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Nathan Goodyear

Probiotics for the treatment of a... [Ann Allergy Asthma Immunol. 2008] - PubMed - NCBI - 0 views

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    A meta analysis of 12 randomized controlled trials found that 9 found improvement in allergies and asthma with probiotics.   A lot of studies have looked at probiotics and the prevention of allergies and asthma, but this meta analysis shows probiotics should be used as a part of therapy.
Nathan Goodyear

Season of birth and food allergy ... [Ann Allergy Asthma Immunol. 2010] - PubMed - NCBI - 0 views

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    vitamin D deficiency in mother and season of birth  impacts allergy risk of baby
Nathan Goodyear

Autoimmune disease and allergy are controlle... [In Vivo. 1994 Mar-Apr] - PubMed - NCBI - 0 views

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    IV Vitamin C treatment lowers inflammation in those with autoimmune disease and allergies.  This response is, however, short lived.
Nathan Goodyear

Histamine and histamine intolerance - 0 views

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    Histamine intolerance?  Can the massive increase in allergies and thus histamine release be creating problems with metabolism of histamine?  Or can some people struggle with inborn deficits of diamine oxidase?  
wheelchairindia9

Tynor Anklet Pair - 0 views

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    Tynor Anklet (Pair) Anklets are tubular supports widely used in orthopedic practice to provide mild compression, warmth & support to the ankle joint, to allay pain and inflammation generally associated with old age, arthritis, sports etc. Four way stretch Two layered fabric Hypoallergenic Uniform compression Simple pull on application Tynor Anklet (Pair) Features Bilayered , cotton on the inside Dermophillic interpahse with the skin Better sweat absorption Better comfort Better patient compliance. No allergies or rash Bilayered, nylon on the outside Ensures long life Excellent aesthetics Color fastness. Two layers enclose air space retains body heat effectively Provides therapeutic warmth and assuring support to the knee. Four-way stretchable seamless tubular fabric Effective compression Enhanced comfort. No vaso constriction. Adjusts compression even on uneven diameters Simple pull on application improves patient compliance. Tynor Anklet (Pair) Measurements Measure circumference approx 2 inches above the ankle joint. Size Chart - Size Inches CM Small 7.2-8.4 18-21 Medium 8.4-9.6 21-24 Large 9.6-10.8 24-27 XL 10.8-12 27-30
beautesante

Allergie au printemps, petits gestes contre l'allergie au pollen - 0 views

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    Picotements des yeux, éternuements ou maux de tête : le printemps n'est pas encore là, mais son lot d'allergies est déjà bien présent. En cause : les pollens.
Nathan Goodyear

Influence of mode of delivery on gut microbiota composition in seven year old children ... - 0 views

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    fascinating read.  This study looked at the mode of delivery and found that the balance of bifidobacterium and clostridium gut microbiota was altered by mode of delivery.  This has been associated with excessive IgE antibody production.  Ever wonder why we have so many allergies today?  Maybe it is because of the doctors rush to perform Ceserean Sections.
Nathan Goodyear

Health Information - Grande Dunes Surgery Center - 0 views

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    Food Allergies and Sensitivities
Nathan Goodyear

PosterSessionOnline - 0 views

  • Poster number: 552 No. visits: 16 Title: ALCAT test results in the treatment of gastrointestinal symptoms Authors : Mara De Amici , Centre: Foundation IRCCS Hospital San Matteo
  • Poster number: 553 No. visits: 12 Title: Evaluation of ALCAT test results in the non IgE-mediated pathology of the skin Authors : Mara De Amici , Centre: Foundation IRCCS Hospital San Matteo
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    Recent Poster presentation at European Academy of Allergy and Clinical Immunology reveals 66 % improvement in skin conditions with ALCAT diet.  Read poster #552
wheelchairindia9

Tynor Cervical Collar Hard Adjustable - 0 views

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    Tynor Cervical Collar Hard Adjustable Cervical Collar Hard Adjustable is used for supporting, immobilizing or adjusting the neck in the flexion, extension, or hyperextension position. Recommended where a rigid immobilization of the cervical region is required. Anatomical shape. Comfortable edge padding. Adjustable height. Slight weight. Latex free. Tynor Cervical Collar Hard Adjustable Features Edge padding by ethafoam Better cushioning and comfort long functional life Light in weight No leaching no allergy Better cushioning and comfort Anatomically designed with height adjustment Ensures perfect fitting Improves immobilsation Enhances comfort Perforated Better ventilation Enhances comfort Better patient compliance. High quality PE Sheet Ensures rigid support Long life of the collar Improves aesthetics. Tynor Cervical Collar Hard Adjustable Measurements Measure distance between edge of sternum and lower jaw with neck in extension position.
wheelchairindia9

