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Nathan Goodyear

Altered D-Chiro-Inositol Urinary Clearance in Women With Polycystic Ovary Syndrome - 0 views

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    low D-chiro-inositol contributes to insulin resistance and thus role in PCOS
Nathan Goodyear

Effect of a low glycemic index compared with a conventional healthy diet on polycystic ... - 0 views

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    low glycemic diet for ladies with polycystic ovaries
Nathan Goodyear

Hyperprolactinemia in polycystIc ovary syndrome - 0 views

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    Study finds Prolactin not associated with PCOS.
Nathan Goodyear

Androgen therapy and atherosclerotic cardiovascular disease - 0 views

  • In women, it is much clearer that androgen excess is linked to the burden of CVD risk factors
  • insulin resistance is a consequence of androgen effects
  • Women with PCOS have a sustained exposure to high physiologic androgen levels. This condition is associated with endothelial dysfunction, obesity and metabolic abnormalities such as insulin resistance and dyslipidaemia
  • ...4 more annotations...
  • Further evidence of a link between high androgen levels and CVD or CVD risk factors is observed in women with polycystic ovary syndrome (PCOS)
  • For T treatment in aging women, the current data would suggest androgen excess has adverse effects on CVD risk factors, especially in women with diabetes
  • androgen use and abuse is increasing in our society, either for therapeutic or recreational reasons
  • For men, exogenous T treatment appears largely beneficial
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    I love these review articles that highlight the metabolic differences of hormones in women versus men.  The medical community as a whole doesn't seem to get this at all.  The marketing-based medical community doesn't either.
Nathan Goodyear

Journal of Endocrinological Investigation - 0 views

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    vitamin D therapy shown to reduce total cholesterol and triglycerides in those with low vitamin D levels.
Nathan Goodyear

Saliva as a matrix for measuring free androgens: comparison with serum androgens in pol... - 0 views

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    early study looking at saliva testing in infertility treatment.  This goes back almost 33 years.  But of course, it took medicine 176 years to recommend that Vitamin C help prevent scurvy on long sea journeys.
Nathan Goodyear

Effects of metformin with or without supplemen... [Diabetes Care. 2010] - PubMed - NCBI - 0 views

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    metformin shown to result in increased homocysteine through depletion of folate. Metformin is also known to deplete vitamin B12 and CoQ10.  
Nathan Goodyear

Circulating Ghrelin Levels Are Decreased in Human Obesity - 0 views

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    low ghrelin levels found in obese individuals (Pima Indians).  Low ghrelin was associated with an inverse increase in fat, insulin, and leptin. It has also been shown to be associated with an inverse increase in Testosterone.
Nathan Goodyear

The effect of oral micronized progesterone on ... [Fertil Steril. 2010] - PubMed - NCBI - 0 views

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    The effect of oral micronized progesterone on hormonal and metabolic parameters in anovulatory patients with polycystic ovary syndrome.
Nathan Goodyear

High-dose vitamin D supplementation and measur... [Fertil Steril. 2014] - PubMed - NCBI - 0 views

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    No significant statistical significance was found with vitamin D therapy and insulin sensitivity.  However, improved outcomes were found in 2 hour insulin and 2 hour glucose levels after a 75 gram OGTT.
Nathan Goodyear

Ovulatory and metabolic effects of D-chiro-inosito... [N Engl J Med. 1999] - PubMed result - 0 views

  • Chiro-inositol increases the action of insulin in patients with the polycystic ovary syndrome, thereby improving ovulatory function and decreasing serum androgen concentrations, blood pressure, and plasma triglyceride concentrations.
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    Chiro-inositol increases the action of insulin in patients with the polycystic ovary syndrome
Nathan Goodyear

D-chiro-inositol glycans in insulin signaling and ... [Mol Med. 2010 Nov-Dec] - PubMed ... - 0 views

  • The metabolism of DCI is associated with insulin sensitivity and resistance, supporting the concept that second messengers have a role in responses to and resistance to insulin.
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    D-chiro-inositol is a secondary messenger in the insulin signaling pathway
Nathan Goodyear

Cell - Insulin Signaling: Inositol Phosphates Get into the Akt - 0 views

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    Inositol phsophoglycans part of insulin signaling pathways
Nathan Goodyear

Inositolphosphoglycans (IPGs) as mediators of insu... [J Basic Clin Physiol Pharmacol. ... - 0 views

  • There is substantial evidence to suggest that some IPGs may also be responsible in part for mediating insulin's stimulation of glucose disposal
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    Inositolphosphoglycans function as intermediate in insulin/glucose regulation
Nathan Goodyear

Insulin Stimulates Testosterone Biosynthesis by Human Thecal Cells from Women with Poly... - 0 views

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    insulin stimulates testosterone production with Chiro-inositol as a mediator in signaling
Nathan Goodyear

Inflammation in Polycystic Ovary Syndrome: Underpinning of insulin resistance and ovari... - 0 views

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    Study points to inflammation causing hyperandrogenism via ovarian theca stimulation.
vishal Parasrampuria

PET a Very Crucial Raw Material For Packaging - 0 views

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    PET has been in use from quite a long time, but recent years showed a great surge in the demand worldwide. Easy availability of the PET material has great emphasis on packaging due to high-quality production with reduced costs. According to a forecast from Smithers Pira, there will be a sustained annual growth of 4.6 percent year-on-year basis in next five years. Other than established economies, transitional and emerging ones become prominent players in the marketplace.
vishal Parasrampuria

How to Perform Testing of Glass and PET bottles? - 0 views

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    Some of the testing procedures are as same as Pet bottle testing. However, glass bottles don't undergo bursting tests etc. If the quality manager wants to do the same, there are specially designed machines with closed cavities, to avoid any mishap when bottle bursts.
Nathan Goodyear

Thieme E-Journals - Hormone and Metabolic Research / Abstract - 0 views

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    Short study found that Selenium improved pregnancy rate compared to placebo, reduced DHEA, hirsutism, CRP and MDA
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