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Nathan Goodyear

4-Hydroxytamoxifen binds to and deactivates the estrogen-related receptor γ - 0 views

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    estrogen-related receptors.  There are 3 types: alpha, beta, and gamma.  These don't respond to estrogens, but to estrogen related elements
Nathan Goodyear

Transcriptional targets shared by estrogen receptor-related receptors (ERRs) and estrog... - 0 views

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    estrogen related receptors play a role in estrogen signaling, though they don't bind estradiol. They bind estrogen related elements. Exact role is unknown. They are called "orphan" members of the nuclear family of receptors.
Nathan Goodyear

Regulation of mitochondrial biogenesis by thyroid hormone - 0 views

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    Study describes the T3 effect on mitochondrial biogenesis.  T3 interacts with receptors involved with mitochondrial biogenesis in 3 ways: thyroid hormone receptors (TR), thyroid hormone receptor elements (TRE), and a combination of the two.
Nathan Goodyear

http://www.epa.gov/teach/chem_summ/mercury_elem_summary.pdf - 0 views

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    EPA paper on elemental Mercury
Nathan Goodyear

Estrogen receptor-β regulates human tryptophan hydroxylase-2 through an estro... - 0 views

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    Estradiol upregulates tryptophan hydroxylase and thus serotonin production.  The signaling was via ER beta and estrogen response elements.
arunaraayala

Michael Jackson's Son Won't Follow In Dad's Paths - 0 views

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    alking in an extraordinary interview with the Los Angeles Times newspaper, the prince Jackson expressed: "all of us celebrate I am going to do musical composition and dance. The track is a large voluminous an element of my lifestyles
Willow O'Donnell

Different Criteria to Classify Infusion Pumps By - Scribd - 0 views

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    Infusion pumps can deliver all kinds of liquids. They cannot provide semisolid or solid substances. While they can be used to deliver small amounts of liquids too, they are mostly used for long infusions. All these elements are used to support the body against a deficiency.
Willow O'Donnell

Different criteria to classify infusion pumps by - Slideshare - 0 views

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    Infusion pumps can deliver all kinds of liquids. They cannot provide semisolid or solid substances. While they can be used to deliver small amounts of liquids too, they are mostly used for long infusions. All these elements are used to support the body against a deficiency. For example, patients who are not conscious will actually be fed with infusion pumps.
herbnclay

Calcium Bentonite Clay Benefits - Internal and External Uses - 0 views

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    HERB n' CLAY provides you with 100 percent all natural Calcium Bentonite Clay. Bentonite clay has microscopic layers through which it absorbs the toxins in our bowels. It contains silica with high traces of Calcium. In addition there are more than 50 trace elements in Calcium Bentonite Clay.
fitspresso

https://www.fitspresso-co.com/ - 0 views

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    FitSpresso™ | Official Site fitspresso-co.com FitSpresso Only $39/Bottle Limited Time Offer! FitSpresso Special Deal + Special 51% Discount Save $660 + 180 Days Money Back Guarantee FitSpresso Herpesyl Five Star A dietary product formulated to assist users in reducing weight can increase other advantages that can support overall health. This product can assist users in getting closer to the desirable body weight. Regular Price: 149/per bottle Only for: $39/per bottle Buy Now What IsFitSpresso? FitSpresso is promoted as a natural supplement that comes in the form of diet pills, and it can aid in rapid and efficient weight loss, similar to many other supplements. The term "natural supplements refers to a nutritional supplement that is made entirely of natural, chemical-free materials. You can utilize these organic ingredients to aid in natural weight loss. It can speed up your body's metabolism and assist with other crucial processes. All parts of our bodies are impacted by weight increase, and not only do we need to deal with the increased weight, but we also need to deal with the numerous problems and illnesses that come along with it. This refers to the risk of developing chronic cardiac conditions, low blood pressure, and, in some circumstances, problems with blood sugar. However, FitSpresso even with its bright and bold claims, can help you efficiently manage your weight and completely avoid these extra uncomfortable problems. FitSpresso is a supplement that comes in the form of a pill, which makes it tasty, simple to swallow, and handy. According to the manufacturer, these diet tablets are GMO-free and toxic-free, making them edible. This is why we have things such as weight loss supplements. Thanks to modern advancements, we can just take a dietary supplement pill to bring about significant weight loss in a completely healthy and natural manner. Not only this, but dietary supplements can also support healthy blood sugar levels and help with
spineneuro

