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Nathan Goodyear

Sex hormones as immunomodulators in heal... [Int Immunopharmacol. 2001] - PubMed - NCBI - 0 views

www.ncbi.nlm.nih.gov/...11407317

Lupus SLE inflammation Sex hormones hormone Estradiol Testosterone

shared by Nathan Goodyear on 31 Jul 13 - No Cached
  • Nathan Goodyear on 31 Jul 13
     
    Estradiol in mice predisposed to Lupus have increased inflammation and characteristics of Lupus.  In contrast, Estradiol in those without predisposition, do not.  Clearly this is an inflammatory signaling problem.  Studies have shown an Interferon gamma signaling deficit in those with Lupus.  Testosterone decreases the above inflammation signaling.
fnfdoc

How Lupus Affects The Health? - 0 views

www.fnfdoc.com/...lupus-affects-health

Lupus SLE

shared by fnfdoc on 29 Apr 18 - No Cached
  • fnfdoc on 29 Apr 18
     
    SLE or Lupus is an autoimmune disease that causes inflammation of the organs and swelling of the joints. It has vast effects on the renal, skeletal, gastrointestinal and blood systems. It affects mostly people of Chinese and African origin and presents in a capricious and unpredictable manner.
  • fnfdoc on 09 May 18
     
    10 May Is Lupus Day We Must Know About Lupus
Nathan Goodyear

Restoration of regulatory and effector T cell balance and B cell homeostasis in systemi... - 0 views

www.ncbi.nlm.nih.gov/...PMC3580532

vitamin d vitamin D T reg Th17 inflammation autoimmune disease lupus SLE

shared by Nathan Goodyear on 31 Jul 13 - No Cached
  • Nathan Goodyear on 31 Jul 13
     
    Vitamin D support provides benefit in those with Lupus.  The proposed mechanism is through the balance of Treg cells and Th17 cells.  This imbalance plays a role in the etiology of autoimmune disease and those with autoimmune disease, such as in Lupus, frequently have low vitamin D levels.
Nathan Goodyear

http://onlinelibrary.wiley.com/store/10.1002/art.11105/asset/11105_ftp.pdf;jsessionid=4... - 0 views

onlinelibrary.wiley.com/...4193903EA1042174A607429.f03t01

Lupus Testosterone DHEA Progesterone autoimmune disease

shared by Nathan Goodyear on 25 May 16 - No Cached
  • Nathan Goodyear on 25 May 16
     
    good review of sex hormones and LUPUS; whether it is causative or not, sex hormones trends exist in LUPUS i.e. low DHEA in both sexes, low progesterone in women, and low Testosterone in women>men.
Nathan Goodyear

Alterations in circulating fatt... [JPEN J Parenter Enteral Nutr. 2011] - PubMed - NCBI - 0 views

www.ncbi.nlm.nih.gov/...21378249

omega 3 omega-3 n-3 fish oil fish oil Lupus fatty acids EPA DHA

shared by Nathan Goodyear on 30 Oct 13 - No Cached
  • Nathan Goodyear on 30 Oct 13
     
    The purpose of this post is not that prednisone should be used to improve the fatty acid profile in those with Lupus.  That is ridiculous.  But, that fatty acid abnormalities are consistently found in Lupus and particularly omega-3 fatty acids should be evaluated.
Nathan Goodyear

Oxidant stress, ant... [Prostaglandins Leukot Essent Fatty Acids. 1997] - PubMed - NCBI - 0 views

www.ncbi.nlm.nih.gov/...9089797

SLE lupus EPA DHA n-3 omega 3 omega-3 fish oil fish oil fatty acids

shared by Nathan Goodyear on 30 Oct 13 - No Cached
  • Nathan Goodyear on 30 Oct 13
     
    low EPA and DHA found in patients with Lupus.  The authors of this article went so far as to say that lipid peroxides, NO, and anti-oxidants should be a part of the work up for patients with Lupus.
Nathan Goodyear

Drug-induced lupus: an update. [Lupus. 2006] - PubMed result - 0 views

www.ncbi.nlm.nih.gov/...17153847

drug-induced lupus

shared by Nathan Goodyear on 19 Feb 11 - No Cached
  • DILE has been accepted as a side effect of therapy with over 80 drugs since its first description in association with sulfadiazine in 1945.
  • Nathan Goodyear on 19 Feb 11
     
    drug-induced Lupus found in > 80 drugs
Nathan Goodyear

Profile of sex hormones in male patients with systemic lupus erythematosus. - PubMed - ... - 0 views

www.ncbi.nlm.nih.gov/...10866095

lupus autoimmune disease low T low Testosterone Testosterone male hormones male men

shared by Nathan Goodyear on 25 May 16 - No Cached
  • Nathan Goodyear on 25 May 16
     
    low Testosterone trends in some men with Lupus.  The authors conclude it may be causative in some men and not in others.
Nathan Goodyear

