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Nathan Goodyear

D-chiro-inositol metabolism in diabetes mellitus - 0 views

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    d-chiro-inositol levels shown to be low in diabetics.  Thus, d-chiro-inositol would prove to be helpful in diabetes management.  D-chiro-inositol is a secondary messenger in insulin signaling
Nathan Goodyear

Comparison between effects of myo-inosito... [Gynecol Endocrinol. 2013] - PubMed - NCBI - 0 views

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    Myo-inositol and D-chiro-inositol improve metabolic function in women with PCOS.  Myo-inositol appears to have better effects on metabolic profile and D-chiro-inositol on reduced androgen effects.
Nathan Goodyear

Role of inositolphosphoglycan mediators of insulin... [J Pediatr Endocrinol Metab. 2000... - 0 views

  • some actions of insulin are mediated by putative inositolphosphoglycan (IPG) mediators
  • known as second messengers
  • echanism by which insulin can stimulate ovarian androgen production even in women with PCOS
  • ...3 more annotations...
  • IPG signaling system transduces insulin's stimulation of human thecal androgen biosynthesis
  • a deficiency in a specific D-chiro-inositol-containing IPG may contribute to insulin resistance in women with PCOS
  • administration of D-chiro-inositol has been demonstrated to improve glucose tolerance, decrease serum androgens and improve ovulation in PCOS
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    D-chiro-inositol deficiency and its role in PCOS, insulin resistance, and hyperandrogenism
Nathan Goodyear

Effects of d-chiro-inositol in lean women with the... [Endocr Pract. 2002 Nov-Dec] - Pu... - 0 views

  • women with the polycystic ovary syndrome, D-chiro-inositol reduces circulating insulin, decreases serum androgens, and ameliorates some of the metabolic abnormalities (increased blood pressure and hypertriglyceridemia) of syndrome X.
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    D-chiro-inositol reduced insulin levels and associated male hormone production in lean women with PCOS
Nathan Goodyear

The Combined therapy myo-inositol ... [Eur Rev Med Pharmacol Sci. 2013] - PubMed - NCBI - 0 views

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    Combination therapy of d-chiro-inositol and myo-inositol improve metabolic markers of PCOS.
Nathan Goodyear

Ovulatory and metabolic effects of D-chiro-inosito... [N Engl J Med. 1999] - PubMed result - 0 views

  • Chiro-inositol increases the action of insulin in patients with the polycystic ovary syndrome, thereby improving ovulatory function and decreasing serum androgen concentrations, blood pressure, and plasma triglyceride concentrations.
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    Chiro-inositol increases the action of insulin in patients with the polycystic ovary syndrome
Nathan Goodyear

D-chiro-inositol glycans in insulin signaling and ... [Mol Med. 2010 Nov-Dec] - PubMed ... - 0 views

  • The metabolism of DCI is associated with insulin sensitivity and resistance, supporting the concept that second messengers have a role in responses to and resistance to insulin.
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    D-chiro-inositol is a secondary messenger in the insulin signaling pathway
Nathan Goodyear

Altered D-Chiro-Inositol Urinary Clearance in Women With Polycystic Ovary Syndrome - 0 views

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    low D-chiro-inositol contributes to insulin resistance and thus role in PCOS
Nathan Goodyear

Insulin-stimulated release of D-chiro-inositol-co... [Metabolism. 2008] - PubMed - NCBI - 0 views

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    D-chiro-inositol release correlated with improved insulin sensitivity.
Nathan Goodyear

D-Chiro-Inositol - Its Functional Role in Insulin Action and its Deficit in Insulin Res... - 0 views

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    d-chiro-inositol improves insulin sensitivity and thus reduces insulin resistance
Nathan Goodyear

KoMCI.org - 0 views

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    D-chiro-inositol shown to be reduced in urinary testing in type 1 and 2 diabetics
Nathan Goodyear

JSTOR: Proceedings of the National Academy of Sciences of the United States of America,... - 0 views

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    D-chiro-inositol in diabetes
Nathan Goodyear

Cell - Insulin Signaling: Inositol Phosphates Get into the Akt - 0 views

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    Inositol phsophoglycans part of insulin signaling pathways
Nathan Goodyear

Uncoupling between insulin and rele... [Metab Syndr Relat Disord. 2010] - PubMed - NCBI - 0 views

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    Obese women with PCOS found to have uncoupled insulin and d-chiro-inositol secretion thus worsening insulin resistance
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