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Nathan Goodyear

International Journal of Impotence Research - PDE5 inhibitors beyond erectile dysfunction - 0 views

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    Good review on phosphodiesterase 5 inhibitors.
Nathan Goodyear

Study finds impotence risk higher in men taking several drugs: MedlinePlus - 0 views

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    Study reveals that the more medications a man takes, the more symptoms of ED he has.  This was found to be independent from variables such as hypertension, diabetes...  ED symptoms started at 1 medication
Nathan Goodyear

International Journal of Impotence Research - Treatment of testosterone-induced gynecom... - 0 views

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    arimidex, also known as anastrozole, is shown to be an effective aromatase inhibitor in men.  These case studies used arimidex to successfully stimulate testosterone production by limiting testosterone to estrogen production.  This was found to be useful in the treatment of gynecomastia.
Nathan Goodyear

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1700586/pdf/brmedj02278-0080b.pdf - 0 views

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    case study from years ago that finds pesticide exposure caused impotence in 4 agriculture workers.  
Nathan Goodyear

International Journal of Impotence Research - Mechanisms of action of PDE5 inhibition i... - 0 views

  • Nitric oxide (NO) is produced from oxygen and L-arginine under the control of nitric oxide synthase (NOS)
  • Cyclic GMP is the intracellular trigger for penile erection
  • PDE5 is the predominant phosphodiesterase in the corpus cavernosum
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    Nice review of the mechanism of action of PDE5 inhibitors and ED.
Nathan Goodyear

Androgens and sexual function: a placebo-controll... [Aging Male. 2009] - PubMed - NCBI - 0 views

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    This study found no benefit from DHEA at 50 mg twice daily for those with androgen deficiency and sexual dysfunction.
Nathan Goodyear

International Journal of Impotence Research - Low testosterone levels are associated wi... - 0 views

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    low Testosterone found to be associated with increased CAD in men.
Nathan Goodyear

International Journal of Impotence Research - Abstract of article: Epidemiology: testos... - 0 views

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    low Testosterone shown to be associated with insulin resistance, poor glucose control, elevated HgbA1c, and obesity
Nathan Goodyear

Increased estradiol levels in venous... [Int J Impot Res. 2005 May-Jun] - PubMed - NCBI - 0 views

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    Study finds a link between Estradiol, venous insufficiency, and ED in men.  The signaling is through VEGF and NO.
Nathan Goodyear

Testosterone, SHBG and cardiovascula... [Int J Impot Res. 2010 Mar-Apr] - PubMed - NCBI - 0 views

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    Higher Testosterone and low SHBG  in postmenopausal women is associated with increased CVD risk
Nathan Goodyear

Access : Testosterone, SHBG and cardiovascular health in postmenopausal women : Interna... - 0 views

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    Review finds that low SHBG and higher Testosterone levels are associated with increased CVD risk in post menopausal women.  Exact relationship is undetermined.
Nathan Goodyear

Metabolic syndrome and risk for ED: a meta-a... [Int J Impot Res. 2014] - PubMed - NCBI - 0 views

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    Metabolic syndrome associated with increased risk of ED in men in meta-analysis.  This points to ED as a metabolic condition.
Nathan Goodyear

International Journal of Impotence Research - Abstract of article: Influence of demogra... - 0 views

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    Study finds little link to Testosterone replacement therapy to elevation in PSA in "healthy" men.  All the members of this study had negative prostate biopsies prior to therapy.
Nathan Goodyear

Epidemiology: testosterone and the metabolic syndr... [Int J Impot Res. 2007 Mar-Apr] -... - 0 views

  • testosterone may have a protective role in the development of metabolic syndrome and subsequent diabetes mellitus and cardiovascular disease in aging men
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    low Testosterone as part of therapy in those with metabolic syndrome
Nathan Goodyear

Occupational Lead Poisoning - February 15, 1998 - American Family Physician - 0 views

