Skip to main content

Home/ Dr. Goodyear/ Group items tagged steroids

Rss Feed Group items tagged

Filter: All | Bookmarks | Topics Simple Middle
Nathan Goodyear

Rapid determination of natural steroidal hormones in saliva for the clinical diagnoses - 0 views

www.ncbi.nlm.nih.gov/...PMC3351364

hormone hormones saliva salivary testing estrone estradiol estriol progesterone testosterone natural

shared by Nathan Goodyear on 15 Oct 12 - No Cached
  • Nathan Goodyear on 15 Oct 12
     
    recent study proves the scientific validity of sex hormone evaluation via saliva.  Most labs today use ELIZA.  The new future will be mass spectroscopy.
Nathan Goodyear

Molecular Control of Immune/Inflammatory Responses: Interactions Between Nucl... - 0 views

edrv.endojournals.org/...435.long

progesterone NK macrophage T cell activity inflammation immune system

shared by Nathan Goodyear on 09 Nov 12 - No Cached
  • Nathan Goodyear on 09 Nov 12
     
    Benefits of progesterone, are in part, due to its function on the immune system.  Progesterone shown to decrease T cell activity, macrophage activity and NK cell activity.  Aside, NK cell activity has been found to be increased in those with recurrent first trimester miscarriages and progesterone defects.  So, low progesterone allows for a rise in NK cell activity and inflammation that is detrimental to a developing pregnancy.  If that is the case in pregnancy, what about the rest of the body?
Nathan Goodyear

ScienceDirect.com - Journal of Science and Medicine in Sport - Saliva as a tool for mon... - 0 views

www.sciencedirect.com/...S144024401100048X

saliva salivary hormone hormones

shared by Nathan Goodyear on 14 Nov 12 - No Cached
  • Nathan Goodyear on 14 Nov 12
     
    saliva shown to be valuable and reliable in assessing hormones associated with sport performance, exercise, and/or training.
Nathan Goodyear

An N-terminally truncated third p... [J Steroid Biochem Mol Biol. 1997] - PubMed - NCBI - 0 views

www.ncbi.nlm.nih.gov/...9408082

progesterone receptor progesterone receptors PR-C C progesterone receptor receptors

shared by Nathan Goodyear on 26 Nov 12 - No Cached
  • Nathan Goodyear on 26 Nov 12
     
    progesterone receptor C is a shortened form of PR-A and PR-B.
Nathan Goodyear

Breast Cancer Research | Full text | Progesterone receptors - animal models and cell si... - 0 views

breast-cancer-research.com/...182

PR-A PR-B PR progesterone receptor progesterone receptors progesterone receptor

shared by Nathan Goodyear on 27 Nov 12 - No Cached
  • Nathan Goodyear on 27 Nov 12
     
    good discussion on progesterone receptors, coactivators, corepressors and their impact on breast cancer.  The question is, do these findings have applications to non-disease.
Nathan Goodyear

Inflammation in Polycystic Ovary Syndrome: underpin... [Steroids. 2012] - PubMed - NCBI - 0 views

www.ncbi.nlm.nih.gov/...22178787

PCOS inflammation TNF-alpha androgens women polycystic ovarian syndrome

shared by Nathan Goodyear on 05 Nov 12 - No Cached
  • Nathan Goodyear on 05 Nov 12
     
    In women with PCOS, inflammation DIRECTLY stimulates androgen production from the ovaries.  Inflammation is the driving force behind the high androgen levels in women with PCOS.
Nathan Goodyear

ScienceDirect.com - The Journal of Steroid Biochemistry and Molecular Biology - Differe... - 0 views

www.sciencedirect.com/...S0960076097001192

progesterone receptor progesterone receptors PR-A PR-B progesterone receptor receptors hormone hormones

shared by Nathan Goodyear on 11 May 13 - No Cached
  • Nathan Goodyear on 11 May 13
     
    progesterone receptor status varies through a woman's menstrual cycle. PR-A dominates throughout, but the PR-A to PR-B ratio declines up to ovulation.
Nathan Goodyear

Dehydroepiandrosterone (DHEA)--a precursor steroid... [J Sex Med. 2011] - PubMed - NCBI - 0 views

www.ncbi.nlm.nih.gov/...22032408

DHEA inflammation hormone hormones

shared by Nathan Goodyear on 02 Jun 13 - No Cached
  • Nathan Goodyear on 02 Jun 13
     
    DHEA reduces inflammation, improves insulin function, and provides improved cognitive function.
Nathan Goodyear

