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Nathan Goodyear

JAMA Network | JAMA Neurology | Refractory Nonmotor Symptoms in Male Patients With Park... - 0 views

archneur.jamanetwork.com/article.aspx

testosterone Parkinson's Parkinson's disease therapy low T treatment inflammation neurodegenerative disease excitotoxicity neurology male

shared by Nathan Goodyear on 21 May 13 - No Cached
  • Nathan Goodyear on 21 May 13
     
    Testosterone therapy aids symptoms of Parkinson's disease.  Whether low T is an associated finding or plays a role has yet to be determined.  However, we do know that androgens play an anti-inflammatory role in men and we know that inflammation plays a role in the neurodegenerative disease that is Parkinson's disease.
Nathan Goodyear

VITAMINS AND ENTACAPONE IN LEVODOPA-INDUCED HYPERHOMOCYSTEINEMIA: A RANDOMIZED CONTROLL... - 0 views

www.neurology.org/...1440.extract

Levodopa parkinson's disease Parkinson's homocysteine neurodegenerative disease vitamins

shared by Nathan Goodyear on 26 Jun 12 - No Cached
  • Nathan Goodyear on 26 Jun 12
     
    It appears that Levodopa administration in those with Parkinson's disease will deplete methylation (SAMe), and thus increase homocysteine, which is a neurotoxin.  Additionally, depletion of methylation is associated with depression, commonly seen in Parkinson's disease
Nathan Goodyear

Lower low density lipid cholesterol levels are associated with Parkinson's disease - 0 views

www.ncbi.nlm.nih.gov/...PMC1906875

LDL cholesterol Parkinson's Parkinson's disease statins Parkinsons disease brain health low density cholesterol

shared by Nathan Goodyear on 19 Mar 15 - No Cached
  • Nathan Goodyear on 19 Mar 15
     
    Lower LDL levels associated with increased risk of Parkinson's disease.  LDL levels < 113 were associated with a 3.5 fold increase in Parkinson's disease compared to LDL of 138.
Nathan Goodyear

Erectile Function and Risk of Parkinson's Disease - 0 views

aje.oxfordjournals.org/...1446.short

ED erectile dysfunction Parkinson's parkinson's disease inflammation

shared by Nathan Goodyear on 21 May 13 - No Cached
  • Nathan Goodyear on 21 May 13
     
    ED associated with a 3.8 x increase in Parkinson's disease.
Nathan Goodyear

Randomized, double-blind, pilot evaluation of int... [Mov Disord. 2009] - PubMed - NCBI - 0 views

www.ncbi.nlm.nih.gov/...19230029

IV glutathione therapy treatment Parkinson's disease

shared by Nathan Goodyear on 14 Dec 11 - No Cached
  • Nathan Goodyear on 14 Dec 11
     
    IV glutathione shown to be same and provide mild improvement in Parkinson's disease.  This is a small pilot study, but a good place to start.  The likelyhood is that glutathione is more beneficial early in Parkinson's disease to slow disease progression.
Nathan Goodyear

Advanced Glycation End Products in Alzheimer's Disease and Other Neurodegenerative Dise... - 0 views

www.ncbi.nlm.nih.gov/...PMC1853056

AGE advanced glycation end products AGE's neurodegenerative disease Alzheimer's disease alzheimer's Parkinson's parkinson's disease Parkinson's

shared by Nathan Goodyear on 11 Jun 12 - No Cached
  • Nathan Goodyear on 11 Jun 12
     
    AGE's, advanced glycation end products, play a role in development/progression of neurodegenerative diseases such as Alzheimer's, Parkinson's...
Nathan Goodyear

Mitochondrial dysfunction in Parkinson's disease. [Biochim Biophys Acta. 2010] - PubMed... - 0 views

www.ncbi.nlm.nih.gov/...19733240

mitochondrial dysfunction Parkinson's Disease

shared by Nathan Goodyear on 16 May 11 - No Cached
  • nhibitor of complex I of the electron transport chain can induce parkinsonism
  • any lines of evidence suggest that mitochondrial dysfunction plays a central role in the pathogenesis of Parkinson's disease (PD)
  • Nathan Goodyear on 16 May 11
     
    Mitochondrial dysfunction in Parkinson's Disease
Nathan Goodyear

The emerging role of nutrition in Parkinson's disease - 0 views

www.ncbi.nlm.nih.gov/...PMC3945400

nutrition disease Parkinson's disease Parkinson's

shared by Nathan Goodyear on 18 Oct 17 - No Cached
  • Nathan Goodyear on 18 Oct 17
     
    Good review of the current data on the role of nutrition in Parkinson's disease.  Take home, a lot of data is conflicting.  But the figure at the end does well to summarize: diet rich in polyphenols in fruits/veggies, carotenoids, resveratrol, Vitamin C, D, E, and MUFA and PUFA are neuroprotective compared to dairy being neurodegenerative.
Nathan Goodyear

ScienceDirect.com - Journal of Clinical Neuroscience - Testosterone improves motor func... - 0 views

www.sciencedirect.com/...S0967586805003875

Parkinson's parkinson's disease testosterone neuroscience disease motor symptoms

shared by Nathan Goodyear on 21 May 13 - No Cached
  • Nathan Goodyear on 21 May 13
     
    Testosterone shown to improve motor skills in people suffering from Parkinson's disease.  
Nathan Goodyear

