased MetS in both sexes and higher normal uric acid levels were also associated with a higher risk of MetS.
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