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Nathan Goodyear

The Rankings - United Health Foundation - 0 views

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    Tennessee ranks 39 in Health as determined by the United Health Foundation.  I disagree with some of the defining terms in "health", but the point is well taken.
Nathan Goodyear

The Rankings - United Health Foundation - 0 views

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    Louisiana Health rankings as determined by the United Health Foundation.  This 49 ranking is down from 47.  Only Mississippi ranks lower.  Yet, the LSBME is the most restrictive.  Go figure.
arunaraayala

Aamir Khan Announces 2nd Edition of Satyamev Jayate - Locality News - 0 views

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    Aamir Khan, the founder of Paani Foundation, today publicized the second version of Satyamev Jayate ...
Nathan Goodyear

Higher Free Thyroxine Levels Predict Increased Incidence of Dementia in Older Men: The ... - 0 views

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    what a silly study!  They look at free T4, the weakest thyroid hormone and found high levels to be associated with dementia.  However, they failed to assess free T3, the most biologically active, and reverse T3, inactive.  This study was like they intentionally blinded themselves of the body's physiology to study dementia.  This is the problem with a lot of research today: they have forgotten their foundation. Many older adults struggle with poor free T4 to free T3 conversion and high reverse T3 conversion.  So, without knowing what these clients were doing in these pathways makes their conclusion obsolete.
Nathan Goodyear

Relationship Between Healthy Diet and Risk of Cardiovascular Disease Among Patients on ... - 0 views

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    This study proves that the foundation of our current health problem is our diet.  Eat better!  In this study, individuals with CVD, had a significant reduction in recurrent CVD events with a simple change in diet.  The amazing thing it was above and beyond that of medications.
Nathan Goodyear

HE3286 as Treatment for Parkinson's Disease | The Michael J. Fox Foundation - 0 views

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    Synthetic analogue of DHEA metabolite, HE3286, analyzed as treatment in Parkinson.s disease.
Nathan Goodyear

Gut microbiota of healthy Canadian infants: profiles by mode of delivery and infant die... - 0 views

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    Cesarean delivery and lack of breast feeding significantly alter gut flora.  This has potential significant metabolic consequences--diabetes, asthma, obesity...The urge to deliver at convenient times may lay the foundation for our metabolic crisis in the US.
Nathan Goodyear

Neurodegenerative disorders: clues from glutamate ... [Crit Rev Neurobiol. 1996] - PubM... - 0 views

  • glutamate antagonists or agents that improve energy metabolism may slow the degenerative process and offer a therapeutic approach for temporarily retarding the progression of these disabling disorders.
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    Magnesium and Zinc improve neurodegenerative disease via glutamate blockade; Poor energy production at foundation of neurodegenerative disease
Nathan Goodyear

The Relationship between Alzheimer's Disease and Diabetes: Type 3 Diabetes? - ACAM Inte... - 0 views

  • AD has its foundation in neuroendocrinology
  • Referring to AD as type 3 diabetes has its foundation in the fact that the CNS in AD is characterized by a paucity of insulin and resistance of the insulin receptors
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    Insulin/Glucose dysregulation and Alzheimer's disease
Nathan Goodyear

PosterSessionOnline - 0 views

  • Poster number: 552 No. visits: 16 Title: ALCAT test results in the treatment of gastrointestinal symptoms Authors : Mara De Amici , Centre: Foundation IRCCS Hospital San Matteo
  • Poster number: 553 No. visits: 12 Title: Evaluation of ALCAT test results in the non IgE-mediated pathology of the skin Authors : Mara De Amici , Centre: Foundation IRCCS Hospital San Matteo
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    Recent Poster presentation at European Academy of Allergy and Clinical Immunology reveals 66 % improvement in skin conditions with ALCAT diet.  Read poster #552
fnfdoc

Cosmetic Cause Health Problems | Your Health Our Priority - 0 views

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    Personel care items like cosmetic including mascara foundations, body lotions and soaps, hair style products very vital value regarding health and science. Everybody used toxic chemicals in the form of cosmetics. How we take good and healthy steps for good and safe beauty.
pharmacybiz

Dr Nik Kotecha OBE - Distinguished Alumni Award Winner 2022 - 0 views

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    Dr Nik Kotecha OBE, chairman of Morningside Pharmaceuticals and the Randal Charitable Foundation, has won the Distinguished Alumni Award at Imperial College London's Alumni Awards 2022. The annual awards honour outstanding alumni who have demonstrated sustained excellence in their personal and professional achievements and have made a substantial impact on society. Dr Kotecha, who founded Morningside in 1991, which manufactures and supplies generic and branded medicines to the UK and globally, said: "I'm thrilled to be honoured by the university in this way. "As a child growing up in Leicester my family had very little, but I was fortunate to be given opportunities to gain a good education. After finishing my degree in Newcastle; Professor Steve Ley FRS at Imperial College took a chance in accepting me into his eminent group and this really was the opportunity I needed to forge a career.
indiacardiacsurg

