Fuel metabolism in starvation - 0 views
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Nathan Goodyear on 01 Jul 13Great review of the metabolic changes that the body undergoes during calorie restriction/fasting
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Energy Intake and Prostate Tumor Growth, Angiogenesis, and Vascular Endothelial Growth ... - 0 views
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Granted, this is prostate tumor rat model. But, a calorie restriction of 20-40% resulted in reduced tumor growth through inhibition of angiogenesis.
Ketoacids? Good medicine? - 0 views
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Great, great read on how biochemistry effects brain function. Beta-hydroxybutyrate is an alternative fuel source for the brain in times of calorie restriction. This promotes neuroplasticity and neurogenesis without the inflammatory effects of glucose and insulin.
Caloric restriction modulates Mcl-1 expression and sensitizes lymphomas to BH3 mimetic ... - 0 views
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Calorie restriction aids fight against cancer on several fronts. Granted this is a mouse study, but Cancer should be attacked through nutrition just as through surgery and chemo/radiation.
Tissue glutathione as a cyst(e)ine reservoir during f... [J Nutr. 1981] - PubMed - NCBI - 0 views
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glutathione levels decreased in times of fasting. IMplications in diets that involve Low and extremely low calorie intake.
Effect of low-calorie versus low-carbohydrate ketogenic diet in type 2 diabetes. - PubM... - 0 views
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low carb, high fat, ketogenic diet outperformed low calorie diet in people with type II diabetes
Protein Restriction, Epigenetic Diet, Intermittent Fasting as New Approaches for Preven... - 0 views
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Calorie restriction and protein restriction inhibit IGF-1, insulin, AkT, PI3K, and mTOR. In addition, those with protein intake >20%, compared to 10%, was associated with a 4 fold increase in cancer death risk and a 75% increase in overall mortality. Protein restriction inhibits tumor growth, associated with a 30-70% reduction in IGF-1, reduced the accumulation of oxidized proteins. The restriction of tryptophan alone reduced inflammation.
Caloric restriction delays age-related methylation drift | Nature Communications - 0 views
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How does calorie restriction work? Epigenetics.
Primary care-led weight management for remission of type 2 diabetes (DiRECT): an open-l... - 0 views
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study finds very low calorie diet reversed diabetes. The greatest weight loss was associated with greatest remission of diabetes at 86% with >15 kg weight loss.
Reduction of Chronic Hyperinsulinemia (Insulin Resistance) for the Prevention and Treat... - 0 views
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Fasting and calorie restriction are a means to attack hyperinsulinemia and insulin resistance.
ScienceDirect.com - Physiology & Behavior - The effects of a high-energy diet on hippoc... - 0 views
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We have known that diet and brain inflammation were linked. This study shows a link between, what they call High energy diet (better known as high calorie, high fat, high carb...), and altered hippocampus brain function.
Metabolic management of glioblastoma multiforme using standard therapy together with a ... - 0 views
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case study highlights the use of a calorie restricted, ketogenic diet to augment glioblastoma multiforme. In incomplete resection, at 2 months no brain tumor was visualized via PET and MRI.
Caloric restriction improves memory in elderly humans - 0 views
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30% caloric restriction significantly improved memory/cognitive function in elderly.
Pleasure Eating Triggers Body's Reward System and May Stimulate Overeating - 0 views
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Ghrelin plays a role in overeating. This is not much of a surprise as Ghrelin has been shown to be a major appetite driver and has been linked to higher calorie intake of foods.
Cell Host and Microbe - Microbiota Regulate Intestinal Absorption and Metabolism of Fat... - 0 views
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You are what you eat...you are what your gut eats. Confirmation of the influence of the GI microbiota on calorie utilization. We shouldn't be surprised by this: what do we do to cattle? we give them antibiotics which increases their weight and time to market. What are we doing to ourselves?
Is the degree of food processing and convenience linked with the nutritional quality of... - 0 views
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3/4 of calories from moderately/highly process foods in households in new study. Obesity trend won't change if this one fact doesn't change.
Excessive caloric intake acutely causes oxidative stress, GLUT4 carbonylation, and insu... - 0 views
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Just abstract available, but small study finds men fed high calorie typical in western diets results in GLUT4 inactivation in t think that diet needs a long interval to show effects
Akkermansia muciniphila and improved metabolic health during a dietary intervention in ... - 0 views
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akkermansia muciniphila bacteria associated with improved metabolism following calorie restriction in obese adults. Again, gut flora effects metabolism
PLoS ONE: Metabolic and Behavioral Compensations in Response to Caloric Restriction: Im... - 0 views
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exercise and muscle very important to maintaining weight loss long-term. Calorie restriction results in muscle mass loss and this will impair the ability to maintain weight loss long term
http://www.diabetologia-journal.org/files/Narendran.pdf - 0 views
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Exercise is not just for calories out. Exercise increases growth hormone, IGF-1, glucagon-like peptide 1, IL-6, and IL-1ra. The effect is to GH increases beta islet cell mass and protects beta cell lines against IL-1beta, Interferon-gamma and TNF-alhpa induced apoptosis. IL-6 increased production increases GLP-1 and IL-1ra which counters IL-1beta. Interleukin-1beta induces islet cell apoptosis and thus IL-1ra counters this pro-inflammatory signal.
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