Sex Steroid Hormone Levels and Body Composition in Men - 0 views

jcem.endojournals.org/...2442.abstract

hormone body composition hormones body composition Testosterone Estradiol E2 T SHBG

shared by Nathan Goodyear on 10 Jun 13 - No Cached
  • Nathan Goodyear on 10 Jun 13
     
    The results of this study: body composition i.e. fat, effects hormone levels, rather then hormone effecting body composition.  
Nathan Goodyear

Androgen insufficiency in women: diagnostic and therapeutic implications - 0 views

humupd.oxfordjournals.org/...421.full

SHBG androgen testosterone androgens DHT women insufficiency deficiency

shared by Nathan Goodyear on 12 Jun 13 - No Cached
  • SHBG has a differing binding affinity for sex steroids in the following order; DHT > testosterone > androstenedione > estradiol > estrone
  • SHBG also weakly binds DHEA, but not DHEAS
  • Nathan Goodyear on 12 Jun 13
     
    Good discuss of androgen deficiency in women.  Also, good discussion of SHBG.  
Nathan Goodyear

Short-term changes in serum sex steroid levels and cardiac function in healthy young men - 0 views

www.endocrine-abstracts.org/...ea0032p182.htm

men male hormone hormones aromatase CVD cardiovascular disease estrogen testosterone low T low testosterone

shared by Nathan Goodyear on 07 Jun 13 - No Cached
  • Nathan Goodyear on 07 Jun 13
     
    High aromatase activity in men, as a result of abdominal fat associated with increased estrogen production and lowered Testosterone.  The result is increased CVD.  It's a man boob nation.
Nathan Goodyear

Combining xenoestrogens at levels below individual no-observed-effect concentrations dr... - 0 views

www.ncbi.nlm.nih.gov/...ehp0110-000917.pdf

xenoestrogens xenoestrogen environmental toxins estrogen hormones hormone

shared by Nathan Goodyear on 15 Dec 12 - No Cached
  • Nathan Goodyear on 15 Dec 12
     
    low levels of environmental toxins add to the effective hormone levels in the body. These are in very low levels of exposure.
Nathan Goodyear

ScienceDirect.com - The Journal of Steroid Biochemistry and Molecular Biology - Estroge... - 0 views

www.sciencedirect.com/...S0960076011001518

xenoestrogen xenoestrogens prostate male hormone estrogen receptor estrogen receptor alpha ER alpha estrogen receptor receptors environmental chemicals drugs

shared by Nathan Goodyear on 07 Jan 13 - No Cached
  • Nathan Goodyear on 07 Jan 13
     
    low dose xenoestrogen exposure increases prostate growth and future disease through fetal exposure and increased ER alpha expression.
Nathan Goodyear

Endocrinology of the Aging Male - 0 views

www.ncbi.nlm.nih.gov/...PMC3073592

aging male hormone hormones

shared by Nathan Goodyear on 30 Apr 13 - No Cached
  • All steps beyond the formation of pregnenolone take place in the smooth endoplasmic reticulum
  • Cytochrome P450 enzyme, CYP11A is located on the inner mitochondrial membrane and catalyses the rate limiting step of pregnenolone synthesis
  • Estrogen and related steroids, thyroid hormone and insulin increase SHBG levels.
  • ...21 more annotations...
  • SHBG decreases in response to androgens, and in the presence of hypothyroidism, and insulin resistance.
  • Plasma SHBG levels tend to increase with increasing age
  • The apparent metabolic clearance rate of testosterone is decreased in elderly as compared to younger men
  • Testosterone circulates predominantly bound to the plasma proteins SHBG and albumin, with high and low affinity respectively
  • Testosterone is secreted in a pulsatile fashion
  • Current clinical guidelines suggest at least two measurements
  • In adult men, there is a well-documented diurnal variation (particularly in younger subjects) in testosterone levels, which are highest in the early morning and progressively decline throughout the day to a nadir in the evening
  • In older men, the diurnal variation is blunted
  • it is standard practice for samples to be obtained between 0800 and 1100 h.
  • Testosterone and DHEA decline, whereas LH, FSH, and SHBG rise
  • DHT remains constant despite the decline of its precursor testosterone
  • Longitudinal studies show an average annual decline of 1–2% total testosterone levels, with decline in free testosterone more rapid because of increases in SHBG with aging
  • Massachusetts Male Aging Study (MMAS) data show DHEA, DHEAS, and Ae declining at 2–3% per year
  • DHT showed no cross-sectional age trend
  • Androstanediol glucuronide (AAG) declined cross-sectionally with age in the MMAS sample, at 0.6% per year
  • The EMAS data show that, consistent with the longitudinal findings of MMAS (Figure 1), the core hormonal pattern with increasing age is suggestive of incipient primary testicular dysfunction with maintained total testosterone and progressively blunted free testosterone associated with higher LH
    • Nathan Goodyear
      Nathan Goodyear on 01 May 13
       
