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Another support point for Estrogen as a cause of low Testosterone.  This animal study points to signaling of Estradiol through ER alpha.  This study found high expression of ER alpha and subsequent signaling by E2 decreased cAMP and Nur77 transcription factor.  Nur77 increases steroid synthesis.  This was confirmed with ER alpha knockout mice.

low Total Testosterone associated with CAD, particularly aortic.  Obviously, Testosterone, when low, is a marker of poor health in men.  However, low Testosterone can likely play a role in disease development, especially when age is factored in--low Testosterone in younger men likely plays an etiology versus a lesser impact in the elder.

Women with elevated androgens, Testosterone and androstenedione, are at higher risk of preeclampsia.  This translates to a higher risk of CVD in women later in life, post pregnancy.  This fits with other literature that CVD is linearly associated with a rising Testosterone.  This has been found in caucasian and black women.

DHEA beneficial at the biochemistry level in asthma.  DHEA inhibits the activation of transcription factor activator protein-1.

Dr Jennifer Martinick reviews the cases of many Hair Loss patients everyday. She has also spread knowledge on factors that causes negative impact on hairs. Read this complete article to know why an experienced Hair Restoration Surgeon is preferred.

Severe sleep apnea associated with lower Testosterone levels and fatigue.  The low level of Testosterone was the only factor predictive of fatigue and reduced activity in sleep apnea.  This was only found in severe sleep apnea, not mild cases.

New study finds autism is mix of genetic and environmental factors.

Estrogen receptors are primarily located inside the nucleus and in the cytoplasm; not on the cell membrane surface. This article specifically focus' on the non-genomic action of ER-beta.  ER-alpha and ER-beta are classic transcription factors.

published ahead of print, so full article is not available.  Abstract points to low T as a result of metabolic factors i.e. obesity, inflammation...This is true.  The authors, in the abstract, point to the differences in Menopause in women versus low T in men.  

Make sure that you actually have a plan when about to purchase infusion pumps. What do you need to use them for? The actual flexibility is a very important factor. Normally, you can find stationary pumps. 

Fascinating study on how the addition of Lactobacillus reuteri increased Testicular size, prevented testicular atrophy, increased serum Testosterone production and protected against diet-induced/obesity-induced hypogonadism.  This was a mouse model

gut micro biome effects spermatogenesis, Testosterone production, and the brain-testicle-barrier.

great review of BDNF and neurogenesis.

BDNF can be found and followed in saliva

This study of inner city men found low T associated with methadone use.  Narcotics are a known risk factor for low T.  The free T was calculated from serum.  This equilibrium dialysis is based on too many variables.  Look at the studies on equilibrium dialysis.  This study also found calculated free T was not associated with insulin resistance.  However, insulin resistance is a peripheral tissue dysfunction not a serum dysfunction.  So, a calculated free T (not reality) in the serum shows me nothing of the peripheral activity.  For example, inflammation has been shown to increase aromatase activity in the prostate tissue only.  The thinking in the conclusions of so many of these studies is soooo flawed.

Wheelchair with comfortble reclining back headrest. This wheelchair allows the user to obtain a more comfortable position, equally for those who are unable to sit at 90 degrees, but need to lie back. Options include elevating legrests and cushioning. This type of Wheelchair is a superb light weight aluminium total care chair with all the actions one would wish. All fully adjustable, tilt in space, reclining back, multi positional headrest,elevating legrests and full pressure cushioning. The reclining deluxe manual wheelchair. This wheelchair has all the features one would need in a wheelchair, fully adjustable arms, legrests, reclining back and pop off wheels. To remove the wheels simply press the button in the centre of the wheel and slide them off. Ideal for those who need to recline in the wheelchair as the back rest on this wheelchair can be adjusted to any position. With cushions, elevating legrests and other options, this wheelchair can be configured to meet most needs. This chair does not have tilt in space mechanism or pressure care cushioning, for this must look to the tilt in space chair. Comfort and positioning tilt-in-space wheelchair which is durable, modern looking and comfortable. It offers adjustable seat height and depth, back height, length adjustable armpads and infinite recline and tilt. The multifunction tilt in space wheelchair focuses heavily on the need of each individual user which is why it has many adjustments in one frame to make sure it can alter to cater individual requirements. One of the main features of this chair is its tilt in space feature, which allows a step less adjustment of the backrest and the seat angle. This is easily operated from the push handle and can be quickly adjusted when needed. The design of the backrest and seating on the wheelchair helps ensure comfort and support for the user. Wheelchair comes with elevating leg rests fitted as standard which again are step less and easily adjusted. There is also the o

Reclining wheelchairs, since the product class is built around one key feature: the capability to adjust the backrest and/or footrest into a reclined position. This feature is especially important to users who find it difficult or impossible to sit in a fully upright position, and users who sleep in their chairs frequently. For those that are looking for a more portable chair. When compared with a similar, non-reclining chair, a reclining wheelchair tends to weigh more and - unlike other manual models - manual wheelchairs that recline typically aren't foldable. reclining wheelchair compensates mechanically for body positioning by automatically readjusting armrests and lateral supports.

Recliner wheelchair is low profile allowing to comfortably fit under tables and desks. Enjoy numerous activities with increased comfort such as stretching, napping and watching television. The ability to recline also improves circulation and the ability for sore spots to heal.

Karma Reclining Wheelchair KM 5000:
The karma reclining wheelchair km-5000 Transport Wheelchair is an ultra lightweight folding aluminum reclining wheelchair. With full length padded armrests, an adjustable height head pillow, and more this wheelchair has added comfort for any user. This chair also features swing-away elevating footrests and adjustable length leg supports and footplates. With a weight of 33 Lbs this chair can be transported with ease.

Karma Reclining Wheelchair KM 5000 Features:
Folding 6061 T-6 Aircraft-grade aluminum frame in black
powder coat finish
Backrest Reclines 90°~163° and includes anti-tippers
Full length padded detachable armrests with side panels
Swing-away detachable elevating footrests
Adjustable length leg supports & footplates
Adjustable-height head pillow
14" Mag wheels with flat free polyurethane tires
7" x 1" Flat free front polyurethane casters
Adjustab

great review of cirrhosis and BCCA supplementation.

good review of BCAA and liver disease: both mechanisms and therapy.

CRP is an independent marker for future cardiovascular disease