Exposure to pesticides or solvents and risk of Parkinson disease - 0 views

www.neurology.org/...2035.abstract

pesticides disease Parkinson's Parkinson's disease solvents environmental toxins toxins paraquat

shared by Nathan Goodyear on 01 Jun 13 - No Cached
  • Nathan Goodyear on 01 Jun 13
     
    meta-analysis finds that exposure to pesticide and solvents increase Parkinson's disease by 80%.  One potentially problematic pesticide was paraquat.
Nathan Goodyear

Effect of DHEA on recovery of muscle atro... [J Korean Acad Nurs. 2011] - PubMed - NCBI - 0 views

www.ncbi.nlm.nih.gov/...22310868

DHEA Parkinson's disease Parkinson's

shared by Nathan Goodyear on 02 Jun 13 - No Cached
  • Nathan Goodyear on 02 Jun 13
     
    DHEA improves muscle atrophy in Parkinson's disease.
Nathan Goodyear

Exposure to pesticides or solvents and risk of Parkinson disease - 0 views

www.neurology.org/...2035

pesticides Parkinson's disease PD Parkinson's disease

shared by Nathan Goodyear on 18 Jun 13 - No Cached
  • Nathan Goodyear on 18 Jun 13
     
    Meta-analysis finds link between insecticides and Parkinson's disease.  This is not a political issue.  This is science.
Nathan Goodyear

PLOS ONE: N-Acetyl Cysteine May Support Dopamine Neurons in Parkinson's Disease: Prelim... - 0 views

journals.plos.org/...article

Parkinsons Parkinson's disease NAC N-acetylcysteine brain

shared by Nathan Goodyear on 17 Jun 16 - No Cached
  • Nathan Goodyear on 17 Jun 16
     
    pilot study finds that NAC protects the dopaminergic neurons in the brains in cell line stud.  Clinical found increased dopamine binding in the brain compared to placebo in individuals with Parkinson's disease.
Nathan Goodyear

Glutathione and Parkinson's Disease - ACAM Integrative Medicine (IM) Blog - 0 views

acam.typepad.com/...ne-and-parkinsons-disease.html

IV glutathione Parkinson's disease treatment therapy

shared by Nathan Goodyear on 14 Dec 11 - No Cached
  • Nathan Goodyear on 14 Dec 11
     
    IV glutathione therapy as adjuvant in people with Parkinson's disease
Nathan Goodyear

Redox imbalance in Parkinson's disease. [Biochim Biophys Acta. 2008] - PubMed - NCBI - 0 views

www.ncbi.nlm.nih.gov/...18358848

Parkinson's disease ROS oxidative stress dopamine

shared by Nathan Goodyear on 14 Dec 11 - No Cached
  • Nathan Goodyear on 14 Dec 11
     
    oxidative stress and Parkinson's disease
Nathan Goodyear

Glutathione, iron and Parkinson's disease. [Biochem Pharmacol. 2002] - PubMed - NCBI - 0 views

www.ncbi.nlm.nih.gov/...12213603

Glutathione Parkinson's neurodegenerative disease Iron Fe

shared by Nathan Goodyear on 14 Dec 11 - No Cached
  • Nathan Goodyear on 14 Dec 11
     
    Glutathione restoration should be an important role in people with Parkinson's Disease
Nathan Goodyear

Neuroinflammation in Parkinson's disease: a ta... [Lancet Neurol. 2009] - PubMed - NCBI - 0 views

www.ncbi.nlm.nih.gov/...19296921

glial cells Parkinson's disease neurodegenerative disorders inflammation neuroinflammation

shared by Nathan Goodyear on 14 Dec 11 - No Cached
  • Nathan Goodyear on 14 Dec 11
     
    activated glial cells play important role in Parkinson's disease and other neuroimflammatory diseases
Nathan Goodyear

Study Suggests Coenzyme Q10 Slows Functional Decline in Parkinson's Disease: National I... - 0 views

www.ninds.nih.gov/...kinsons_coenzymeq10_101402.htm

CoQ10 Parkinson's disease Huntington's ecitotoxic neurotoxic

shared by Nathan Goodyear on 07 Nov 11 - Cached
  • Nathan Goodyear on 07 Nov 11
     
    high dose CoQ10 shown to slow disease progression in Parkinson's disease.  A similar study had shown the same finding in Huntington's disease.  Both are excitotoxic diseases
Nathan Goodyear

Reduced intravenous glutathione in the treatment of early parkinson's disease 10.1016/S... - 0 views

www.sciencedirect.com/...S0278584696001030

IV intravenous glutathione Parkinson's disease PD

shared by Nathan Goodyear on 09 Mar 12 - No Cached
  • Nathan Goodyear on 09 Mar 12
     
    IV glutathione shown to slow profession of Parkinson's Disease.  IV was given at doses of 600 mg IV twice daily for 30 days.
Nathan Goodyear

Low LDL cholesterol and increased risk of Parkins... [Mov Disord. 2008] - PubMed - NCBI - 0 views

www.ncbi.nlm.nih.gov/...18381649

LDL cholesterol Parkinson's parkinson's disease neurodegenerative disease

shared by Nathan Goodyear on 14 Jun 12 - No Cached
  • Nathan Goodyear on 14 Jun 12
     
    individuals with the lowest LDL associated with a 350% increase rate of Parkinson's disease.
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