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Nathan Goodyear

Hashimoto's Thyroiditis, Risk of Coronary Heart Disease, and l-Thyroxine Treatment: A N... - 0 views

press.endocrine.org/...jc.2014-2990

Hashimoto's thyroiditis hypothyroidism hypothyroid thyroid heart disease coronary heart disease disease

shared by Nathan Goodyear on 28 Jan 15 - No Cached
  • Nathan Goodyear on 28 Jan 15
     
    Hashimoto's hypothyroidism is associated with a 44% increase in Heart disease in women under the age o 49.  A non-significant change was seen in men.  This study found that T4 therapy reduced this risk.  A better study would have been if T4 was compared to T4 + T3.
Nathan Goodyear

Sex Hormone-Binding Globulin in the Diagnosis of Peripheral Tissue Resistance to Thyroi... - 0 views

jcem.endojournals.org/...740.abstract

hypothyroid thyroid thyroid disease T3 T4 SHBG hormone resistance hormones

shared by Nathan Goodyear on 10 Dec 12 - No Cached
  • Nathan Goodyear on 10 Dec 12
     
    T3, and T4 for that matter, increases SHBG.  This would be a novel method to determine thyroid hormone receptor insensitivity or resistance.
Nathan Goodyear

The thyroid : Oxford Textbook of Endocrinology and Diabetes Oxford Medicine - 0 views

oxfordmedicine.com/...med-9780199235292-section-3

thyroid thyroid disease hormones endocrinology

shared by Nathan Goodyear on 02 Apr 13 - No Cached
  • Nathan Goodyear on 02 Apr 13
     
    Chapter of Thyroid from oxford textbook of endocrinology and diabetes
Nathan Goodyear

Thyroid hormone attenuates cardiac remodeling and ... [Eur J Cardiothorac Surg. 2007] -... - 0 views

www.ncbi.nlm.nih.gov/...17560116

thyroid hormone Cardiovascular disease

shared by Nathan Goodyear on 02 Feb 11 - No Cached
  • CONCLUSIONS: Thyroid hormone administration early after infarction attenuates cardiac remodeling and significantly improves myocardial performance.
  • Nathan Goodyear on 02 Feb 11
     
    Wow, Thyroid replacement after MI, improves heart function and reduces damage
Nathan Goodyear

Thyroid hormone treatment among pregnant women with subclinical hypothyroidism: US nati... - 0 views

www.bmj.com/bmj.i6865

thyroid disease thyroid functional hypothyroidism hypothroidism fertility infertility

shared by Nathan Goodyear on 13 Mar 17 - No Cached
  • Nathan Goodyear on 13 Mar 17
     
    Thyroid therapy in women with subclinical hypothyroidism found to have improved pregnancy rates (lower pregnancy loss).
Nathan Goodyear

Thyroid Hormone and Cardiac Disease: From Basic Concepts to Clinical Application - 0 views

www.ncbi.nlm.nih.gov/...PMC3134399

T3 cardiovascular death disease heart health MI myocardial infarction CHF heart failure thyroid hormone hormones hypothyroid hypothyroidism CVD

shared by Nathan Goodyear on 24 Sep 14 - No Cached
  • Nathan Goodyear on 24 Sep 14
     
    Low T3 post MI is associated with increased CHF, morbidity and mortality.  Article discusses thyroid hormones and cardiac function/remodeling post infarct.  The article also lays the ground work for a new study of T3 in patients post MI to be followed for 6 months.
Nathan Goodyear

The Colorado thyroid disease prevalence study. [Arch Intern Med. 2000] - PubMed result - 0 views

www.ncbi.nlm.nih.gov/...10695693

thyroid disease cholesterol lipids

shared by Nathan Goodyear on 02 Feb 11 - No Cached
  • Nathan Goodyear on 02 Feb 11
     
    Poor thyroid function = poor cholesterol control
Nathan Goodyear

Prevalence of thyroid dysfunction in patients with Ménière's disease. - PubMe... - 0 views

www.ncbi.nlm.nih.gov/...14967756

miner's disease hypothyroid hypothyroidism hormones

shared by Nathan Goodyear on 08 Dec 15 - No Cached
  • Nathan Goodyear on 08 Dec 15
     
    Meniere's disease associated with hypothyroidism patients on thyroid medication in this study.
Nathan Goodyear

The Influence of Age on the Relationship between Subclinical Hypothyroidism and Ischemi... - 0 views

jcem.endojournals.org/...2998.long

subclinical hypothyroidism ischemic heart disease heart heart disease thyroid disease thyroid

shared by Nathan Goodyear on 03 Jul 12 - No Cached
  • Nathan Goodyear on 03 Jul 12
     
    subclinical hypothyroidism is associated with an increase in ischemic heart disease in those <65.
Nathan Goodyear

Biomedical Papers: The prevalence of non organ specific and thyroid autoimmunity in pat... - 0 views

biomed.papers.upol.cz/..._polycystic_ovary_syndrome.php

PTO autoimmune disease autoimmune thyroid PCOS polycystic ovarian syndrome hormones

shared by Nathan Goodyear on 14 Jun 16 - No Cached
  • Nathan Goodyear on 14 Jun 16
     
    high prevalence of thyroid antibodies, TPO, in women with PCOS.  This does not prove cause and effect, merely an association.  Both are inflammation driven.
Nathan Goodyear

The association between TSH within the reference range and serum lipid concentrations i... - 0 views

eje-online.org/...181.long

TSH thyroid lipids cholesterol thyroid disease

shared by Nathan Goodyear on 03 Jul 12 - No Cached
  • Nathan Goodyear on 03 Jul 12
     
    within the normal reference range of TSH, there are wide varying physiologic effects.  Take home: a "normal TSH" doesn't always translate a normal thyroid function.
Nathan Goodyear

