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Nathan Goodyear

Metabolic Effects of Liothyronine Therapy in Hypothyroidism: A Randomized, Double-Blind... - 0 views

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    T3 shown increase weight loss, lower LDL, decrease apolipoprotein B, decrease T cholesterol versus T4.  This flies in the face of conventional medical dogma, that T 4 (synthroid, levothyroxine) is the only route of thyroid replacement.  In fact, this suppports the use of armour thyroid, a T4/T3 combination.
Nathan Goodyear

M2 macrophages exhibit higher sensitivity to oxLDL-induced lipotoxicity than other mono... - 0 views

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    macrophages (M1) in obese individuals are more pro-inflammatory than those in lean (M2) individuals. The exact mechanism to explain the switch from M2 to M1 has yet to be determined, but this study proposes that lipotoxic oxidized LDL is a possible target
Nathan Goodyear

Effects of supplementation with fish oil-derived n−3 fatty acids and γ-linole... - 0 views

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    mixture of omega-3 and GLA shown to statistically lower LDL.  The mixture that was statistically significant was 4:2.
Nathan Goodyear

Testosterone Replacement in Hypogonadal Men With Type 2 Diabetes and/or Metabolic Syndr... - 0 views

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    testosterone therapy in men with low Testosterone shown to improve insulin resistance, lower cholesterol and LDL, lower LpA, and improve ED.
Nathan Goodyear

Purified eicosapentaenoic and docosahexaenoic acids have differential effects on serum ... - 0 views

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    EPA and DHA have differing effects in men with Hyperlipidemia.  DHA increased LDL particle size, increased fasting insulin, but did not increase fasting glucose.
Nathan Goodyear

Obesity - Amelioration of Lipid Abnormalities by [alpha]-Lipoic acid Through Antioxidat... - 0 views

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    alpha lipoic acid found to improve insulin sensitivity and reduce oxidative stress and inflammatory markers.  In this study, IV ALA was given daily for 2 weeks, and the result was reduced oxidized LDL and all other lipids, improved insulin sensitivity, reduced TNF-alpha, IL-6, and 8-iso-prostaglandin, and increased adiponectin.
Nathan Goodyear

Plasma lipoproteins are important components of the immune system - Han - 2010 - Microb... - 0 views

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    Is all cholesterol bad?  Of course not.  We have got to get away from the linear thinking that plagues medicine.  This article proposes and supports  a protective claim of lipoproteins: VLDL, LDL, Lp(a), and HDL.  Even shown to protect against bacterial, viral, LPS, and parasitic infectious damage.
Nathan Goodyear

Low Doses of Lipopolysaccharide and Minimally Oxidized Low-Density Lipoprotei... - 0 views

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    LPS and minimal oxidized LDL have synergistic effects on inflammatory signaling.  Together the two promote inflammatory signaling from macrophages at much lower levels than either one alone.  They do this through macrophage NF-KappaB and AP-1 pathways.  And this resultant inflammation promotes atherosclerosis.  Where does all this start?  our diet and our gut.
Nathan Goodyear

The relationship between endogenous testost... [Eur J Endocrinol. 2014] - PubMed - NCBI - 0 views

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    Study finds Testosterone inversely associated with TC, TG, and LDL, but positively associated with HDL.  The evidence on Testosterone and lipids are mixed.  This study shows positive effects all the way around.
Nathan Goodyear

Association between plasma total tes... [J Clin Endocrinol Metab. 1997] - PubMed - NCBI - 0 views

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    low Total Testosterone associated with increased BMI, systolic blood pressure, glucose, triglycerides, total cholesterol, LDL apolipoprotien B and A1. Low Testosterone is associated with increased cardiovascular disease.  Men at risk for cardiovascular disease must be evaluated for hormones.
Nathan Goodyear

ARS | Publication request: Sex hormone modulation of proinflammatory cytokine and CRP e... - 0 views

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    Study finds that Testosterone provided a small anti-inflammatory effect in post-menopausal women and men, whereas Estrogen increased macrophage cytokine production in post-menopausal women with elevated LDL.  Now, this study did not differentiate PCOS versus non-PCOS, nor did it look at the effects of adiposity in these hormonal effects in women.  Both of which, will effect the outcome.
Nathan Goodyear

Nutrition Journal | Full text | A daily glass of red wine associated with lifestyle cha... - 0 views

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    tools for health are all around us.  red wine reduced the LDL/HDL ratio by 13% in patients with carotid arteriosclerosis.  This occurred  independently from dietary changes and exercise.
Nathan Goodyear

Association between low-dose folic acid supple... [Med Sci Monit. 2013] - PubMed - NCBI - 0 views

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    400 mcg Folic acid shown to reduce total cholesteroel and LDL-C in women and men.  Additionally, apoAI is increased.
Nathan Goodyear

Subclinical hypothyroidism ... [Eur J Obstet Gynecol Reprod Biol. 2014] - PubMed - NCBI - 0 views

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    Women with PCOS need a closer follow of their thyroid function.  TSH positively correlated with increasing LDL.
Nathan Goodyear

Effects of calcium-vitamin D co-supplementation... [Diabetologia. 2014] - PubMed - NCBI - 0 views

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    vitamin D plus calcium in those with Diabetes and low vitamin D four to improve insulin resistance, HDL, LDL, beta cell function, and HgbA1c.  This was a short course study of 8 weeks.  Only abstract available.
Nathan Goodyear

Beneficial effects of melatonin on obesity and lipid profile in young Zucker diabetic f... - 0 views

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    melatonin appears to help in weight loss and improve LDL and HDL cholesterol levels
Nathan Goodyear

Association of serum testosterone with lipid abnormalities in patients with angiographi... - 0 views

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    This study looked at Total serum Testosterone and lipid profiles in men with CAD.  What they found is that serum Total Testosterone is positively associated with HDL and negatively associated with LDL.
Nathan Goodyear

Testosterone Supplementation Improves Carbohydrate and Lipid Metabolism in Some Older M... - 0 views

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    In some men, Testosterone therapy (10 mg transdermal) is associated with adipose tissue.  In those with a decrease in adipose tissue, a decrease in LDL, decrease in Triglycerides, increase in insulin sensitivity, and lower HDL were found.
Nathan Goodyear

Testosterone Replacement in Hypogonadal Men With Type 2 Diabetes and/or Metabolic Syndr... - 0 views

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    Testosterone therapy in men with low Testosterone was found to improve insulin sensitivity, total cholesterol levels, LDL, Lpa, and sexual performance in men with low T, type II diabetes and/or metabolic syndrome.  There is suggestion that muscle composition was improved as well.
Nathan Goodyear

The Evaluation of Serum Levels of Testosterone in Type 2 Diabetic Men and Its Relation ... - 0 views

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    Small study of 2 men with type II diabetes finds fasting glucose levels negatively correlate with total and free Testosterone levels, HgbA1c negatively correlated with SHBG only, total cholesterol and LDL negatively correlated with SHBG and total testosterone.  The prevalence of type II diabetes was higher with low free Testosterone than total Testosterone, but both were statistically significant.
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