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Nathan Goodyear

Inositolphosphoglycans (IPGs) as mediators of insu... [J Basic Clin Physiol Pharmacol. ... - 0 views

  • There is substantial evidence to suggest that some IPGs may also be responsible in part for mediating insulin's stimulation of glucose disposal
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    Inositolphosphoglycans function as intermediate in insulin/glucose regulation
Nathan Goodyear

Role of inositolphosphoglycan mediators of insulin... [J Pediatr Endocrinol Metab. 2000... - 0 views

  • some actions of insulin are mediated by putative inositolphosphoglycan (IPG) mediators
  • known as second messengers
  • echanism by which insulin can stimulate ovarian androgen production even in women with PCOS
  • ...3 more annotations...
  • a deficiency in a specific D-chiro-inositol-containing IPG may contribute to insulin resistance in women with PCOS
  • IPG signaling system transduces insulin's stimulation of human thecal androgen biosynthesis
  • administration of D-chiro-inositol has been demonstrated to improve glucose tolerance, decrease serum androgens and improve ovulation in PCOS
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    D-chiro-inositol deficiency and its role in PCOS, insulin resistance, and hyperandrogenism
Nathan Goodyear

Insulin mediators are the signal transduction syst... [Endocrinology. 1991] - PubMed re... - 0 views

  • inositolglycan mediators are the signal transduction mechanism responsible for insulin's regulation of human placental steroid hormone biosynthesis.
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    inositolphosphoglycans act as signal transducers in steroid pathway synthesis
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