Tynor Cervical Collar Soft - 0 views

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    Tynor Cervical Collar Soft Cervical collar soft is used for supporting the neck and protecting it against jerks impacts and vibrations. Recommended where a partial or controlled immobilization of the cervical region is required. Ultimate comfort. Partial immobilization. Optimal support. Excellent aesthetics. Absorbs impact. Tynor Cervical Collar Soft Features Soft polyurethane Provides unmatched comfort, used as prophylactic collar, reduces pain and provides comfortable support during traveling. Covered with hypoallergenic cotton stockinet. Better patient comfort, no allergy or rash even to sensitive skin, better compliance No hard, bony reinforcement Improves patient comfort, particularly recommended for geriatric patients, excellent for prolonged use. Anatomical design Uniform support to the mandible, effective action and better fit, better comfort. Perforated collar body Improved ventilation, more patient comfort, better compliance.
wheelchairindia9

Hernia Belt - 0 views

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    Tynor Hernia Belt Hernia belt offers a gentle and constant relief from reducible inguinal hernia by providing adjustable and comfortable pressure to the hernia. On wearing the belt the occurrence of herniation gets eliminated. Tynor hernia belt is available in skin color, can be worn inconspicuously under clothing. Moulded foam pads. Adjustable leg and abdominal strap. Soft and skin friendly materials. Controlled pressure. Tynor Hernia Belt Features Anatomic pads Presses the inguinal aperture at the appropriate angle, enhances the effectiveness. Molded out of special grade ethafoam Appropriate hardness, light weight, smooth and comfortable. Grey color product Can be worn inconspaciously under cloth, aesthetically pleasing. Soft and dermophilic materials No rash no allergy, very comfortable, improve compliance. Adjustable pelvic and leg straps One size fits a large population, controlled & customized pressure possible. Tynor Hernia Belt Measurements Measure circumference around the waist 2 inches below the navel.
SEO Husain

Asthma information | Asthma Homeopathic Treatment - Dr. Batra's - 0 views

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    Asthma makes breathing difficult for more than 300 million people worldwide according to the WHO. Treat your bronchial asthma/ breathlessness/ wheezing/ respiratory allergy with Homeopathy at Dr. Batra's
Nathan Goodyear

Curcumin attenuates the development of allergic airway inflammation and hyper-responsiv... - 0 views

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    curcumin shown to inhibit allergic airway inflammation, through NF-kappaB inhibition.  This has implications in asthma flares.
wheelchairindia9

Ankle Support - 0 views

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    Tynor Knee Cap Pair Knee Caps are tubular supports widely used in orthopaedic practice to provide mild compression warmth & support to the limbs and joints, to allay pain and inflammation, generally associated with old age, arthritis, sports injury etc. Hypoallergenic Four way stretch Uniform compression Simple pull on application Tynor Knee Cap (Pair) Features Bilayered , cotton on the inside Dermophillic interpahse with the skin Better sweat absorption Better comfort Better patient compliance. No allergies or rash Bilayered, nylon on the outside Ensures long life Excellent aesthetics Color fastness. Two layers enclose air space retains body heat effectively Provides therapeutic warmth and assuring support to the knee. Four-way stretchable seamless tubular fabric Effective compression Enhanced comfort. No vaso constriction. Adjusts compression even on uneven diameters
wheelchairindia9

Cervical Collar Soft Firm Density - 0 views

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    Cervical Collar Soft Firm Density Cervical Collar Soft (Firm Density) is used for supporting, immobilizing or adjusting the neck in the flexion, extension, or hyperextension position. Recommended where a partial or controlled immobilization of the cervical region is required. Ultimate comfort Effective immobilization Strong support Excellent aesthetics Long life. Cervical Collar Soft Firm Density Features Made of very high density (60 kg./m3) P.U. foam High immobilization, better support , quick relief, no reinforcement, more comfortable, long life. Anatomical design Uniform support to the mandible, Better immobilization, Better comfort Covered with hypoallergenic cotton stockinet Better patient comfort, no allergy or rash even to sensitive skin. Better compliance Perforated collar body Improved ventilation , more patient comfort, better compliance. Fawn colored stockinette Matches skin color, Better aesthetics. Long hook-loop closure tape Ensure snug fitting around neck, easy application and quick removal.
wheelchairindia9

