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The Ketogenic Diet and Sport: A Possible Marriage? : Exercise and Sport Sciences Reviews - 0 views

  • It is important to note that, although the blood level of glucose drops, it still remains at a physiological level (23), which is maintained through gluconeogenesis involving glucogenic amino acids and also glycerol released from triglycerides
  • “physiological ketosis” where KB levels may rise to 7 to 8 mmol L-1 (but without any pH change). In “pathological diabetic ketoacidosis,” on the other hand, ketonemia can exceed 20 mmol L-1 and also cause lowering of blood pH
  • in the initial phase of KD, about 16% of glucose comes from glycerol (released from triglyceride hydrolysis) and the bulk (60–65 g) from proteins via gluconeogenesis (proteins may be of either dietary or endogenous origin
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  • the protein supply consumed during a KD “preserves,” as demonstrated, lean body mass
  • The importance of glycerol as a glucose source increases progressively during ketosis; in fact, glycerol passes from supplying 16% of total glucose to an average of 60% after many days (>7 d) of complete fasting (from 38% in lean individual to 79% in the obese).
  • The possible reasons for the effectiveness of KD for weight loss may be listed as follows, in order of evidence, strongest first: Figure 3Image Tools 1. Appetite reduction: protein satiety, effects on appetite-related hormones such as ghrelin, and possibly a sort of direct appetite-blocking effect of KB 2. Reduced lipogenesis and increased fat oxidation 3. A reduction in respiratory quotient may indicate a greater metabolic efficiency in fat oxidation 4. A thermic effect of proteins and increased energy usage by gluconeogenesis
  • all data regarding biochemical and molecular mechanisms suggest that it is very difficult to increase muscle mass during a KD; use of which really should be limited to the few days immediately before competition in bodybuilding.
  • a long-term KD can interfere with some muscle hypertrophy mechanisms and this could be counterproductive if the aim of the athlete is to gain muscle mass
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    Great read on the ketogenic  and its application to sports/training...
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Peripheral endocannabinoid signaling controls hyperphagia in western diet-induced obesity - 0 views

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    New study how the Western diet acts like a drug in the body.
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Metabolic characteristics of keto-adapted ultra-endurance runners - Metabolism - Clinic... - 0 views

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    For endurance athletes, low carb and high fat diet utilizes the high fat oxidation in these athletes compared to a high carb diet.  Glycogen stores did not differ between the two groups.  
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Metabolic characteristics of keto-adapted ultra-endurance runners - Metabolism - Clinic... - 0 views

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    full study of previous abstract: low carb and high fat diet found to maintain muscle glycogen equal to high carb diet in endurance athletes.  Endurance athletes have high fat oxidation and this probably only applies to these endurance athletes; I would suspect this high fat oxidation would not be found in other short interval sports i.e. sprinting, football....
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Effect of low-fat diet on female sex hormone levels. - PubMed - NCBI - 0 views

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    low fat diet drops estrogen levels precipitously in women.  It also dropped Testosterone levels.
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Substituting whole grains for refined grains in a 6-wk randomized trial has a modest ef... - 0 views

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    small study finds diet rich in whole grains compared to refined grains improves gut bacteria balance and immune system.  Maybe the key to optimal gut health is the diet?
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The therapeutic imp... [Prostaglandins Leukot Essent Fatty Acids. 2004] - PubMed - NCBI - 0 views

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    mild ketogenic diets have many therapeutic benefits.  This is in contrast to the chronic ketogenic diets of today.  This is a mild ketosis.
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effects of beta-hydroxybutyrate on cognition in memory-impaired adults - 0 views

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    Those with Alzheimer's disease have associated dysfunction of glucose metabolism in the brain, particularly in the hippocampus. It has been reported that a ketogenic diet can improve cognitive function in these individuals. In this study, the ketone bodies were initiated through a diet high in medium chain fatty acids. The ketone bodies served as an alternative fuel source for the brain.
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JAMA Network | JAMA: The Journal of the American Medical Association | Effects of Dieta... - 0 views

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    small study shows that low carb results in greater calories burned in weight loss.  The least calories burned goes to low fat diet.  Many, many studies have show the negative benefits of a low fat diet.
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'Metabolic syndrome' in the brain: deficiency in omega-3 fatty acid exacerbates dysfunc... - 0 views

  • n-3 deficient diet and fructose interventions disrupted insulin receptor signalling in hippocampus as evidenced by a decrease in phosphorylation of the insulin receptor and its downstream effector Akt
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    rats fed high fructose diet and omega-3 diet found to have memory decline.  The purpose of this study was to look at the effects of Metabolic syndrome on the brain.
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Dietary Strategies for Improving Post-Prandial Glucose, Lipids, Inflammation, and Cardi... - 0 views

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    Diet can be a direct cause of inflammation.  A anti-inflammatory diet is a must in those with chronic, inflammatory diseases.    In this study, triglycerides, oxidative stress, and inflammation was found immediately after a single meal of saturated fat.
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JAMA Network | JAMA: The Journal of the American Medical Association | Low-Fat Dietary ... - 0 views

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    The women's health initiative dietary modification trial of almost 50,000 women found no association between a low fat diet and a reduction of colorectal cancer.  Translation: a low fat diet does not lower the risk of colorectal cancer.
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Hypothalamic Inflammation: Marker or Mechanism of Obesity Pathogenesis? - 0 views

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    High fat diet, hypothalamic inflammation and obesity.  Also referenced as metabolic endotoxemia.  Inflammation as a result of a high fat diet results in central inflammation and results in obesity.
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Dietary Macronutrient Content Alters Cortisol Metabolism Independently of Body Weight C... - 0 views