How Robotic Spine Surgery in India Attracting Patients From Sudan? ~ Medical Tour to In... - 0 views

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    Affordable robotic spine surgery cost is one of the most distinguished elements for Sudan patients deciding on their spine surgery in India. At the same time, the robotic spine surgery cost is a whole lot much less compared, making it a sensible choice for the patients to travel to India for surgical treatment.
wheelchairindia9

Tynor Ankle Binder - 0 views

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    The boot type walkers can be provided in a fixed mode or with ankle joints to provide articulation. Pneumatic support is also available. The brace has a lightweight, durable, semi rigid shell that will support the limb and provide protection. Incorporated are medial and lateral uprights, heel and rocker sole. Closure is achieved with Velcro. The strapping system provides full circumferential compression of the limb. The breathable fiber liner is washable. The articulated boot allows range of motion (ROM) usually from approximately 20 degrees dorsiflexion to 40 degrees plantar flexion. Tynor Walker Boot is designed by the Tynor to rehabilitate the person after injury or fracture. It allows easy movement as well as supports the ankle and leg. This can be a great substitute for cast and also useful during early cast removal. It can also be used during sprain in the foot and this walker gives great relief to the pain. It can easily do any mild activity. It also works for the persons with a lower leg and will give an equal level of the lower feet as well as reduces the pressure. It effectively enclosed the muscles of the leg or foot during the fracture and gives comfort without disturbing the recovery process. This walker boot is made up from the good quality material. It has Aluminum lateral bars that are corrosion free. It is light in weight and provides enhanced mobility. It gives sturdy support to feet and leg. Its Hook Loop system allows to adjust it according to the comfort. It is also infused with Foam liner and Pad set that gives soft feet and also provides great support. It is available in different sizes. Tynor Walker Boot is designed for rehabilitation after injury, fracture , sprains or surgery of foot, ankle or lower leg. The boots provide support to the ankle and leg without inhibiting mobility. They can be a substitute for cast or can be used in case of early cast removal. With a wider rocker bottom, these boots promote a natural gait, reduced
Nathan Goodyear

elements of oxidation/reduction balance in experimental hypothyroidism - 0 views

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    hypothyroidism decreases antioxidant enzyme activity of SOD and glutathione perioxidase.
Nathan Goodyear

Long-term testosterone therapy in hypogonadal men ameliorates elements of the metabolic... - 0 views

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    Testosterone therapy followed over 5 years in hypogonadal men found physiologic replacement of Testosterone decreased Total cholesterol, decreased LDL, increased HDL, decreased blood pressure, decreased blood glucose, decreased HgbA1c, decreased CRP, ALT, and AST. All men with metabolic syndrome  should have appropriate hormone evaluation done.
Nathan Goodyear

Salivary Testosterone and a Trinucleotide (CAG) Length Polymorphism in the Androgen Rec... - 0 views

  • Testosterone correlated inversely with participant age (r = −0.39, p = 0.012) and positively with number of CAG repeats
  • transactivation potential of the AR appears to decline in graded relation to an increasing number of CAG repeats, which are distributed over a normative range of 11–37 and, in Caucasian populations, commonly average 21–22 repeats
  • When activated by androgens, ARs translocate to the cell nucleus, where they exert transcriptional control of androgen-dependent genes by binding to androgen response elements within gene regulatory sequences
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  • some evidence suggests a high number of CAG repeats may be associated with cognitive aging
  • androgens (like other steroid hormones) promote or repress the expression of genes specifying an array of cellular proteins
  • diurnal variation in testosterone levels
  • salivary testosterone correlated negatively with participant age and positively with CAG length variation in the AR gene
  • CAG repeat number varied inversely with reactivity of the ventral amygdala to facial expressions of negative affect
  • higher salivary testosterone was likewise associated with a greater number of AR CAG repeats
  • relative androgen insensitivity in ARs with a larger number of CAG repeats
  • Because circulating testosterone is regulated via negative feedback through the hypothalamic-pituitary-gonadal axis, diminished androgen sensitivity at higher CAG repeat lengths may reduce feedback suppression of luteinizing hormone (LH). LH would then be maintained at higher levels, in turn promoting higher testosterone production
  • Testosterone up-regulates AVP expression in the amygdala
  • Oxytocin exerts an inhibitory influence on AVP expression in the central amygdala, and the synthesis of oxytocin is mediated by estrogen and estrogen receptors
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    Study used saliva to measure Testosterone levels in men.  Testosterone levels were inversely associated with age, but positively associated with CAG repeat sequences in the AR.
Nathan Goodyear

