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Nathan Goodyear

EWG Report || BodyBurden 2 - The Pollution in Newborns - 0 views

  • Tests revealed a total of 287 chemicals in the group.
  • Of the 287 chemicals we detected in umbilical cord blood, we know that 180 cause cancer in humans or animals, 217 are toxic to the brain and nervous system, and 208 cause birth defects or abnormal development in animal tests
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    Body Burden - The Pollution in Newborns
Nathan Goodyear

Delivery mode shapes the acquisition and structure of the initial microbiota across mul... - 0 views

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    Study finds infants born vaginally have gut flora similar to mother's vaginal flora--Lactobacillus, Prevotella, or Sneathia species.  In contrast, those born via C/S have gut flora similar to that on the skin surface--staphylococcus, corynebacterium...
Nathan Goodyear

The risks of selective serotonin reuptake inhibitor use in infertile women: a review of... - 0 views

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    There is just no reason to take SSRIs during pregnancy.  SSRIs increase risk of miscarriage, birth defects, preterm birth, newborn behavior problems, pulmonary hypertension...All women considering pregnancy should removed, yet SSRIs are prescribed as if they are candy.
indiacardiacsurg

Fitness Articles - Child Heart Hospital India Provides a Complete Range of Service for... - 0 views

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    Approximately 1% of all newborns are born with more or less severe heart defects. Ultimately, without therapy, these heart deficiencies can damage the heart so significantly that it may not fulfill its tasks. Call us: +91-9370586696 Mail us: enquiry@indiacardiacsurgerysite.com
Nathan Goodyear

Exposure of Newborn Male and Female Rats to Environmental Estrogens: Delayed and Sustai... - 0 views

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    xenoestrogen exposure has been shown to increase ER alpha and ER beta in the pituitary.
Nathan Goodyear

Bisphenol A Promotes Human Prostate Stem-Progenitor Cell Self-Renewal and Increases In ... - 0 views

  • these findings show that estrogen stimulates human prostate epithelial stem cell self-renewal and progenitor cell amplification (prostasphere size), with the greatest effects observed at lower E2 doses.
  • Similar to E2, BPA increased prostasphere number and size with significant and maximal effects observed at 10 nM BPA
  • Taken together, these results provide strong evidence that, similar to E2, BPA increases stem cell self-renewal and progenitor amplification in normal human prostate epithelial cells
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  • these findings provide further support that E2 and BPA maintain the stem-like state within the normal prostate epithelial cell population
  • Our previous findings demonstrated that normal prostate stem-progenitor cells within the prostaspheres expressed ERα and ERβ, implicating them as direct targets for E2 and BPA action
  • p-Akt and p-Erk, well established downstream targets of membrane-associated ERs
  • BPA and E2 had equimolar capacity for activation of these rapid signaling pathways in human prostaspheres, thus identifying a dynamic and robust signaling pathway initiated by low-dose BPA exposure in prostate stem-progenitor cells.
  • these findings indicate that both rapid membrane-initiated estrogen action and genomic ER signaling pathways are operative in human prostate progenitor cells.
  • these results document the fact that levels of bioactive BPA in the present study are similar to levels found in human umbilical cord blood and newborns in the general population
  • the present findings identify for the first time that in vivo exposure of the human prostate epithelium to low doses of BPA significantly increases the susceptibility of the human prostate epithelium to hormonal carcinogenesis.
  • The current study provides clear evidence that, similar to E2, normal human prostate stem and progenitor cells are direct targets for BPA action
  • Both hormones increased stem-like cell numbers in primary prostate epithelial cultures in a dose-dependent manner and augmented the number and size of 3-D cultured prostaspheres, markers of stem cell self-renewal and progenitor cell proliferation, respectively
  • signaling pathways engaged by estrogens through these separate receptors are multiple and complex, including both membrane-initiated signaling and genomic activation via ER transcriptional activity
  • Estrogen action is mediated by ERα and ERβ
  • the current results indicate that developmental exposure to BPA, at doses routinely found in humans, significantly increases the cancer risk in human prostate epithelium in response to elevated estrogen levels in an androgen-supported milieu. Because relative estrogen levels rise in aging men, we suggest that humans may be susceptible to BPA-driven prostate disease in a manner similar to that in the rodent models.
  • We propose that early-life perturbations in estrogen signaling including inappropriate exposure to BPA have the potential to amplify and modify the stem-progenitor cell populations within the human prostate gland and, in so doing, alter the normal homeostatic mechanisms that maintain a growth neutral state throughout life
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    Bisphenol A exposure in utero found to increase prostate cancer risk later in life.  This exposure occurred at typical life exposure levels as found in umbilical cord blood sampling,  This occurred through stem cell self-renewal and progenitor amplification
Nathan Goodyear

Cambridge Journals Online - Abstract - Effect of vitamin D supplementation during pregn... - 0 views

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    Vitamin D3 during pregnancy shown to have only positive effects on pregnancy.  Granted this is a small study with only 3 doses of small amounts of vitamin D3.  But still positive.
Nathan Goodyear

Mercury Levels in Newborns and Infants After Receipt of Thimerosal-Containing Vaccines - 0 views

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    good letter to the editor on the accumulation of inorganic Hg in the brain from Thimerosal.
Mirage Marketing

Surrogacy in india information-SCI Healthcare - 1 views

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    SCI Healthcare and Isis Hospital SCI Healthcare and Isis Hospital and Multispecialty Centre are dedicated to assisting infertile couples from around the world become parents. Our sole aim is to provide our clients with world-class medical facilities and expertise at competitive prices, delivered with compassion and care. We exist solely to help infertile couples experience the joy of holding their newborn baby in their arms. http://surrogacycentreindia.com
Nathan Goodyear

Serum levels of sex hormone-binding globulin (SHBG) are not associated with lower level... - 0 views

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    Age increases SHBG.  This study doesn't find a correlation with non-SHBG Testosterone in "health" men.  The term health is probably key.
Nathan Goodyear

Mechanisms of cannabidiol neuroprotection in hypoxic-ischemic newborn pigs: Role of 5HT... - 0 views

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    Another animal study finds CBD is neuroprotective.  This study actually found that CBD reduced excitotoxicity, inflammation, and oxidative stress.
indiacardiacsurg

Child Heart Surgeon in India Will Create a Healthy Tomorrow for Children and Their Fami... - 0 views

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    The cost of pediatric cardiac surgery in India remains low even when additional prices which include boarding, hotel charges, and length of stay at the hospital are taken into account. Since the cost of getting the best price for child heart surgery in India is less, hundreds of people from all around the world travel to India each year with the hope to get treated without any financial burden. Get Fast Track Query Reply just call us at +91-9370586696 or Email us: enquiry@indiacardiacsurgerysite.com
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