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    Extra-adrenal cortisol production is increased by 11-Beta-HSD1 via low Carb diet.  This is counter to that seen in mice studies.  The fat content of the diet could explain this.  This study looked at men.
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Combined Diet and Physical Activity Promotion Programs to Prevent Type 2 Diabetes Among... - 0 views

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    Meta analysis does find that diet and exercise (lifestyle changes) do reduce risk of diabetes.
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The combined effects of exercise and foods in preventing neurological and cognitive dis... - 0 views

  • The most prevalent types of cognitive impairments include disturbances in attention and learning and memory function
  • An association between BDNF and learning and memory was found when measuring the performance of rats on the Morris water maze task
  • exercise and BDNF have been associated with reducing depression and promoting cognitive enhancement.
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  • In addition to reducing oxidative stress and inflammation, DHA serves to improve neuronal function by supporting synaptic membrane fluidity
  • Curcumin has also been shown to protect the hippocampus and to counteract learning impairment
  • insufficient DHA in the brain can compromise neuronal function with subsequent effects on a broad range of neurological and behavioral faculties.
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    diet and exercise increases BDNF.  Diets rich in omega 3, curcumin, and polyphenols increase BDNF and thus increase neuroplasticity and associated cognition.   In contrast, sugar and saturated fats in crease oxidative stress and worsened spatial learning.  This study is a review.  
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Nutritional Modulation of Insulin Resistance - 0 views

  • Five branched chain and aromatic amino acids (isoleucine, leucine, valine, tyrosine, and phenylalanine) showed significant associations with future diabetes
  • there is increasing evidence that longer term high-protein intake may have detrimental effects on insulin resistance [68, 117–123], diabetes risk [69], and the risk of developing cardiovascular disease
  • high-protein and the high GI diets significantly increased markers of low-grade inflammation
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  • significant and clinically relevant worsening of insulin sensitivity with an isoenergetic plant-based high-protein diet
  • healthy humans that are exposed to amino acid infusions rapidly develop insulin resistance
  • longer term high-protein intake has been shown to result in whole-body insulin resistance [68, 118], associated with upregulation of factors involved in the mammalian target of rapamycin (mTOR)/S6K1 signalling pathway [68], increased stimulation of glucagon and insulin within the endocrine pancreas, high glycogen turnover [118] and stimulation of gluconeogenesis [68, 118].
  • it was recently shown in a large prospective cohort with 10 years followup that consuming 5% of energy from both animal and total protein at the expense of carbohydrates or fat increases diabetes risk by as much as 30% [69]. This reinforces the theory that high-protein diets can have adverse effects on glucose metabolism.
  • Another recent study showed that low-carbohydrate high-protein diets, used on a regular basis and without consideration of the nature of carbohydrates or the source of proteins, are also associated with increased risk of cardiovascular disease [70], thereby indicating a potential link between high-protein Western diets, T2DM, and cardiovascular risk.
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    macronutrient intake and effect on glucose regulation and thus metabolism.
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Excessive caloric intake acutely causes oxidative stress, GLUT4 carbonylation, and insu... - 0 views

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    Just abstract available, but small study finds men fed high calorie typical in western diets results in GLUT4 inactivation in t think that diet needs a long interval to show effects
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A low-glycemic-load diet improves symptoms in acne vulgaris patients: a randomized cont... - 0 views

  • The improvement in acne and insulin sensitivity after a low-glycemic-load diet suggests that nutrition-related lifestyle factors may play a role in the pathogenesis of acne
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    low-glycemic diet improves acne
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Home Remedies: Longevity Tips - Kindle edition by John Okeniyi. Health, Fitness & D... - 0 views

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    Are you struggling with the fact that you really don't know anything about how to get into shape? If you're busy living in yesterday's errors, many of your decisions will be founded on guilt and shame instead of what you really want (and need) to accomplish to achieve your goals. Real change comes from day-to-day choices and becoming mindful and basing your choices on what you need now (rather than what you did or didn't do yesterday) will make your exercise life much more passable. What if I can offer you a solution that will help you to attain greatness, to become a success and learn about the best ways to get in shape? In this book, you will learn about: - Navigate the Astral Plane - MIRROR MADNESS - The Health Zen - Vitamin Vitality - Native American Healing - Boost your Health with Gua Sha - Beautiful Body Essential - Secret of Food Combination - Lose Weight Fasting - Child Diet - many other useful things!
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    Are you struggling with the fact that you really don't know anything about how to get into shape? If you're busy living in yesterday's errors, many of your decisions will be founded on guilt and shame instead of what you really want (and need) to accomplish to achieve your goals. Real change comes from day-to-day choices and becoming mindful and basing your choices on what you need now (rather than what you did or didn't do yesterday) will make your exercise life much more passable. What if I can offer you a solution that will help you to attain greatness, to become a success and learn about the best ways to get in shape? In this book, you will learn about: - Navigate the Astral Plane - MIRROR MADNESS - The Health Zen - Vitamin Vitality - Native American Healing - Boost your Health with Gua Sha - Beautiful Body Essential - Secret of Food Combination - Lose Weight Fasting - Child Diet - many other useful things!
  •  
    Are you struggling with the fact that you really don't know anything about how to get into shape? If you're busy living in yesterday's errors, many of your decisions will be founded on guilt and shame instead of what you really want (and need) to accomplish to achieve your goals. Real change comes from day-to-day choices and becoming mindful and basing your choices on what you need now (rather than what you did or didn't do yesterday) will make your exercise life much more passable. What if I can offer you a solution that will help you to attain greatness, to become a success and learn about the best ways to get in shape? In this book, you will learn about: - Navigate the Astral Plane - MIRROR MADNESS - The Health Zen - Vitamin Vitality - Native American Healing - Boost your Health with Gua Sha - Beautiful Body Essential - Secret of Food Combination - Lose Weight Fasting - Child Diet - many other useful things!
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