3 year study finds improvement in classic menopausal symptoms for women in perimenopause and menopause with improvement in other parameters: fasting glucose, cholesterol, MMP-9, CRP, fibrinogen and other clotting factors. This study used bioidentical Bi-est, progesterone, and in some DHEA and Testosterone.
Estrogen therapy in women recently postmenopausal, found to improve symptoms of depression and anxiety. The mean age of women in this study was 52.7. Average age of menopause is 51, so apprx 1 year postmenopausal in this study. Both premarin and bioidentical estradiol was used in different arms of the study. Bioidentical progesterone was used in all 3 arms.
Study finds that low estrogen, assuming estradiol, higher FSH, low epinephrine, higher norepinephrine are associated with severe hot flashes. Of interesting note, Cortisol and Testosterone were not associated with symptom severity.
women with complaints of flushing or night sweats have an unfavorable cardiovascular risk profile compared
with women without vasomotor complaints and with increased cholesterol levels, systolic and diastolic blood pressures, and
BMI.
Study finds non-hormonal therapy to manage hot flashes in postmenopausal women--drug them. The authors of this study, looked to gabapentin, also known as neurontin to treat hot flashes. Instead of looking at the causes: hormone imbalance, stress... these authors looked to a sedating drug. The dosing of neurontin was 900 mg. Most can't stand at this dose. This study points to the lunacy in the research today. Very soon, there will be the walking dead among us. They will be the walking doped instead of dead.
Approximately 80% of women reported overall satisfaction with the micronized progesterone-containing regimen. A micronized progesterone-containing HRT regimen offers the potential for improved QOL as measured by improvement of menopause-associated symptoms.
Hot flashes reduced with weight loss in those not taking HRT. Reduced fat equals reduced inflammation equals reduced hot flashes/night sweats. The more inflamed an individual, the more prevalent/significant the hot flashes.
Interesting: study finds no association between tryptophan and serotonin levels and depression. The study found no difference between 44 "depressed" perimenopausal women and 19 "without depression". Serotonin therapy of depression?? However, poor sleep and hot flashes did.