  • The freely diffusible plasma fraction is distributed extensively throughout tissues, reaching highest concentrations in bone, teeth, liver, lungs, kidneys, brain and spleen
  • Inorganic lead does not undergo any metabolic transformation or digestion in the intestines, or detoxification in the liver.5
  • With chronic exposure over a long period of time, most absorbed lead ends up in bone
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  • The total bodily content of lead is called the body burden; in a steady state, about 90 percent of the body burden is bound to bone.2
  • n general, lead is excreted quite slowly from the body (with the biologic half-life estimated at 10 years). Since excretion is slow, accumulation in the body occurs easily.2
  • hronic toxicity is an insidious illness with protean manifestations.3,6 Symptoms may include arthralgias, headache, weakness, depression, loss of libido, impotence and vague gastrointestinal difficulties.
  • Late effects may include chronic renal failure, hypertension, gout and chronic encephalopathy.6
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    occupational lead poisoning
Nathan Goodyear

Effect of raising endogenous testosterone levels in impotent men with secondary hypogon... - 0 views

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    Small study found that 2 months of clomid therapy increased LH, FSH, total Testosterone, and free Testosterone over placebo.  Improvement in ED was minimal and most in young men.  This is consistent with other studies that have found that less effects are seen in those with multiple comorbidities.
Nathan Goodyear

International Journal of Impotence Research - Clomiphene increases free testosterone le... - 0 views

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    Nice study that looked at climid to restore HPA function and increase Testosterone stimulation and production.  This study also does a good job of reviewing the mechanisms of low T.  Low T is really a biomarker of poor health in men.
Nathan Goodyear

International Journal of Impotence Research - Obesity, low testosterone levels and erec... - 0 views

  • Studies have shown that ED may be an early biomarker of general endothelial dysfunction, atherosclerosis and CVD
  • testosterone treatment of hypogonadal young and older men improves sexual function, increases lean mass and decreases fat mass
  • In men with low serum testosterone (for example, <8 or 230 nmol l−1) with obesity, metabolic syndrome and diabetes mellitus, treatment with testosterone is warranted
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  • In obese middle-aged men, testosterone treatment reduced visceral adipocity, insulin resistance, serum cholesterol and glucose levels
  • testosterone replacement has a favorable impact on body mass, insulin secretion and sensitivity, lipid profile and blood pressure in hypogonadal men with the metabolic syndrome as well as type 2 diabetes mellitus
  • Testosterone significantly inhibits lipoprotein lipase activity, which reduces triglycerides uptake into adipocytes in the abdominal adipose tissue
  • testosterone treatment decreased endogenous inflammatory cytokines (tumor necrosis factor-α and IL-1β) and lipids (total cholesterol) and increased IL-10 in hypogonadal men
  • Testosterone treatment reduced leptin and adiponectin levels in hypogonadal type 2 diabetic men after 3 months of testosterone replacement
  • available data clearly show a relationship between obesity, low testosterone levels and ED
  • Obesity adversely affects endothelial function and lowers serum testosterone levels through the development of insulin resistance and metabolic syndrome
  • Metabolic disturbances as well as production of cytokines and adipokines by inflamed fat cells may be causal factors in the development of ED
  • The onset of ED and the associated risk of CVD may be delayed through lifestyle modifications that affect obesity, such as diet and exercise
  • Very low testosterone levels contribute to the development of ED in obesity, metabolic syndrome and type 2 diabetes mellitus
  • Obesity is associated with low total testosterone levels that can be explained at least partially by lower sex hormone-binding globulin (SHBG) in obese men
  • epidemiological studies have shown a negative correlation between BMI and total testosterone and to a lesser extent with free and bioavailable (biologically active) testosterone levels
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    Obesity is associated with low Testosterone and ED in men.
trungtamnamkhoa

Pharma Injectable Sust 250mg of the faculty Men's Health - 1 views

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    Pharma Sust 250mg injections treat hypogonadism disorders in men, after the illness, impotence due to lack of hormones, menstrual symptoms in men such as reducing sexual pleasure and physiological activities. Side effects: The drug can cause erectile dysfunction, signs of excessive sexual stimulation, reduced sperm count, decreased volume of ejaculation, water & salt retention. In pre-puberty boys: develop sex early, increase the frequency of erectile dysfunction, enlargement of the penis, and early growth of bone heads.
gensehat

Impotensi - Penyebab Dan Pengobatannya. - gensehat - 0 views

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    Impotensi kerap terjadi khususnya oleh pria yang sudah berumur 40 tahun ke atas dan ada beberapa faktor yang melatarbelakanginya baik karena faktor kesehatan maupun psikologis.
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