Leptin Resistance: A Possible Interface of Inflammation and Metabolism in Obesity-Relat... - 0 views

  • The leptin axis has functional interactions with elements of metabolism, such as insulin, and inflammation, including mediators of innate immunity, such as interleukin-6
  • Given that plasma levels of leptin and inflammatory markers are correlated and also predict cardiovascular risk
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    leptin resistance, inflammation and obesity
Nathan Goodyear

Fifty- two-Week Treatment With Diet and Exercise Plus Transdermal Testosterone Reverses... - 0 views

  • there appears to be a positive correlation between serum testosterone levels and insulin sensitivity in men across the full spectrum of glucose tolerance (Pitteloud et al, 2005), and this relationship is at least partially direct and not fully dependent on (changes in) elements of the MetS
  • supervised D&E alone led to significant improvements in testosterone concentrations, glycemic control, and components of the MetS
  • diet control, exercise, and testosterone supplementation may be beneficial in the management of men with T2D
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  • androgen-deprivation therapy in males with prostatic cancer may be associated with an increased risk for T2D, which may be caused by negative effects on insulin sensitivity
  • insulin sensitivity, measured by HOMA, improved in both groups and with a significantly greater degree when testosterone was added to supervised D&E
  • Fasting insulin concentrations, a good representative of insulin sensitivity, did show a significant correlation with changes in circulating androgen levels, an observation in support of Pitteloud et al (2005), who showed a direct relationship between insulin sensitivity and circulating testosterone concentrations using the hyper-insulinemic euglycemic clamp technique
  • 52 weeks of testosterone treatment also significantly improved circulation levels of adiponectin and hsCRP, key serum markers of insulin sensitivity and hepatic steatosis
  • The changes in both adiponectin and hsCRP were significantly correlated with the therapy-induced changes in bioavailable testosterone
  • a negative correlation was found between hsCRP levels and bioavailable testosterone
  • serum PSA concentrations did not differ between the 2 treatment groups, indicating that short-term testosterone administration appears to be acceptably safe
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    Study of men with metabolic syndrome and type II Diabetes finds that diet and exercise alone improved glucose control and metabolic syndrome components by 31%.  The addition of Testosterone therapy increased this % to 81%.
Nathan Goodyear

The trace element selenium and the thyroid gland. - PubMed - NCBI - 0 views

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    Selenium is very important in thyroid function, not just Iodine.  Low Se levels significantly correlate with thyroid cancer.
beautybycagla

healthy skin | Get Beauty Tips On - 0 views

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    As we get older, it is importаnt for us to tаke decent cаre of our skin. Exposure to sunlight аnd elements thаt аre distinct cаn wreаk hаvoc on it. This mаy leаd to premаture аging аnd other skin conditions. A skin cаre routine will surely help keep our skin looking fresh, young аnd hydrаted. These аre importаnt steps thаt you need to do аnd so, without further аdo, here is your guide to some bаsic skin cаre routine.
Nathan Goodyear

An Overview of Melatonin and Breast Cancer | Natural Medicine Journal - 0 views

  • Overall its effect on cancer cells is oncostatic at physiological levels, or cytotoxic at higher concentrations
  • direct antioxidant, antimitotic, antiestrogenic, prodifferentiating and antimetastatic effects have been well characterized
  • hypothalamic-pituitary axis (HPA) and immune system
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  • On a cellular level, melatonin acts as a selective estrogen receptor modulator (SERM) through decreased expression of estrogen receptor alpha and reduction in the ability of estrogen-estrogen receptor alpha (ERα) complex to bind to the estrogen response element (ERE) on DNA
  • Melatonin also acts as a selective estrogen enzyme modulator (SEEM), reducing the activity of aromatase in cells
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    review of melatonins activity in cancer battle.
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