Cervical Orthosis Philadelphia Ethafoam - 0 views

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    Cervical orthosis Ethafoam is an advanced collar with scientific design which ensures complete immobilization on one hand and perfect comfort on the other. It is called as a gold standard in cervical immobilization. Ultimate comfort. Perfect immobilization. Anatomically moulded. Minimal contact surface. Hypoallergenic. Cervical Orthosis (Philadelphia) Ethafoam Features Pre-formed chin Provides rest to the chin, ensures comfort, improves immobilization. Anatomical and balloon design Offers perfect immobilization, minimal contact of the neck, allows use in burn or trauma patients. Hypoallergenic materials Ensures no rash or allergy even on prolonged use, compatible to geriatrics, better patient compliance . Tracheotomy opening Compatible to use of endotracheal tube, improves air ventilation, improves patient comfort and compliance. Two piece design Easy application, firm occipital support, option for varying rigidity. Ethafoam Light weight, better patient compliance, non absorbent ensures easy cleaning and maintenance.
wheelchairindia9

Tynor Cervical Orthosis Plastazote - 0 views

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    Tynor Cervical Orthosis Plastazote Cervical orthosis plastazote is an advanced collar with scientific design which ensures complete immobilization on one hand and perfect comfort on the other, It is called as a gold standard in cervical immobilization. Ultimate comfort. Perfect immobilisation. Anatomically moulded. Minimal contact surface. Hypoallergenic. Tynor Cervical Orthosis (Philadlphia) Plastazote Features Pre-formed chin Provides rest to the chin, ensures comfort, improves immobilization. Anatomical and balloon design Offers perfect immobilization, minimal contact of the neck, allows use in burn or trauma patients. Plastazote Light weight, better patient compliance. Non absorbent ensures easy cleaning and maintenance Hypoallergenic, Ensures no rash or allergy even to old age patients Eco friendly manufacturing process Better patient compliance Tracheotomy opening Compatible to use of endo tracheal tube, improves air ventilation. Improves patient comfort and compliance. Two piece design Easy application, firm occipital support, option for varying rigidity. Better immobilization Tynor Cervical Orthosis (Philadlphia) Plastazote Measurements Measure distance between edge of sternum and lower jaw with neck in extension position.
trungtamnamkhoa

Pimples In The Penis - What Is The Cause? - 1 views

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    The penis gets pimples, white or red items make men worried because they don't know the cause. In most of the causes of penile acne, the group of causes of sexually transmitted diseases is the most dangerous. Genital skin is very sensitive, especially in the penis. Only a small change can cause abnormal symptoms such as tumors, irritation, irritation and discomfort. Men need to understand the reasons for effective prevention and treatment. Group of allergy causes: Men with acne in the penis due to local allergies, for example, the penis skin has been exposed to "strange" substances from poor quality condoms. In addition, wearing underwear that is too tight, fabric material is not guaranteed or new clothes bought without washing well and many dust and dirt also cause irritation and penile pimples. Eating allergenic foods can also irritate the skin and, if unfortunately, the skin is as delicate as the "genital area".
Nathan Goodyear

How is the Immune System Suppressed by Cancer - 1 views

  • nitric oxide (NO) released by tumor cells
  • Excellent work by Prof de Groot of Essen, indicated by adding exogenous xanthine oxidase ( XO) in hepatoma cells, hydrogen peroxide was produced to destroy the hepatoma cells
  • NO from eNOS in cancer cells can travel through membranes and over long distances in the body
  • ...43 more annotations...
  • NO also is co linked to VEGF which in turn increases the antiapoptotic gene bcl-2
  • The other important influence of NO is in its inhibition of the proapoptoic caspases cascade. This in turn protects the cells from intracellular preprogrammed death.
  • nitric oxide in immune suppression in relation to oxygen radicals is its inhibitory effect on the binding of leukocytes (PMN) at the endothelial surface
  • Inhibition of inducible Nitric Oxide Synthase (iNOS)
  • NO from the tumor cells actually suppresses the iNOS, and in addition it reduces oxygen radicals to stop the formation of peroxynitrite in these cells. But NO is not the only inhibitor of iNOS in cancer.
  • Spermine and spermidine, from the rate limiting enzyme for DNA synthases, ODC, also inhibit iNOS
  • tolerance in the immune system that decreases the immune response to antigens on the tumors
  • Freund’s adjuvant
  • increase in kinases in these cells which phosphorylate serine, and tyrosine
  • responsible for activation of many growth factors and enzymes
  • phosphorylated amino acids suppress iNOS activity
  • Hexokinase II
  • Prostaglandin E2, released from tumor cells is also an inhibitor of iNOS, as well as suppressing the immune system
  • Th-1 subset of T-cells. These cells are responsible for anti-viral and anti-cancer activities, via their cytokine production including Interleukin-2, (IL-2), and Interleukin-12 which stimulates T-killer cell replication and further activation and release of tumor fighting cytokines.
    • Nathan Goodyear
       