      This author proves the point in the review of these two studies, that TT may remain constant in aging men, however, FT drops.
  • obesity impairs hypothalamic/pituitary function
  • Androgen deprivation in men with prostate cancer has been associated with increased insulin resistance, worse glycemic control, and a significant increase in risk of incident diabetes
  • Low serum testosterone is associated with the development of metabolic syndrome 116, 117 and type 2 diabetes. 118 SHBG has been inversely correlated with type 2 diabetes
  • Improvement in insulin sensitivity with testosterone treatment has been reported in healthy 121 and diabetic 122 adult men
  • In studies conducted in men with central adiposity, testosterone has been shown to inhibit lipoprotein lipase activity in abdominal adipose tissue leading to decreased triglyceride uptake in central fat depots. 123
  • Nathan Goodyear on 30 Apr 13
     
    great review of hormone changes associated with aging in men.
Nathan Goodyear

Sex steroid hormone exposures and risk for menin... [J Neurosurg. 2003] - PubMed - NCBI - 0 views

www.ncbi.nlm.nih.gov/...14609164

hormone hormones women female meningioma

shared by Nathan Goodyear on 05 Feb 13 - No Cached
  • Nathan Goodyear on 05 Feb 13
     
    Both endogenous and exogenous hormone exposure in women is associated with increased risk for meningioma.
Nathan Goodyear

Steroid Analysis in Saliva: An overview - 0 views

www.ncbi.nlm.nih.gov/...PMC1579286

saliva salivary hormone testing hormones

shared by Nathan Goodyear on 26 Jun 13 - No Cached
  • Nathan Goodyear on 26 Jun 13
     
    No test is perfect. This study analyzes problems with saliva hormone testing.  The authors of this study found saliva testing optimal for cortisol and less so for sex hormones.  Other studies have contradicted this conclusion.
Nathan Goodyear

Adrenal and gonadal steroid hormone deficiency in the pathogenesis of rheumatoid arthri... - 0 views

www.ncbi.nlm.nih.gov/...8833045

rheumatoid arthritis RA hormones autoimmune disease

shared by Nathan Goodyear on 09 May 16 - No Cached
  • Nathan Goodyear on 09 May 16
     
    Only abstract available here.  Low adrenal hormone output and low sex hormone production associated with increase RA.  Causation not proved here.
Nathan Goodyear

Anabolic androgenic steroids, an easily forgotten cause of polycythaemia and cerebral i... - 0 views

www.ncbi.nlm.nih.gov/...27062206

Testosterone men hormones polycythemia stroke CVA

shared by Nathan Goodyear on 12 Apr 16 - No Cached
  • Nathan Goodyear on 12 Apr 16
     
    Only abstract available here.  Supra-physiologic Testosterone therapy needs to be included in potential causes of polycythemia and stroke in men.  Remember the 25-50-21 rule in that 25% of men on Testosterone therapy are never checked prior to initiation of Testosterone and 50% are not followed after initiation of Testosterone therapy.
Nathan Goodyear

Peptide and steroid hormone levels in pre- and postmenopausal breast carcinoma. - PubMe... - 0 views

www.ncbi.nlm.nih.gov/...3104809

hormones breast cancer cancer estrogen progesterone testosterone prolactin female hormones women

shared by Nathan Goodyear on 15 Sep 16 - No Cached
  • Nathan Goodyear on 15 Sep 16
     
    elevated Testosterone found to play role in post menopause breast cancer.  No correlation with elevated Testosterone was found in pre menopause--in fact, low estrogen/low Testosterone and elevated prolactin was found in pre menopausal breast cancer patients.
Nathan Goodyear

Variations in urine excretion of steroid hormones after an acute session and after a 4-... - 0 views

link.springer.com/...10.1007%2Fs00421-006-0319-1

androgens Testosterone resistance training exercise male hormones

shared by Nathan Goodyear on 14 Feb 17 - No Cached
  • Nathan Goodyear on 14 Feb 17
     
    4 week resistance training program found to increase androgens in urine; this suggests increased androgen production as a result of the resistance program
« First ‹ Previous 41 - 60 of 170 Next › Last »
Showing 20▼ items per page