Sex hormones in male patients with systemic lupus erythematosus: a comparison with othe... - 0 views

www.ncbi.nlm.nih.gov/...6439564

lupus Testosteorne male hormones hormones men male low T low Testosterone

shared by Nathan Goodyear on 25 May 16 - No Cached
  • Nathan Goodyear on 25 May 16
     
    low Testosterone found in men with Lupus; the authors conclude is is more associative with chronic disease.
Nathan Goodyear

Systemic lupus erythematosus: sex hormones in male patients. - PubMed - NCBI - 0 views

www.ncbi.nlm.nih.gov/...8305925

low T low Testosterone lupus men male male hormones hormones Testosterone autoimmune disease

shared by Nathan Goodyear on 25 May 16 - No Cached
  • Nathan Goodyear on 25 May 16
     
    more men with lupus have low Testosterone compared to controls in small study.
Nathan Goodyear

[Hormonal changes in fertile women with quiescent systemic lupus erythematosus] - Abstr... - 0 views

europepmc.org/...7669873

lupus SLE autoimmune disease autoimmune disease progesterone hormones

shared by Nathan Goodyear on 23 Mar 16 - No Cached
  • Nathan Goodyear on 23 Mar 16
     
    Abstract suggests that low progesterone plays a role in Lupus.
Nathan Goodyear

Treg and lupus -- Bonelli et al. 69 (Suppl 1): i65 -- Annals of the Rheumatic Diseases - 0 views

ard.bmj.com/...i65.abstract

T reg Lupus autoimmune disease inflammation

shared by Nathan Goodyear on 31 Jul 13 - No Cached
  • Nathan Goodyear on 31 Jul 13
     
    Just the abstract available.  Lupus disease found to have low Treg cells.  This would be a proposed mechanism of lost in peripheral tolerance.
Nathan Goodyear

Menstrual and hormonal alterations in juvenile systemi... [Lupus. 2009] - PubMed - NCBI - 0 views

www.ncbi.nlm.nih.gov/...19074167

progesterone low Lupus SLE juvenile hormone hormones

shared by Nathan Goodyear on 30 Oct 13 - No Cached
  • Nathan Goodyear on 30 Oct 13
     
    low Progesterone and progesterone "disturbances" found to be common in juvenile Lupus.  The authors in this study proposed it was due to low follicular reserves.  The point is that low progesterone increases inflammatory cytokines.
Nathan Goodyear

Association between low 25-hydroxyvitamin D, insulin r... [Lupus. 2014] - PubMed - NCBI - 0 views

www.ncbi.nlm.nih.gov/...25216653

vitamin D vitamin D insulin insulin resistance BMI women lupus

shared by Nathan Goodyear on 15 Sep 14 - No Cached
  • Nathan Goodyear on 15 Sep 14
     
    low Vitamin D associated with insulin resistance in women with Lupus.  This was found to be independent of weight.  
Nathan Goodyear

Dehydroepiandrosterone suppresses interleukin 10 synthesis in women with systemic lupus... - 0 views

www.ncbi.nlm.nih.gov/...PMC1754850

dehydroepiandrosterone interleukin Lupus

shared by Nathan Goodyear on 05 Jan 11 - No Cached
  • Nathan Goodyear on 05 Jan 11
     
    DHEA lowers Lupus Flares in CHinese women
Nathan Goodyear

Neurotoxic lupus autoantibodies alter brain function through two distinct mechanisms - 0 views

www.pnas.org/...18569.abstract

lupus brain function neurotoxic autoantibodies

shared by Nathan Goodyear on 03 Mar 11 - No Cached
  • Nathan Goodyear on 03 Mar 11
     
    neurotoxic effects in clients with Lupus
Nathan Goodyear

Drug-induced lupus erythematosus. [Autoimmunity. 2005] - PubMed result - 0 views

www.ncbi.nlm.nih.gov/...16373256

Lupus drug-induced

shared by Nathan Goodyear on 19 Feb 11 - No Cached
  • More than 80 drugs have been associated with DILE.
  • Nathan Goodyear on 19 Feb 11
     
    Drug induced Lupus
Nathan Goodyear

[Drug-induced lupus erythematosus and systemic lup... [Przegl Lek. 2007] - PubMed result - 0 views

www.ncbi.nlm.nih.gov/...18409355

drug induced lupus

shared by Nathan Goodyear on 19 Feb 11 - No Cached
  • Since that time over 80 medications are known to be responsible for development of the disease.
  • Nathan Goodyear on 19 Feb 11
     
    Drug-induced Lupus
Nathan Goodyear

ENVIRONMENTAL LUPUS SYNDROMES - 0 views

rheumatology.oxfordjournals.org/...597.full.pdf+html

drugs and lupus syndromes

shared by Nathan Goodyear on 16 Mar 11 - No Cached
  • Nathan Goodyear on 16 Mar 11
     
    over 70 drugs implicated in lupus syndromes
Nathan Goodyear

Drug-Related Lupus - NEJM - 0 views

www.nejm.org/...NEJM198806023182209

drug induced lupus

shared by Nathan Goodyear on 16 Mar 11 - No Cached
  • Nathan Goodyear on 16 Mar 11
     
    Drug induced lupus exceeds 70 known drugs
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