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Nathan Goodyear

Unbound MEDLINE | Pilot, Prospective, Randomized, Double-masked, Placebo-controlled Clinical Trial of an Omega-3 Supplement for Dry Eye. Journal article abstract - 0 views

www.unboundmedicine.com/...mega_3_Supplement_for_Dry_Eye_

Omega-3 fish oil dry eyes

shared by Nathan Goodyear on 19 Nov 10 - No Cached
  • the average tear production and tear volume was increased in the omega-3 group
  • Nathan Goodyear on 19 Nov 10
     
    Omega-3 supplementation possible therapy for dry eyes
Nathan Goodyear

Dietary omega-3 fatty acid supplementation increases the rate of muscle protein synthesis in older adults: a randomized controlled trial - 0 views

www.ajcn.org/...402.abstract

omega-3

shared by Nathan Goodyear on 25 Mar 11 - No Cached
  • Omega-3 fatty acids stimulate muscle protein synthesis in older adults
  • Nathan Goodyear on 25 Mar 11
     
    Omega-3 shown to increase muscle growth
Nathan Goodyear

Omega-3 fatty acids in inflammation and autoimmune diseases. - PubMed - NCBI - 0 views

www.ncbi.nlm.nih.gov/...12480795

omega 3 omega-3 fish oil inflammation autoimmune disease

shared by Nathan Goodyear on 07 Feb 16 - No Cached
  • Nathan Goodyear on 07 Feb 16
     
    review article finds omega-3 supplementation reduced inflammation in autoimmune disease.
Nathan Goodyear

Omega-3 polyunsaturated fatty acid supplementation attenuates microglial-induced inflammation by inhibiting the HMGB1/TLR4/NF-κB pathway following experimental traumatic brain injury - 0 views

www.ncbi.nlm.nih.gov/...PMC5525354

omega 3 omega-3 microglia TBI traumatic brain injury brain inflammation

shared by Nathan Goodyear on 01 Aug 17 - No Cached
  • Nathan Goodyear on 01 Aug 17
     
    Omega 3 supplementation found to blunt microglial TBI inflammation. 
Nathan Goodyear

Omega Research - 0 views

www.omega-research.com/researchview.php

omega-3 alzheimer's disease amyloid oxidative stress

shared by Nathan Goodyear on 15 Dec 10 - No Cached
  • Nathan Goodyear on 15 Dec 10
     
    omega-3 limit amyloid and oxidative damage; thus may decrease alzheimer's disease risk
Nathan Goodyear

http://jn.nutrition.org/content/early/2012/01/24/jn.111.155259.full.pdf - 0 views

jn.nutrition.org/...jn.111.155259.full.pdf

n-3 omega 3 omega-3 DHA EPA NF-kappaB inflammation lkappaB-alpha

shared by Nathan Goodyear on 11 Sep 14 - No Cached
  • Nathan Goodyear on 11 Sep 14
     
    Very nice read on effects of n-3 on inflammation.  Omega-3 decreases NF-kappaB via proposed decreased phosphorylation of lkappaBalpha.
Nathan Goodyear

'Metabolic syndrome' in the brain: deficiency in omega-3 fatty acid exacerbates dysfunctions in insulin receptor signalling and cognition - 0 views

jp.physoc.org/...2485.abstract

metabolic syndrome brain insulin fructose resistance omega 3 n-3

shared by Nathan Goodyear on 03 Sep 12 - No Cached
  • n-3 deficient diet and fructose interventions disrupted insulin receptor signalling in hippocampus as evidenced by a decrease in phosphorylation of the insulin receptor and its downstream effector Akt
  • Nathan Goodyear on 03 Sep 12
     
    rats fed high fructose diet and omega-3 diet found to have memory decline.  The purpose of this study was to look at the effects of Metabolic syndrome on the brain.
Nathan Goodyear