New Vacuum Stabilizer System for CABGG Surgery Procedure Introduced in India - 0 views

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    India's best CABG surgeons perform hundreds of open-heart surgeries every year. The talent and experience of the team afford the foundation for constant excellent patient outcomes, including lower than expected mortality rates in several surgical categories. CABG surgery in India International Helpline Number : +91-9370586696 Email id:enquiry@indiacardiacsurgerysite.com
pharmacybiz

David Webb - England New Chief Pharmaceutical Officer - 0 views

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    David Webb has been appointed as the new chief pharmaceutical officer (CPO) for England. He will take over from Dr Keith Ridge who steps down next month after serving the role for sixteen year. Webb is currently chief pharmacist and clinical director for pharmacy and medicines optimisation at Guy's and Thomas's NHS Foundation Trust, London. Sharing the news of his appointment on Twitter on Friday afternoon (January 7), he said he was "really delighted and honoured" to be named the CPO for NHS England and that he was as the appointed Chief Pharmaceutical officer for "looking forward to working with pharmacy leaders, colleagues & teams across all sectors from February." He also extended his gratitude to the outgoing CPO for his "outstanding contribution" who, in turn, congratulated Webb and said it was "an honour to be handing over to him". In the same message, Dr Ridge thanked "all the great people I've worked with over the last 16 years for your support, friendship, good humour, great ideas & challenge. I wish you all well for the future."
Nathan Goodyear

American College of Cardiology Foundation | Journal of the American College of Cardiolo... - 0 views

  • Although currently no drugs that specifically target mitochondrial biogenesis in HF are available, acceleration of this process through adenosine monophosphate–activated kinase (AMPK), endothelial nitric oxide synthase (eNOS), and other pathways may represent a promising therapeutic approach
  • Mitochondrial biogenesis can be enhanced therapeutically with the use of adenosine monophosphate kinase (AMPK) agonists, stimulants of nitric oxide/cyclic guanosine monophosphate (NO/cGMP) pathway (including phosphodiesteraes type 5 inhibitors), or resveratrol
  • metformin, a commonly used antidiabetic drug that activates AMPK signaling
  • ...10 more annotations...
  • Recent evidence suggests that the eNOS/NO/cGMP pathway is an important activator of mitochondrial biogenesis
  • BH4 (tetrahydrobiopterin) supplementation can prevent eNOS uncoupling and was found to reduce left ventricular hypertrophy
  • folic acid is known to replenish reduced BH4 and has been shown to protect the heart through increased eNOS activity
  • Both folate deficiency and inhibition of BH4 synthesis were associated with reduced mitochondrial number and function
  • Resveratrol, a polyphenol compound responsible for the cardioprotective properties of red wine, was recently identified as a potent stimulator of mitochondrial biogenesis
  • epidemiological studies reveal a reduced risk of cardiovascular disease in premenopausal, but not post-menopausal, women compared with men
  • post-menopausal women
    • Nathan Goodyear
       
      I would hypothesis that a change in the predominance of ER expression is one of ER beta to ER alpha: creating a more pro-inflammatory signal.
  • The majority of ROS in the heart appear to come from uncoupling of mitochondrial electron transport chain at the level of complexes I and III
  • Because the majority of ROS in HF comes from mitochondria, these organelles are the primary target of oxidative damage.
  • cardioprotective therapies such as angiotensin-converting enzyme inhibitors and ATII receptor blockers were shown to possess antioxidant properties, although it is not known whether they target mitochondrial ROS directly or indirectly
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    great review of mitochondrial biogenesis, oxidative stress and heart failure.  
Nathan Goodyear

American College of Cardiology Foundation | Journal of the American College of Cardiolo... - 0 views

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    Small study, but well designed study shows that statins inhibit CoQ10 mediated oxidative phosphorylation through decrease in CoQ10.  This points directly at a decrease in mitochondrial function as a result of statin therapy.
Nathan Goodyear

America's Health Rankings and United Health Foundation - 0 views

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    very nice analysis of the statistics put together by United Health.  Give credit where it is due.  Good job United.
Nathan Goodyear

American College of Cardiology Foundation | Journal of the American College of Cardiolo... - 1 views

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    Endothelial progenitor cells (EPCs) as the future of cardiovascular treatment?
Nathan Goodyear

American College of Cardiology Foundation | Journal of the American College of Cardiolo... - 0 views

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    Study finds that Testosterone therapy improves insulin sensitivity, muscle strength and function in women with advanced CHF.  No levels were noted.  If this is similar to men, I would expect a low Testosterone, which Testosterone replacement would then increase physiologic performance. 
Nathan Goodyear

Marathons damage the hearts of less fit runners for up to three months - - Heart and St... - 0 views

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    Summary of 2010 report on marathons and the heart.  Less fit runners can do significant damage to the heart i.e. fibrosis compared to fit runners.  V02 max is a good way to assess aerobic endurance and differentiate between the two.  Dr Larose showed via MRI that it can take 3 months for the heart to recover.
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