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Nathan Goodyear

PLOS ONE: Negative Association between Testosterone Concentration and Inflammatory Mark... - 0 views

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    Testosterone is inversely associated with inflammatory cytokines and thus low T can be used as a marker of poor health in men.  This study found a specific association with TNF-alpha and MIP1-alpha.  
Nathan Goodyear

Metabolic Syndrome ePoster - 0 views

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    Great pictorials of the biochemistry of metabolic syndrome.
Nathan Goodyear

Molecular Control of Immune/Inflammatory Responses: Interactions Between Nucl... - 0 views

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    Benefits of progesterone, are in part, due to its function on the immune system.  Progesterone shown to decrease T cell activity, macrophage activity and NK cell activity.  Aside, NK cell activity has been found to be increased in those with recurrent first trimester miscarriages and progesterone defects.  So, low progesterone allows for a rise in NK cell activity and inflammation that is detrimental to a developing pregnancy.  If that is the case in pregnancy, what about the rest of the body?
Nathan Goodyear

Regulatory Mechanisms for Adipose Tissue M1 and M2 Macrophages in Diet-Induced Obese Mice - 0 views

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    M1 macrophages (and a high M1/M2 ratio) promote inflammation and insulin resistance in obese individuals; This is in contrast to M2 macrophages.  Obese individuals will see a shift in M2 to M1.  The exact mechanism is yet unknown.  But M2 macrophages have been shown to resolve insulin resistance in this obese mice model
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