PLOS ONE: Effect of Marine-Derived n-3 Polyunsaturated Fatty Acids on C-Reactive Protein, Interleukin 6 and Tumor Necrosis Factor α: A Meta-Analysis - 0 views

www.plosone.org/...10.1371%2Fjournal.pone.0088103

inflammation omega 3 omega-3 n-3 CRP IL-6 TNF-alpha

shared by Nathan Goodyear on 14 Feb 14 - No Cached
  • Nathan Goodyear on 14 Feb 14
     
    meta-analysis finds that omega-3 fatty acids decrease CRP, IL-6, and TNF-alpha.
Nathan Goodyear

Cell - GPR120 Is an Omega-3 Fatty Acid Receptor Mediating Potent Anti-inflammatory and Insulin-Sensitizing Effects - 0 views

www.cell.com/...S0092-8674(10)00888-3

Omega-3 DHA EPA insulin resistance Diabetes

shared by Nathan Goodyear on 15 Feb 11 - No Cached
  • ω-3 FA receptor/sensor and mediates potent insulin sensitizing and antidiabetic effects in vivo
  • Nathan Goodyear on 15 Feb 11
     
    Omega-3 improves insulin sensitivity
Nathan Goodyear

Intake of fish and marine n-3 polyunsaturated fatty acids and risk of breast cancer: meta-analysis of data from 21 independent prospective cohort studies | BMJ - 0 views

www.bmj.com/bmj.f3706

Omega-3 omega 3 fish oil breast cancer breast cancer fish

shared by Nathan Goodyear on 02 Jul 13 - No Cached
  • Nathan Goodyear on 02 Jul 13
     
    Omega 3 associated with decrease Breast cancer risk in women.
Nathan Goodyear

The omega-3 index as a risk factor for coronary heart disease - 0 views

www.ajcn.org/...1997S.full

n-3 omega 3 coronary heart disease sudden cardiac death CVD cardiovascular disease heart cardiology heart disease

shared by Nathan Goodyear on 14 Jul 12 - No Cached
  • Nathan Goodyear on 14 Jul 12
     
    Omega-3 fatty acids can be used to predict risk for coronary heart disease death, especially sudden cardiac death.
Nathan Goodyear

GPR120 is an Omega-3 Fatty Acid Receptor Mediating Potent Anti-Inflammatory and Insulin Sensitizing Effects - 0 views

www.ncbi.nlm.nih.gov/...PMC2956412

Omega-3 n-3 DHA EPA inflammation insulin diabetes DM GPR120 receptor cytokines

shared by Nathan Goodyear on 16 Jul 12 - No Cached
  • Nathan Goodyear on 16 Jul 12
     
    Omega-3, DHA and EPA, exert anti-inflammatory effects through GPR120 receptor.  This improved insulin sensitivity and had diabetes effects in-vivo model.  The effect was through the reduction of macrophage-induced inflammatory cytokines.
Nathan Goodyear

'Metabolic syndrome' in the brain: deficiency in omega-3 fatty acid exacerbates dysfunctions in insulin receptor signalling and cognition - 0 views

jp.physoc.org/2485

HFCS high-fructose corn syrup n-3 omega-3 metabolic syndrome brain insulin MetS

shared by Nathan Goodyear on 16 May 12 - No Cached
  • Nathan Goodyear on 16 May 12
     
    diets with high high-fructose corn syrup and low omega-3 shown to slow cognitive processing in rat model.  This is basically, metabolic syndrome of the brain, as it is the result of hyperinsulinemia.
Nathan Goodyear

Alterations in circulating fatt... [JPEN J Parenter Enteral Nutr. 2011] - PubMed - NCBI - 0 views

www.ncbi.nlm.nih.gov/...21378249

omega 3 omega-3 n-3 fish oil fish oil Lupus fatty acids EPA DHA

shared by Nathan Goodyear on 30 Oct 13 - No Cached
  • Nathan Goodyear on 30 Oct 13
     
    The purpose of this post is not that prednisone should be used to improve the fatty acid profile in those with Lupus.  That is ridiculous.  But, that fatty acid abnormalities are consistently found in Lupus and particularly omega-3 fatty acids should be evaluated.
Nathan Goodyear