Racial and age-related differences in incid... [Am J Clin Pathol. 1994] - PubMed - NCBI - 0 views

www.ncbi.nlm.nih.gov/...8209854

Hashimoto's thyroiditis hypothyroid hypothyroidism thyroid autoimmune disease inflammation hormone hormones

shared by Nathan Goodyear on 28 Aug 13 - No Cached
  • Nathan Goodyear on 28 Aug 13
     
    Hashimoto's thyroiditis is more common in white females.
Nathan Goodyear

Thyroid Function Is Intrinsically Linked to Insulin Sensitivity and Endotheli... - 0 views

jcem.endojournals.org/...3337

thyroid function IR insulin resistance vascular disease

shared by Nathan Goodyear on 01 Feb 11 - No Cached
  • Nathan Goodyear on 01 Feb 11
     
    thyroid, insulin, and vascular function all linked; no linear thinking here
Nathan Goodyear

[Serum thyroid hormone levels correlate with cardi... [J Cardiol. 1993] - PubMed result - 0 views

www.ncbi.nlm.nih.gov/...8176632

hypothyroid hypothyroidism T3 T4 rT3 cardiovascular disease CHF tachycardia

shared by Nathan Goodyear on 01 Feb 11 - No Cached
  • Patients with ventricular tachycardia demonstrated significantly lower serum values of FT3 and FT3/FT4, and significantly higher values of rT3. Serum thyroid hormone levels can provide a quantitative index for evaluating the severity of chronic heart failure and predicting ventricular tachycardia.
  • Nathan Goodyear on 01 Feb 11
     
    Full thyroid evaluation, not TSH or just T4, is predictive in severity of CHF and heart tachycardia
Nathan Goodyear

Low Serum Vitamin D Is Associated with Anti-Thyroid Peroxidase Antibody in Autoimmune T... - 0 views

www.ncbi.nlm.nih.gov/...PMC3936621

vitamin d autoimmune autoimmune disease TPO thyroid antibodies thyroid

shared by Nathan Goodyear on 07 Feb 16 - No Cached
  • Nathan Goodyear on 07 Feb 16
     
    low vitamin D associated with increased TPO antibodies.
Nathan Goodyear

Low-T3 Syndrome - 0 views

circ.ahajournals.org/...708.long

T3 low T3 cardiac heart disease CVD cardiovascular thyroid hormone hormones hypothyroid hypothyroidism

shared by Nathan Goodyear on 03 Jul 12 - No Cached
  • More than 80% of the biologically active hormone triiodothyronine (T3) derives from peripheral conversion of prohormone thyroxine (T4) secreted by the thyroid gland
  • Low thyroid hormone concentrations, in particular low serum T3 concentrations, are a common finding in patients with nonthyroidal illnesses, including cardiac disorders
  • a direct relationship between low circulating levels of T3 and adverse prognosis of cardiac patients
  • ...4 more annotations...
  • The present study clearly shows the existence of a strong association between the reduction of biologically active T3 and mortality in a large population of cardiac hospitalized patients
  • highly significant increase in the incidence of cardiac and cumulative deaths in patients with low T3 compared with patients with normal T3 levels
  • the relevance of the low T3 state as a strong, independent predictor of mortality in cardiac patients
  • low T3 concentrations are a strong independent predictive marker of poor prognosis in cardiac patients
  • Nathan Goodyear on 03 Jul 12
     
    low T3 associated with poor prognosis in cardiac patients.   Poor prognosis = death.  T3 is important in cardiac remodeling, which is inherently important with cardiac disease.
Nathan Goodyear

Incidence of low-triiodothyronine syndrome in patients with septic shock - 0 views

www.ncbi.nlm.nih.gov/...PMC7853677

T4 TSH non-thyroidal illness syndrome septic shock sepsis T3

shared by Nathan Goodyear on 13 Apr 21 - No Cached
  • In the course of different disease states, the levels of T3, T4, and TSH decrease
  • euthyroid sick syndrome
  • low T3 can contribute to associated organ dysfunction
  • ...5 more annotations...
  • proportionally associated with disease severity and survival
  • nonthyroidal illness syndrome
  • Patients with persistent deterioration of hormone levels (T3, T4) during the study period had higher mortality than those who normalized the function of the thyroid axis
  • LT3S in patients with septic shock is part of the pathophysiology of this disease and/or an associated organ (endocrine-metabolic) failure and not just an adaptive phenomenon
  • substitution treatment with synthetic thyroid hormones could modify the hemodynamic symptoms of septic patients, contributing in part to the decrease in their morbidity and mortality
    • Nathan Goodyear
      Nathan Goodyear on 13 Apr 21
       
      Important statement
  • Nathan Goodyear on 13 Apr 21
     
    Septic shock and low T3
Nathan Goodyear

Thyroid Hormone Concentrations, Disease, Physical Function, and Mortality in Elderly Me... - 0 views

jcem.endojournals.org/...6403

hormone thyroid concentrations rT3 reverse T3 hypothyroid hypothyroidism

shared by Nathan Goodyear on 08 Mar 11 - No Cached
  • High serum rT3 may result from a decreased peripheral metabolism of thyroid hormones due to the aging process itself and/or disease and may reflect a catabolic state.
  • Nathan Goodyear on 08 Mar 11
     
    elevated serum rT3 indicates tissue hypothyroidism; very different than rT3 in the pituitary, where high concentrations accumulate
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