      Th1 cells stimulate NK and other tumor fighting macrophages via IL-2 and IL-12; In contrast, Th2, which is stimulated in allergies and parasitic infections, produce IL-4 and IL-10.  IL-4 and IL-10 inhibit TH-1 activation and the histamine released from mast cell degranulation upregulates T suppressor cells to further immune suppression.
  • Th-2 subset of lymphocytes, on the other hand are activated in allergies and parasitic infections to release Interleukin-4 and Interleukin-10
  • These have respectively inhibitory effects on iNOS and lymphocyte Th-1 activation
  • Mast cells contain histamine which when released increases the T suppressor cells, to lower the immune system and also acts directly on many tumor Histamine receptors to stimulate tumor growth
  • Tumor cells release IL-10, and this is thought to be one of the important areas of Th-1 suppression in cancer patients
  • IL-10 is also increased in cancer causing viral diseases such as HIV, HBV, HCV, and EBV
  • IL-10 is also a central regulator of cyclooxygenase-2 expression and prostaglandin production in tumor cells stimulating their angiogenesis and NO production
  • nitric oxide in tumor cells even prevents the activation of caspases responsible for apoptosis
    • Nathan Goodyear
       
      NO produced by cancer cells inhibits proapoptotic pathways such as the caspases.
  • early stages of carcinogenesis, which we call tumor promotion, one needs a strong immune system, and fewer oxygen radicals to prevent mutations but still enough to destroy the tumor cells should they develop
  • later stages of cancer development, the oxygen radicals are decreased around the tumors and in the tumor cells themselves, and the entire cancer fighting Th-1 cell replication and movement are suppressed. The results are a decrease in direct toxicity and apoptosis, which is prevented by NO, a suppression of the macrophage and leukocyte toxicity and finally, a suppression of the T-cell induced tumor toxicity
  • cGMP is increased by NO
  • NO in cancer is its ability to increase platelet-tumor cell aggregates, which enhances metastases
  • the greater the malignancies and the greater the metastatic potential of these tumors
  • The greater the NO production in many types of tumors,
  • gynecological
  • elevated lactic acid which neutralizes the toxicity and activity of Lymphocyte immune response and mobility
  • The lactic acid is also feeding fungi around tumors and that leads to elevated histamine which increases T-suppressor cells.  Histamine alone stimulates many tumor cells.
    • Nathan Goodyear
       
      The warburg effect in cancer cells results in the increase in local lactic acid production which suppresses lymphocyte activity and toxicity as well as stimulates histamine production with further stimulates tumor cell growth.
  • T-regulatory cells (formerly,T suppressor cells) down regulate the activity of Natural killer cells
  • last but not least, the Lactic acid from tumor cells and acidic diets shifts the lymphocyte activity to reduce its efficacy against cancer cells and pathogens in addition to altering the bacteria of the intestinal tract.
  • intestinal tract bacteria in cancer cells release sterols that suppress the immune system and down regulate anticancer activity from lymphocytes.
  • In addition to the lactic acid, adenosine is also released from tumors. Through IL-10, adenosine and other molecules secreted by regulatory T cells, the CD8+ cells can be inactivated to an anergic state
  • Adenosine up regulates the PD1 receptor in T-1 Lymphocytes and inhibits their activity
  • Adenosine is a purine nucleoside found within the interstitial fluid of solid tumors at concentrations that are able to inhibit cell-mediated immune responses to tumor cells
  • Adenosine appears to up-regulate the PD1 receptor in T-1 Lymphocytes and inhibits the immune system further
  • Mast cells with their release of histamine lower the immune system and also stimulate tumor growth and activate the metalloproteinases involved in angiogenesis and metastases
  • COX 2 inhibitors or all trans-retinoic acid
  • Cimetidine, an antihistamine has been actually shown to increase in apoptosis in MDSC via a separate mechanism than the antihistamine effect
    • Nathan Goodyear
       
      cimetidine is an H2 blocker
  • interleukin-8 (IL-8), a chemokine related to invasion and angiogenesis
  • In vitro analyses revealed a striking induction of IL-8 expression in CAFs and LFs by tumor necrosis factor-alpha (TNF-alpha)
  • these data raise the possibility that the majority of CAFs in CLM originate from resident LFs. TNF-alpha-induced up-regulation of IL-8 via nuclear factor-kappaB in CAFs is an inflammatory pathway, potentially permissive for cancer invasion that may represent a novel therapeutic target
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    Great review of the immunosuppression in cancer driven by the likes of NO.
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