Histamine and histamine intolerance - 0 views
ajcn.nutrition.org/...1185.long
histamine histamine intolerance DAO diamine oxidase HNMT methylation
shared by Nathan Goodyear on 24 Mar 15
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Histamine intolerance can develop through both increased availability of histamine and impaired histamine degradation
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increased availability may be an endogenous histamine overproduction caused by allergies, mastocytosis, bacterias, gastrointestinal bleeding, or increased exogenous ingestion of histidine or histamine by food or alcohol
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Other biogenic amines, such as putrescine, may also be involved in displacing histamine from its mucosal mucine linkage, which results in an increase of free absorbable histamine in circulation
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the main cause of histamine intolerance is an impaired enzymatic histamine degradation caused by genetic or acquired impairment of the enzymatic function of DAO or HNMT