at both progestogen and glucocorticoid receptors may mediate the effects of high-dose MPA therapy in breast cancer. The possible stimulation of the growth of some cell types by MPA requires further investigation.
Recurrent early pregnancy losses can be prevented not with provera, not with progestin, but with progesterone. The use of progesterone by the functional medicine movement has long been advocated and supported in the science; now the allopathic medicine will try to claim it as its own.
study of 80,377 postmenopausal women found no increase/decrease in breast cancer in women on estradiol and progesterone (RR 1.0). However, estradiol and provera (synthetic progestin) found a 69% increased breast cancer risk (RR 1.69).
This study found that increasing Testosterone, as determined by serum, is associated with increased CVD, insulin resistance, and metabolic syndrome in postmenopausal women. I believe that this massive Testosterone doping campaign that we are seeing in men and women is following the same patter seen with premarin and provera.
Prospective study finds that elevated total and free Estradiol levels in the follicular phase and elevated total and free Testosterone levels in both the follicular and luteal phase are associated with increased breast cancer in women. The risk is for pre menopause in this study. This and several other studies point to serious questions about the massive dosing of Testosterone via pellets, injections, and topicals for libido. We appear to be following the same patter as seen with premarin, provera, now Testosterone in men and this may be the next ball to drop. Is the Testosterone therapy merely producing an environment that feeds breast cancer?
Yale study finds estrogen therapy in improves health in women ages 50-59. The problems with hormone therapy is synthetics and overdosing. The problem with the WHI was they used medroxy progesterone acetate--a synthetic progestin. That is not progesterone. This study estimated that 91,000 + died due to the uneducated view that estrogen HRT is dangerous. What is dangerous is leaving the HRT and BHRT recommendations to those with conflicts of interest and a lack of knowledge of the science.
Approximately 80% of women reported overall satisfaction with the micronized progesterone-containing regimen. A micronized progesterone-containing HRT regimen offers the potential for improved QOL as measured by improvement of menopause-associated symptoms.