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Nathan Goodyear

Histamine and histamine intolerance - 0 views

  • Histamine intolerance can develop through both increased availability of histamine and impaired histamine degradation
  • increased availability may be an endogenous histamine overproduction caused by allergies, mastocytosis, bacterias, gastrointestinal bleeding, or increased exogenous ingestion of histidine or histamine by food or alcohol
  • Other biogenic amines, such as putrescine, may also be involved in displacing histamine from its mucosal mucine linkage, which results in an increase of free absorbable histamine in circulation
  • ...2 more annotations...
  • the main cause of histamine intolerance is an impaired enzymatic histamine degradation caused by genetic or acquired impairment of the enzymatic function of DAO or HNMT
  • The main enzyme for metabolism of ingested histamine is diamine oxidase (DAO)
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    good discussion of histamine and histamine intolerance.  All centers around diamine oxidase function (DAO).
Nathan Goodyear

Histamine and histamine intolerance - 0 views

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    Histamine intolerance?  Can the massive increase in allergies and thus histamine release be creating problems with metabolism of histamine?  Or can some people struggle with inborn deficits of diamine oxidase?  
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