A randomised interventional trial of omega-3-p... [Ann Rheum Dis. 2008] - PubMed - NCBI - 0 views

www.ncbi.nlm.nih.gov/...17875549

Lupus omega-3 n-3 fish oil fish oil oxidative stress endothelial function

shared by Nathan Goodyear on 30 Oct 13 - No Cached
  • Nathan Goodyear on 30 Oct 13
     
    Omega-3 supplementation beneficial in patients with Lupus.  This study found a reduction in oxidative stress and endothelial dysfunction
Nathan Goodyear

The combined effects of exercise and foods in preventing neurological and cognitive disorders - 0 views

www.ncbi.nlm.nih.gov/...PMC3258093

diet nutrition exercise BDNF omega-3 omega 3 n-3 brain derived neurotrophic factor curcumin polyphenols neuroplasticity memory sugar saturated fats

shared by Nathan Goodyear on 01 Nov 13 - No Cached
  • The most prevalent types of cognitive impairments include disturbances in attention and learning and memory function
  • An association between BDNF and learning and memory was found when measuring the performance of rats on the Morris water maze task
  • exercise and BDNF have been associated with reducing depression and promoting cognitive enhancement.
  • ...3 more annotations...
  • In addition to reducing oxidative stress and inflammation, DHA serves to improve neuronal function by supporting synaptic membrane fluidity
  • Curcumin has also been shown to protect the hippocampus and to counteract learning impairment
  • insufficient DHA in the brain can compromise neuronal function with subsequent effects on a broad range of neurological and behavioral faculties.
  • Nathan Goodyear on 01 Nov 13
     
    diet and exercise increases BDNF.  Diets rich in omega 3, curcumin, and polyphenols increase BDNF and thus increase neuroplasticity and associated cognition.   In contrast, sugar and saturated fats in crease oxidative stress and worsened spatial learning.  This study is a review.  
Nathan Goodyear

Lipids in Health and Disease | Full text | Omega-3 fatty acids and major depression: A primer for the mental health professional - 0 views

www.lipidworld.com/25

omega-3 fish oil EPA DHA depression Fatty acids lipids

shared by Nathan Goodyear on 23 Nov 10 - No Cached
  • Nathan Goodyear on 23 Nov 10
     
    Omega-3 fatty acids (fish oils) and depression
Nathan Goodyear

Omega-3 fatty acids in juvenile idiopathic ar... [Clin Rheumatol. 2011] - PubMed - NCBI - 0 views

www.ncbi.nlm.nih.gov/...21922187

Omega-3 n-3 Fish oil inflammation idiopathic arthritis NSAIDS IL-1 TNF-alpha fatty acids

shared by Nathan Goodyear on 21 Oct 11 - No Cached
  • Nathan Goodyear on 21 Oct 11
     
    Omega-3 intake reduced inflammation and pain in Juvenile idiopathic arthritis.  Associated inflammatory markers were decreased in study.  Anti-inflammatory drug usage was decreased as well.
Nathan Goodyear

Blood Levels of Long-Chain n-3 Fatty Acids and the Risk of Sudden Death - NEJM - 0 views

www.nejm.org/...NEJMoa012918

omega 3 omega-3 sudden cardiac dealth

shared by Nathan Goodyear on 14 Sep 17 - No Cached
  • Nathan Goodyear on 14 Sep 17
     
    Higher omega 3 fatty acids associated with 81% lower risk of sudden cardiac death.
Nathan Goodyear

Omega-3 fatty acid supplementation and reduction... [J Neurosurg. 2011] - PubMed - NCBI - 0 views

www.ncbi.nlm.nih.gov/...20635852

n-3 omega 3 omega-3 fish oil brain neuroplasticity

shared by Nathan Goodyear on 03 Nov 13 - No Cached
  • Nathan Goodyear on 03 Nov 13
     
    Animal model shows that n-3 intake reduced axonal injury after injury insult.  This implies a use in n-3 intake even after an insult has occured. This implies a role for n-3 in neuroplasticity.
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